Molecular and cellular pathogenesis of melanoma initiation and progression

MicroRNAs in malignant melanoma

(2013) Daniel Völler et al.   CLINICAL BIOCHEMISTRY

Aberrant hypomethylation of DDX43 promoter in myelodysplastic syndrome

(2012) Qin Chen et al.   BRITISH JOURNAL OF HAEMATOLOGY

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

(2012) M. B. Weiss et al.   CANCER RESEARCH

The Helicase HAGE Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Cell Proliferationin Vivo

(2012) Adam J. Linley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

(2012) Lawrence N Kwong et al.   NATURE MEDICINE

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Epithelial-Mesenchymal Transition (EMT) Regulatory Factor SLUG (SNAI2) Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion

(2012) Nina Fenouille et al.   PLoS One

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C

(2011) Elisa Penna et al.   EMBO JOURNAL

RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development

(2011) Frances V Fuller-Pace et al.   Future Oncology

miRNA-205 Suppresses Melanoma Cell Proliferation and Induces Senescence via Regulation of E2F1 Protein

(2011) Altaf A. Dar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA regulation of melanoma progression

(2011) Vanessa F. Bonazzi et al.   MELANOMA RESEARCH

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

(2011) Mitchell S Stark et al.   NATURE GENETICS

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny

(2011) Y Cheli et al.   ONCOGENE

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor

(2011) Glen M. Boyle et al.   Pigment Cell & Melanoma Research

High-Level Expression of Wild-Type p53 in Melanoma Cells is Frequently Associated with Inactivity in p53 Reporter Gene Assays

(2011) Roland Houben et al.   PLoS One

MicroRNA-193b Represses Cell Proliferation and Regulates Cyclin D1 in Melanoma

(2010) Jiamin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy

(2010) Stacey N Akers et al.   Future Oncology

The Cancer/Testis Antigen CAGE with Oncogenic Potential Stimulates Cell Proliferation by Up-regulating Cyclins D1 and E in an AP-1- and E2F-dependent Manner

(2010) Elaine Por et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer/Testis Antigen CAGE Exerts Negative Regulation on p53 Expression through HDAC2 and Confers Resistance to Anti-cancer Drugs

(2010) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma

(2010) Carmit Levy et al.   MOLECULAR CELL

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

(2010) Georgia Hatzivassiliou et al.   NATURE

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

Transcriptional control of melanoma metastasis: The importance of the tumor microenvironment

(2010) Russell R. Braeuer et al.   SEMINARS IN CANCER BIOLOGY

Role of miRNAs in the progression of malignant melanoma

(2009) D W Mueller et al.   BRITISH JOURNAL OF CANCER

Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice

(2009) Nathalie Dhomen et al.   CANCER CELL

Melanocytes in development and cancer

(2009) Audrey Uong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

(2008) E. L. Clark et al.   CANCER RESEARCH

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

(2008) Julia Schultz et al.   CELL RESEARCH

MicroRNA-221 and -222 pathway controls melanoma progression

(2008) Federica Felicetti et al.   Expert Review of Anticancer Therapy

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Integrin β3 expression is regulated by let-7a miRNA in malignant melanoma

(2008) D W Müller et al.   ONCOGENE

P68 RNA Helicase (DDX5) Alters Activity of Cis- and Trans-Acting Factors of the Alternative Splicing of H-Ras

(2008) Maria Camats et al.   PLoS One

Cancer Stem Cells: Lessons From Melanoma

(2008) Caterina La Porta   Stem Cell Reviews and Reports