Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

Protein Homeostasis as a Therapeutic Target for Diseases of Protein Conformation

(2013) Barbara Calamini et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The nascent polypeptide-associated complex is a key regulator of proteostasis

(2013) Janine Kirstein-Miles et al.   EMBO JOURNAL

Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism

(2013) G. J. Stout et al.   Molecular Systems Biology

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Why size matters – balancing mitochondrial dynamics in Alzheimer's disease

(2013) Brian DuBoff et al.   TRENDS IN NEUROSCIENCES

Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans

(2013) Eric L. Van Nostrand et al.   PLoS Genetics

The mystery of C. elegans aging: An emerging role for fat

(2012) Daniel Ackerman et al.   BIOESSAYS

MICS-1 interacts with mitochondrial ATAD-3 and modulates lifespan in C. elegans

(2012) Michael Hoffmann et al.   EXPERIMENTAL GERONTOLOGY

Biology of the Heat Shock Response and Protein Chaperones: Budding Yeast (Saccharomyces cerevisiae) as a Model System

(2012) J. Verghese et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis

(2012) J. He et al.   NUCLEIC ACIDS RESEARCH

Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways

(2012) David E. Shore et al.   PLoS Genetics

Noncanonical Amino Acid Labeling in Vivo to Visualize and Affinity Purify Newly Synthesized Proteins in Larval Zebrafish

(2011) Flora I. Hinz et al.   ACS Chemical Neuroscience

Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan

(2011) Pedro Reis-Rodrigues et al.   AGING CELL

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

(2011) Jenni Durieux et al.   CELL

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

(2011) Aric N. Rogers et al.   Cell Metabolism

Novel Roles of Caenorhabditis elegans Heterochromatin Protein HP1 and Linker Histone in the Regulation of Innate Immune Gene Expression

(2011) M. Studencka et al.   MOLECULAR AND CELLULAR BIOLOGY

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

Stable-isotope labeling with amino acids in nematodes

(2011) Mark Larance et al.   NATURE METHODS

The Stress of Protein Misfolding: From Single Cells to Multicellular Organisms

(2011) T. Gidalevitz et al.   Cold Spring Harbor Perspectives in Biology

Aging as an Event of Proteostasis Collapse

(2011) R. C. Taylor et al.   Cold Spring Harbor Perspectives in Biology

Caenorhabditis elegansas a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases

(2010) Janine Kirstein-Miles et al.   DEVELOPMENTAL DYNAMICS

Addressing Accuracy and Precision Issues in iTRAQ Quantitation

(2010) Natasha A. Karp et al.   MOLECULAR & CELLULAR PROTEOMICS

In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons

(2010) Daniela C Dieterich et al.   NATURE NEUROSCIENCE

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

(2010) Bart De Strooper   PHYSIOLOGICAL REVIEWS

HSF1-Controlled and Age-Associated Chaperone Capacity in Neurons and Muscle Cells of C. elegans

(2010) Andreas Kern et al.   PLoS One

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

(2009) Jeffrey M. Copeland et al.   CURRENT BIOLOGY

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

(2009) Marta Artal-Sanz et al.   NATURE

Cell-selective metabolic labeling of proteins

(2009) John T Ngo et al.   Nature Chemical Biology

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

(2009) A. Ben-Zvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

(2009) V. Rhein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA