Targeting the Y/CCAAT box in cancer: YB-1 (YBX1) or NF-Y?

YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention

(2015) Alastair H. Davies et al.   Oncotarget

Sequence-Specific Transcription Factor NF-Y Displays Histone-like DNA Binding and H2B-like Ubiquitination

(2013) Marco Nardini et al.   CELL

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

(2012) J. Wang et al.   GENOME RESEARCH

MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition

(2012) A Astanehe et al.   ONCOGENE

The Short Isoform of NF-YA Belongs to the Embryonic Stem Cell Transcription Factor Circuitry

(2012) Diletta Dolfini et al.   STEM CELLS

Reduced proliferation and enhanced migration: Two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1

(2011) Valentina Evdokimova et al.   CELL CYCLE

A perspective of promoter architecture from the CCAAT box

(2011) Diletta Dolfini et al.   CELL CYCLE

NF-Y and the transcriptional activation of CCAAT promoters

(2011) Diletta Dolfini et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters

(2011) Adalberto Costessi et al.   EMBO JOURNAL

Role for Class I histone deacetylases in multidrug resistance

(2011) Yichun Xu et al.   EXPERIMENTAL CELL RESEARCH

YB-1, the E2F Pathway, and Regulation of Tumor Cell Growth

(2011) Annette Lasham et al.   JNCI-Journal of the National Cancer Institute

Genome wide study of NF-Y type CCAAT boxes in unidirectional and bidirectional promoters in human and mouse

(2011) Antti Häkkinen et al.   JOURNAL OF THEORETICAL BIOLOGY

A chromatin-modifying function of JNK during stem cell differentiation

(2011) Vijay K Tiwari et al.   NATURE GENETICS

Specific inhibition of NF-Y subunits triggers different cell proliferation defects

(2011) Paolo Benatti et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic cold shock domain proteins: highly versatile regulators of gene expression

(2010) Marija Mihailovich et al.   BIOESSAYS

TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells

(2010) A. D. Domashenko et al.   BLOOD

Histone Methyltransferase MLL1 Regulates MDR1 Transcription and Chemoresistance

(2010) H. Huo et al.   CANCER RESEARCH

Y-Box Binding Protein-1 Induces the Expression ofCD44andCD49fLeading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance

(2010) Karen To et al.   CANCER RESEARCH

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

(2010) S Sengupta et al.   ONCOGENE

Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells

(2010) E. Camilla Forsberg et al.   PLoS One

Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells

(2010) Karsten Jürchott et al.   PLoS Genetics

Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition

(2009) Valentina Evdokimova et al.   CANCER CELL

Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers

(2009) Kazunori Yamanaka et al.   GENOMICS

Revealing Global Regulatory Perturbations across Human Cancers

(2009) Hani Goodarzi et al.   MOLECULAR CELL

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

(2009) Debashish Ray et al.   NATURE BIOTECHNOLOGY

Allegro: Analyzing expression and sequence in concert to discover regulatory programs

(2009) Yonit Halperin et al.   NUCLEIC ACIDS RESEARCH

The transcriptional induction of PIK3CA in tumor cells is dependent on the oncoprotein Y-box binding protein-1

(2009) A Astanehe et al.   ONCOGENE

Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells

(2009) M R Finkbeiner et al.   ONCOGENE

Molecular Signatures of Prostate Stem Cells Reveal Novel Signaling Pathways and Provide Insights into Prostate Cancer

(2009) Roy Blum et al.   PLoS One

Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells

(2008) Atsushi Niida et al.   BMC BIOINFORMATICS

Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer

(2008) Mads Thomassen et al.   BMC CANCER

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Splicing, transcription, and chromatin: a ménage à trois

(2008) Eric Allemand et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Systematic functional characterization of cis-regulatory motifs in human core promoters

(2008) S. Sinha et al.   GENOME RESEARCH

The Histone-Like NF-Y Is a Bifunctional Transcription Factor

(2008) M. Ceribelli et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

(2008) R. Chattopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response

(2008) Paolo Benatti et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes

(2008) Brian D. Reed et al.   PLoS Genetics