The implications of viral reservoirs on the elite control of HIV-1 infection

Comprehensive analysis of unique cases with extraordinary control over HIV replication

(2012) D. Mendoza et al.   BLOOD

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding

(2012) Adjoa Smalls-Mantey et al.   JOURNAL OF VIROLOGY

Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs

(2012) Robert W. Buckheit et al.   Nature Communications

Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers

(2011) A. Saez-Cirion et al.   BLOOD

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21

(2011) Huabiao Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Circulating Monocytes Are Not a Major Reservoir of HIV-1 in Elite Suppressors

(2011) A. M. Spivak et al.   JOURNAL OF VIROLOGY

CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors

(2011) K. A. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy

(2011) Maria Salgado et al.   Retrovirology

Viral suppression of multiple escape mutants by de novo CD8+ T cell responses in a human immunodeficiency virus-1 Infected elite suppressor

(2011) Karen A O'Connell et al.   Retrovirology

Epidemiology and clinical characteristics of elite controllers

(2011) Jason F Okulicz et al.   Current Opinion in HIV and AIDS

Understanding animal models of elite control: windows on effective immune responses against immunodeficiency viruses

(2011) Philip A Mudd et al.   Current Opinion in HIV and AIDS

Functional Cure of SIVagm Infection in Rhesus Macaques Results in Complete Recovery of CD4+ T Cells and Is Reverted by CD8+ Cell Depletion

(2011) Ivona Pandrea et al.   PLoS Pathogens

Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART

(2011) Erin H. Graf et al.   PLoS Pathogens

Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+T Cells in HIV Elite Controllers

(2010) B. Julg et al.   CLINICAL INFECTIOUS DISEASES

Reduced Replication Capacity of NL4-3 Recombinant Viruses Encoding Reverse Transcriptase–Integrase Sequences From HIV-1 Elite Controllers

(2010) Zabrina L Brumme et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection

(2010) H. Mens et al.   JOURNAL OF VIROLOGY

Unstimulated Primary CD4+ T Cells from HIV-1-Positive Elite Suppressors Are Fully Susceptible to HIV-1 Entry and Productive Infection

(2010) S. A. Rabi et al.   JOURNAL OF VIROLOGY

Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

(2010) T. Miura et al.   JOURNAL OF VIROLOGY

Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus

(2010) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

(2010) Maria Salgado et al.   Retrovirology

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

The role of protective HCP5 and HLA-C associated polymorphisms in the control of HIV-1 replication in a subset of elite suppressors

(2009) Yefei Han et al.   AIDS

Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers

(2009) Olivier Lambotte et al.   AIDS

T Cell Dynamics and the Response to HAART in a Cohort of HIV‐1–Infected Elite Suppressors

(2009) Ahmad R. Sedaghat et al.   CLINICAL INFECTIOUS DISEASES

Spontaneous Control of Viral Replication during Primary HIV Infection: When Is “HIV Controller” Status Established?

(2009) Cécile Goujard et al.   CLINICAL INFECTIOUS DISEASES

Epidemiologic Characteristics and Natural History of HIV-1 Natural Viral Suppressors

(2009) Mohammad M Sajadi et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

(2009) A. Saez-Cirion et al.   JOURNAL OF IMMUNOLOGY

Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters

(2009) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Outcomes of Elite Controllers, Viremic Controllers, and Long‐Term Nonprogressors in the US Department of Defense HIV Natural History Study

(2009) Jason F. Okulicz et al.   JOURNAL OF INFECTIOUS DISEASES

Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4+ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy

(2009) T. P. Brennan et al.   JOURNAL OF VIROLOGY

Elite Suppressor–Derived HIV-1 Envelope Glycoproteins Exhibit Reduced Entry Efficiency and Kinetics

(2009) Kara G. Lassen et al.   PLoS Pathogens

Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection

(2008) Daniëlle van Manen et al.   AIDS

CD4+T Cell Depletion in an Untreated HIV Type 1–Infected Human Leukocyte Antigen–B*5801–Positive Patient with an Undetectable Viral Load

(2008) Adriana Andrade et al.   CLINICAL INFECTIOUS DISEASES

A Comparison of Viral Loads between HIV‐1–Infected Elite Suppressors and Individuals Who Receive Suppressive Highly Active Antiretroviral Therapy

(2008) Jason B. Dinoso et al.   CLINICAL INFECTIOUS DISEASES

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Characterization of Human Immunodeficiency Virus Type 1 in Elite Controllers: Lack of Gross Genetic Defects or Common Amino Acid Changes

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control

(2008) B. Emu et al.   JOURNAL OF VIROLOGY

Transmission of Human Immunodeficiency Virus Type 1 from a Patient Who Developed AIDS to an Elite Suppressor

(2008) J. R. Bailey et al.   JOURNAL OF VIROLOGY

Evidence of CD8+ T-Cell-Mediated Selective Pressure on Human Immunodeficiency Virus Type 1 nef in HLA-B*57+ Elite Suppressors

(2008) J. R. Bailey et al.   JOURNAL OF VIROLOGY

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy

(2008) H. Hatano et al.   JOURNAL OF VIROLOGY

HIV-1 Disease-Influencing Effects Associated with ZNRD1, HCP5 and HLA-C Alleles Are Attributable Mainly to Either HLA-A10 or HLA-B*57 Alleles

(2008) Gabriel Catano et al.   PLoS One

Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study

(2008) Cyril Dalmasso et al.   PLoS One

Relationship between T Cell Activation and CD4+T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

(2007) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES