ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7
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Title
ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7
Authors
Keywords
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Journal
CELL DEATH AND DIFFERENTIATION
Volume 21, Issue 8, Pages 1275-1289
Publisher
Springer Nature
Online
2014-04-25
DOI
10.1038/cdd.2014.48
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Note: Only part of the references are listed.- mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
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- (2012) Jiezhong Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The expression and prognosis of FOXO3a and Skp2 in human ovarian cancer
- (2012) Mudan Lu et al. MEDICAL ONCOLOGY
- Effect of ARHI on lung cancer cell proliferation, apoptosis and invasion in vitro
- (2012) Xiaohong Wu et al. MOLECULAR BIOLOGY REPORTS
- Class IA Phosphatidylinositol 3-Kinase p110α Regulates Phagosome Maturation
- (2012) Emily P. Thi et al. PLoS One
- Effects of ARHI on cell cycle progression and apoptosis levels of breast cancer cells
- (2012) Ying Li et al. TUMOR BIOLOGY
- Study of the PDK1/AKT signaling pathway using selective PDK1 inhibitors, HCS, and enhanced biochemical assays
- (2011) Alexandra Hofler et al. ANALYTICAL BIOCHEMISTRY
- Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy
- (2011) Min-Yu Chen et al. CANCER
- Deciphering the Role of Forkhead Transcription Factors in Cancer Therapy
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- Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
- (2011) Ian G. Ganley et al. MOLECULAR CELL
- The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways
- (2011) D B Badgwell et al. ONCOGENE
- Met Receptor: A Moving Target
- (2011) M. J. Clague Science Signaling
- Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action
- (2010) Subhendu Mukherjee et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
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- (2010) Y. Chen et al. Cancer Prevention Research
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- Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation
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- FoxO Transcription Factors Promote Autophagy in Cardiomyocytes
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- ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
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- Altered mechanosensitive properties of vagal afferent fibers innervating the stomach following gastric surgery in rats
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- The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
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- OncogenicHRASmutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome
- (2008) Georg Rosenberger et al. HUMAN MUTATION
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- ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
- (2008) Jer-Yen Yang et al. NATURE CELL BIOLOGY
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