Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice

Identification of Cellular Pathways of "Type 1," Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis

(2014) A. S. Haider et al.   JOURNAL OF IMMUNOLOGY

The heparanase/syndecan-1 axis in cancer: mechanisms and therapies

(2013) Vishnu C. Ramani et al.   FEBS Journal

Syndecan-1 and Heparanase

(2013) Shaoheng Zhang et al.   INFLAMMATORY BOWEL DISEASES

Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression

(2012) Miry Blich et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased expression of heparanase in symptomatic carotid atherosclerosis

(2012) C. Österholm et al.   ATHEROSCLEROSIS

Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice

(2012) J. Axelsson et al.   BLOOD

Heparanase enzyme in chronic inflammatory bowel disease and colon cancer

(2012) Esther Hermano et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

(2012) Eric P Schmidt et al.   NATURE MEDICINE

Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

(2012) Andrew Jarnicki et al.   Cell Division

Psoriasis

(2011) Gayathri K. Perera et al.   Annual Review of Pathology-Mechanisms of Disease

Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis

(2011) G. Rao et al.   DIABETOLOGIA

Heparanase Induces Signal Transducer and Activator of Transcription (STAT) Protein Phosphorylation

(2011) Victoria Cohen-Kaplan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

(2011) Immanuel Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated

(2011) Hamid Akbarshahi et al.   Journal of Translational Medicine

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

(2011) William R. Swindell et al.   PLoS One

Expression of cyclin D1 and p16 in psoriasis before and after phototherapy

(2010) M. Abou EL-Ela et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis

(2010) Judilyn Fuentes-Duculan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis: what we have learned from mouse models

(2010) Erwin F. Wagner et al.   Nature Reviews Rheumatology

Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis

(2010) Christopher E.M. Griffiths et al.   NEW ENGLAND JOURNAL OF MEDICINE

Key Role of Macrophages in the Pathogenesis of CD18 Hypomorphic Murine Model of Psoriasis

(2009) Honglin Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

Detection and Functional Analysis of Tumor Infiltrating T-Lymphocytes (TIL) in Liver Metastases from Colorectal Cancer

(2008) Philipp Wagner et al.   ANNALS OF SURGICAL ONCOLOGY

The expression of syndecan-1 in psoriatic epidermis

(2008) Davor Tomas et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis

(2008) Rachel W. Li et al.   ARTHRITIS AND RHEUMATISM

Heparanase Alters Arterial Structure, Mechanics, and Repair Following Endovascular Stenting in Mice

(2008) Aaron B. Baker et al.   CIRCULATION RESEARCH

Heparanase: One Molecule with Multiple Functions in Cancer Progression

(2008) Israel Vlodavsky et al.   CONNECTIVE TISSUE RESEARCH

TPA induction leads to a Th17-like response in transgenic K14/VEGF mice: a novel in vivo screening model of psoriasis

(2008) H. Hvid et al.   INTERNATIONAL IMMUNOLOGY

Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment

(2008) Ghada Abboud-Jarrous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases

(2007) Shigetoshi Sano et al.   JOURNAL OF DERMATOLOGICAL SCIENCE