Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

Rapid Up-Regulation and Granule-Independent Transport of Perforin to the Immunological Synapse Define a Novel Mechanism of Antigen-Specific CD8+ T Cell Cytotoxic Activity

(2009) G. Makedonas et al.   JOURNAL OF IMMUNOLOGY

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

(2009) A. Saez-Cirion et al.   JOURNAL OF IMMUNOLOGY

Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro

(2009) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Differential Neutralization of Human Immunodeficiency Virus (HIV) Replication in Autologous CD4 T Cells by HIV-Specific Cytotoxic T Lymphocytes

(2009) H. Chen et al.   JOURNAL OF VIROLOGY

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

(2009) S. A. Migueles et al.   JOURNAL OF VIROLOGY

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

(2008) A. L. Ferre et al.   BLOOD

Flow cytometric detection of perforin upregulation in human CD8 T cells

(2008) Adam R. Hersperger et al.   CYTOMETRY PART A

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

(2008) P. K. Chattopadhyay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control

(2008) B. Emu et al.   JOURNAL OF VIROLOGY

Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy

(2008) H. Hatano et al.   JOURNAL OF VIROLOGY

Phenotype and function of protective T cell immune responses in HIV

(2008) Michael R Betts et al.   Current Opinion in HIV and AIDS

Relationship between T Cell Activation and CD4+T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

(2007) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES