Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout

Molecular mechanisms of hepatic apoptosis

(2014) K Wang   Cell Death & Disease

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

(2013) F J Cubero et al.   CELL DEATH AND DIFFERENTIATION

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

(2013) Filip Van Hauwermeiren et al.   JOURNAL OF CLINICAL INVESTIGATION

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury

(2011) Christian Liedtke et al.   GASTROENTEROLOGY

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

(2011) Marion C. Bonnet et al.   IMMUNITY

TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation

(2011) Françoise Meylan et al.   IMMUNOLOGICAL REVIEWS

Cell death and hepatocarcinogenesis: Dysregulation of apoptosis signaling pathways

(2011) Jorn Markus Schattenberg et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Obesity, inflammation, and liver cancer

(2011) Beicheng Sun et al.   JOURNAL OF HEPATOLOGY

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

(2011) Patrick-Simon Welz et al.   NATURE

Functional complementation between FADD and RIP1 in embryos and lymphocytes

(2011) Haibing Zhang et al.   NATURE

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Oligodendrocyte-Specific FADD Deletion Protects Mice from Autoimmune-Mediated Demyelination

(2010) C. Mc Guire et al.   JOURNAL OF IMMUNOLOGY

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

(2009) Johannes Haybaeck et al.   CANCER CELL

Hepatocyte-specific NEMO deletion promotes NK/NKT cell– and TRAIL-dependent liver damage

(2009) Naiara Beraza et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

(2009) Mohamed IF Shariff et al.   Expert Review of Gastroenterology & Hepatology

TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development

(2008) Anne Grosse-Wilde et al.   JOURNAL OF CLINICAL INVESTIGATION

NF-κB signaling, liver disease and hepatoprotective agents

(2008) B Sun et al.   ONCOGENE

IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver

(2008) T. Luedde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA