TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation

Triggering of TNFRSF25 promotes CD8+ T-cell responses and anti-tumor immunity

(2011) Tomasz J. Slebioda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Expression of TNFRSF25 on conventional T cells and Tregs

(2011) Vadim Y. Taraban et al.   JOURNAL OF CLINICAL INVESTIGATION

The Adaptor Protein TRADD Is Essential for TNF-Like Ligand 1A/Death Receptor 3 Signaling

(2011) Y. L. Pobezinskaya et al.   JOURNAL OF IMMUNOLOGY

Constitutive TL1A (TNFSF15) Expression on Lymphoid or Myeloid Cells Leads to Mild Intestinal Inflammation and Fibrosis

(2011) David Q. Shih et al.   PLoS One

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation

(2010) Gareth W. Jones et al.   FASEB JOURNAL

TL1A Selectively Enhances IL-12/IL-18-Induced NK Cell Cytotoxicity against NK-Resistant Tumor Targets

(2010) Stephanie C. Heidemann et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation

(2010) Taylor H. Schreiber et al.   JOURNAL OF CLINICAL INVESTIGATION

The TNF-Like Protein 1A-Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro

(2010) J. E. McLaren et al.   JOURNAL OF IMMUNOLOGY

Age-Dependent Maintenance of Motor Controland Corticostriatal Innervation by Death Receptor 3

(2010) J. P. Twohig et al.   JOURNAL OF NEUROSCIENCE

Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

(2010) V Y Taraban et al.   Mucosal Immunology

The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation

(2010) F Meylan et al.   Mucosal Immunology

Role of TL1A in the Pathogenesis of Rheumatoid Arthritis

(2009) J. Zhang et al.   JOURNAL OF IMMUNOLOGY

IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein

(2009) Kathrin S. Michelsen et al.   PLoS One

Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis

(2008) Giorgos Bamias et al.   CLINICAL IMMUNOLOGY

TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation

(2008) Hidetoshi Takedatsu et al.   GASTROENTEROLOGY

The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

(2008) Françoise Meylan et al.   IMMUNITY

Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation

(2008) Lei Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

(2008) Melanie Jane Bull et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease

(2008) Bhanu P. Pappu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

T Cells and NKT Cells in the Pathogenesis of Asthma

(2007) Everett H. Meyer et al.   Annual Review of Medicine