The Chaperone-assisted E3 Ligase C Terminus of Hsc70-interacting Protein (CHIP) Targets PTEN for Proteasomal Degradation

Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis

(2011) Tao Xu et al.   CANCER SCIENCE

Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme

(2011) K H Oh et al.   CELL DEATH AND DIFFERENTIATION

WWP2 is an E3 ubiquitin ligase for PTEN

(2011) Subbareddy Maddika et al.   NATURE CELL BIOLOGY

PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells

(2010) Tao Tian et al.   CARCINOGENESIS

CHIP Promotes Human Telomerase Reverse Transcriptase Degradation and Negatively Regulates Telomerase Activity

(2010) Ji Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docking-dependent Ubiquitination of the Interferon Regulatory Factor-1 Tumor Suppressor Protein by the Ubiquitin Ligase CHIP

(2010) Vikram Narayan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E1A Interacts with Two Opposing Transcriptional Pathways To Induce Quiescent Cells into S Phase

(2010) J. Sha et al.   JOURNAL OF VIROLOGY

CHIP functions an E3 ubiquitin ligase of Runx1

(2009) Yu Shang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous Tumor Suppression Mediated by PTEN Involves Survivin Gene Silencing

(2009) M. Guha et al.   CANCER RESEARCH

X-linked Inhibitor of Apoptosis Protein (XIAP) Regulates PTEN Ubiquitination, Content, and Compartmentalization

(2009) Céline Van Themsche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress-dependent Daxx-CHIP Interaction Suppresses the p53 Apoptotic Program

(2009) Holly McDonough et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α

(2009) Weibo Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways

(2009) Masashi Kajiro et al.   NATURE CELL BIOLOGY

PTEN hamartoma tumor syndromes

(2008) Gideon M Blumenthal et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The nuclear affairs of PTEN

(2008) S. M. Planchon et al.   JOURNAL OF CELL SCIENCE

Post-translational regulation of PTEN

(2008) X Wang et al.   ONCOGENE

The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

(2008) F. Fouladkou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool

(2008) P. Reddy et al.   SCIENCE