The WxxxE effector EspT triggers expression of immune mediators in an Erk/JNK and NF-κB-dependent manner

Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF- B, Suppresses I B  Ubiquitination and Modulates Innate Immune Responses

(2014) G. Le Negrate et al.   JOURNAL OF IMMUNOLOGY

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

(2011) Jaclyn S. Pearson et al.   MOLECULAR MICROBIOLOGY

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

(2011) Alexander R. C. Wong et al.   MOLECULAR MICROBIOLOGY

IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7

(2011) Fengyi Wan et al.   NATURE IMMUNOLOGY

GM-CSF-Facilitated Dendritic Cell Recruitment and Survival Govern the Intestinal Mucosal Response to a Mouse Enteric Bacterial Pathogen

(2010) Yoshihiro Hirata et al.   Cell Host & Microbe

A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis

(2010) Na Dong et al.   EMBO JOURNAL

Metalloprotease type III effectors that specifically cleave JNK and NF-κB

(2010) Kobi Baruch et al.   EMBO JOURNAL

Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors

(2010) R. Bulgin et al.   INFECTION AND IMMUNITY

Inhibition of NF- B Signaling in Human Dendritic Cells by the Enteropathogenic Escherichia coli Effector Protein NleE

(2010) A. Vossenkamper et al.   JOURNAL OF IMMUNOLOGY

The Type III Secretion Effector NleE Inhibits NF-κB Activation

(2010) Chen Nadler et al.   PLoS Pathogens

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

(2010) Hayley J. Newton et al.   PLoS Pathogens

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

(2010) Hilo Yen et al.   PLoS Pathogens

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

(2009) Andreas J. Müller et al.   Cell Host & Microbe

EspM2 is a RhoA guanine nucleotide exchange factor

(2009) Ana Arbeloa et al.   CELLULAR MICROBIOLOGY

Distribution of espM and espT among enteropathogenic and enterohaemorrhagic Escherichia coli

(2009) A. Arbeloa et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The T3SS Effector EspT Defines a New Category of Invasive Enteropathogenic E. coli (EPEC) Which Form Intracellular Actin Pedestals

(2009) Richard Bulgin et al.   PLoS Pathogens

Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells

(2009) Vincent M. Bruno et al.   PLoS Pathogens

Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function

(2009) Xiaofei Gao et al.   PLoS Pathogens

Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens

(2008) Ana Arbeloa et al.   CELLULAR MICROBIOLOGY

EspJ of enteropathogenic and enterohaemorrhagic Escherichia coli inhibits opsono-phagocytosis

(2008) Oliver Marchès et al.   CELLULAR MICROBIOLOGY

EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42

(2008) Richard R. Bulgin et al.   CELLULAR MICROBIOLOGY

Salmonella enterica serovar Enteritidis dam mutant induces low NOS-2 and COX-2 expression in macrophages via attenuation of MAPK and NF-κB pathways

(2008) M. Cristina Cerquetti et al.   MICROBES AND INFECTION

GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

(2008) Atsuko Fukazawa et al.   PLoS Pathogens