Comprehensive analysis of unique cases with extraordinary control over HIV replication

Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers

(2011) A. Saez-Cirion et al.   BLOOD

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21

(2011) Huabiao Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of HIV-1 Integration in Ex Vivo-Infected CD4 T Cells from Elite Controllers

(2011) M. J. Buzon et al.   JOURNAL OF VIROLOGY

CD4+ T Cells, Including Th17 and Cycling Subsets, Are Intact in the Gut Mucosa of HIV-1-Infected Long-Term Nonprogressors

(2011) E. J. Ciccone et al.   JOURNAL OF VIROLOGY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors

(2011) K. A. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control

(2011) Adam R Hersperger et al.   Current Opinion in HIV and AIDS

Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART

(2011) Erin H. Graf et al.   PLoS Pathogens

Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles

(2011) Stephen A. Migueles et al.   PLoS Pathogens

Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

(2010) Tae-Wook Chun et al.   AIDS

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+T Cells in HIV Elite Controllers

(2010) B. Julg et al.   CLINICAL INFECTIOUS DISEASES

Long-term Nonprogressive Disease Among Untreated HIV-Infected Individuals

(2010) Stephen A. Migueles et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Large Intestine as a Major Reservoir for Simian Immunodeficiency Virus in Macaques with Long‐Term, Nonprogressing Infection

(2010) Binhua Ling et al.   JOURNAL OF INFECTIOUS DISEASES

Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy

(2010) Steven A. Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

Unstimulated Primary CD4+ T Cells from HIV-1-Positive Elite Suppressors Are Fully Susceptible to HIV-1 Entry and Productive Infection

(2010) S. A. Rabi et al.   JOURNAL OF VIROLOGY

Spontaneous Control of Viral Replication during Primary HIV Infection: When Is “HIV Controller” Status Established?

(2009) Cécile Goujard et al.   CLINICAL INFECTIOUS DISEASES

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

(2009) A. Saez-Cirion et al.   JOURNAL OF IMMUNOLOGY

Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters

(2009) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Outcomes of Elite Controllers, Viremic Controllers, and Long‐Term Nonprogressors in the US Department of Defense HIV Natural History Study

(2009) Jason F. Okulicz et al.   JOURNAL OF INFECTIOUS DISEASES

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

(2009) S. A. Migueles et al.   JOURNAL OF VIROLOGY

Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels

(2009) E J Ciccone et al.   Mucosal Immunology

Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

(2008) A. L. Ferre et al.   BLOOD

A Comparison of Viral Loads between HIV‐1–Infected Elite Suppressors and Individuals Who Receive Suppressive Highly Active Antiretroviral Therapy

(2008) Jason B. Dinoso et al.   CLINICAL INFECTIOUS DISEASES

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy

(2008) Tae‐Wook Chun et al.   JOURNAL OF INFECTIOUS DISEASES

Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

(2008) N. A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy

(2008) H. Hatano et al.   JOURNAL OF VIROLOGY