Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

(2009) M. Pajic et al.   CANCER RESEARCH

Acetylation of Apurinic/Apyrimidinic Endonuclease-1 Regulates Helicobacterpylori-Mediated Gastric Epithelial Cell Apoptosis

(2009) Asima Bhattacharyya et al.   GASTROENTEROLOGY

Impairment of APE1 Function Enhances Cellular Sensitivity to Clinically Relevant Alkylators and Antimetabolites

(2009) D. R. McNeill et al.   MOLECULAR CANCER RESEARCH

Apurinic/Apyrimidinic Endonuclease 1 Alters Estrogen Receptor Activity and Estrogen-Responsive Gene Expression

(2009) Carol D. Curtis et al.   MOLECULAR ENDOCRINOLOGY

SIRT1 deacetylates APE1 and regulates cellular base excision repair

(2009) Tohru Yamamori et al.   NUCLEIC ACIDS RESEARCH

Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53–MDM2 signaling pathway

(2009) C S Busso et al.   ONCOGENE

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells

(2009) Carlo Vascotto et al.   PROTEOMICS

Going Ape as an Approach to Cancer Therapeutics

(2008) Aditi Bapat et al.   ANTIOXIDANTS & REDOX SIGNALING

Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

(2008) Kishor K. Bhakat et al.   ANTIOXIDANTS & REDOX SIGNALING

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING

Implications of Apurinic/Apyrimidinic Endonuclease in Reactive Oxygen Signaling Response after Cisplatin Treatment of Dorsal Root Ganglion Neurons

(2008) Y. Jiang et al.   CANCER RESEARCH

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

(2008) Damiano Fantini et al.   FREE RADICAL RESEARCH

Unusual Role of a Cysteine Residue in Substrate Binding and Activity of Human AP-Endonuclease 1

(2008) Anil K. Mantha et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

(2008) R. Chattopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

A new APE1/Ref-1-dependent pathway leading to reduction of NF- B and AP-1, and activation of their DNA-binding activity

(2008) K. Ando et al.   NUCLEIC ACIDS RESEARCH