Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance

Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status, and ion transporter gene expression

(2011) S. Ghosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The WxxxE effector EspT triggers expression of immune mediators in an Erk/JNK and NF-κB-dependent manner

(2011) Benoit Raymond et al.   CELLULAR MICROBIOLOGY

The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

(2011) Yun-Gi Kim et al.   IMMUNITY

Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and p38 Mitogen-Activated Protein Kinase Activation

(2011) Ho Pan Sham et al.   INFECTION AND IMMUNITY

The Type III System-Secreted Effector EspZ Localizes to Host Mitochondria and Interacts with the Translocase of Inner Mitochondrial Membrane 17b

(2011) Stephanie R. Shames et al.   INFECTION AND IMMUNITY

Early MyD88-Dependent Induction of Interleukin-17A Expression during Salmonella Colitis

(2011) A. Marijke Keestra et al.   INFECTION AND IMMUNITY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

(2011) Kaoru Geddes et al.   NATURE MEDICINE

Altering Host Resistance to Infections through Microbial Transplantation

(2011) Benjamin P. Willing et al.   PLoS One

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Interleukin-11 Reduces TLR4-Induced Colitis in TLR2-Deficient Mice and Restores Intestinal STAT3 Signaling

(2010) Deanna L. Gibson et al.   GASTROENTEROLOGY

Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model

(2010) K. Geddes et al.   INFECTION AND IMMUNITY

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

(2010) Simon A. Hirota et al.   INFLAMMATORY BOWEL DISEASES

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Single IgG IL-1–Related Receptor Controls TLR Responses in Differentiated Human Intestinal Epithelial Cells

(2010) Mohammed A. Khan et al.   JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

The Type III Secretion Effector NleE Inhibits NF-κB Activation

(2010) Chen Nadler et al.   PLoS Pathogens

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Stat3 Is a Negative Regulator of Intestinal Tumor Progression in ApcMin Mice

(2009) Monica Musteanu et al.   GASTROENTEROLOGY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Damage control in host-pathogen interactions

(2009) R. Medzhitov   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function

(2009) Xiaofei Gao et al.   PLoS Pathogens

Caspase-12 Modulates NOD Signaling and Regulates Antimicrobial Peptide Production and Mucosal Immunity

(2008) Philippe M. LeBlanc et al.   Cell Host & Microbe

Interleukin-1 Receptor Signaling Protects Mice from Lethal Intestinal Damage Caused by the Attaching and Effacing Pathogen Citrobacter rodentium

(2008) S. L. Lebeis et al.   INFECTION AND IMMUNITY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Decomposing health: tolerance and resistance to parasites in animals

(2008) L. Raberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Animal Defenses against Infectious Agents: Is Damage Control More Important Than Pathogen Control

(2008) Andrew F Read et al.   PLOS BIOLOGY

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY