Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN

The Chaperone-assisted E3 Ligase C Terminus of Hsc70-interacting Protein (CHIP) Targets PTEN for Proteasomal Degradation

(2012) Syed Feroj Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival

(2012) Chad R Schultz et al.   Molecular Cancer

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins

(2012) Benjamin Gibert et al.   PLoS One

HSP90 as a platform for the assembly of more effective cancer chemotherapy

(2011) Luke Whitesell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors

(2011) Adam Naguib et al.   BMC CANCER

Silencing hsp25/hsp27 Gene Expression Augments Proteasome Activity and Increases CD8+ T-Cell-Mediated Tumor Killing and Memory Responses

(2011) G. M. Nagaraja et al.   Cancer Prevention Research

Hsp27 silencing coordinately inhibits proliferation and promotes Fas-induced apoptosis by regulating the PEA-15 molecular switch

(2011) N Hayashi et al.   CELL DEATH AND DIFFERENTIATION

Different Conformations of Phosphatase and Tensin Homolog, Deleted on Chromosome 10 (PTEN) Protein within the Nucleus and Cytoplasm of Neurons

(2011) Vera L. Moncalero et al.   PLoS One

Roles of the N- and C-terminal sequences in Hsp27 self-association and chaperone activity

(2011) Barbara Lelj-Garolla et al.   PROTEIN SCIENCE

Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27)

(2010) Catherine Paul et al.   EXPERIMENTAL CELL RESEARCH

Regulation of PTEN Stability and Activity by Plk3

(2010) Dazhong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P-Cadherin and β-catenin are useful prognostic markers in breast cancer patients; β-catenin interacts with heat shock protein Hsp27

(2008) Mariel A. Fanelli et al.   CELL STRESS & CHAPERONES