Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation

mRNP granules

(2014) J Ross Buchan   RNA Biology

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

(2013) K. Cramer-Morales et al.   BLOOD

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

(2012) M. Nieborowska-Skorska et al.   BLOOD

Unfolding tyrosine kinase inhibitor sensitivity in chronic myeloid leukemia

(2012) Danilo Perrotti et al.   CELL CYCLE

The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells

(2012) Monika Kusio-Kobialka et al.   CELL CYCLE

Dynamic Coregulatory Complex Containing BRCA1, E2F1 and CtIP Controls ATM Transcription

(2012) Cristian Moiola et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of BRCA1 in DNA double-strand repair: Past and present

(2012) Kevin W. Caestecker et al.   EXPERIMENTAL CELL RESEARCH

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation

(2011) Kiyoshi Masuda et al.   EMBO JOURNAL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro and in vivo

(2011) K Schuster et al.   Blood Cancer Journal

miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts

(2010) Anna M. Eiring et al.   CELL

Expression of Oncogenic Kinase Bcr-Abl Impairs Mitotic Checkpoint and Promotes Aberrant Divisions and Resistance to Microtubule-Targeting Agents

(2010) K. Wolanin et al.   MOLECULAR CANCER THERAPEUTICS

TIAR and TIA-1 mRNA-Binding Proteins Co-aggregate under Conditions of Rapid Oxygen Decline and Extreme Hypoxia and Suppress the HIF-1  Pathway

(2010) O. R. Gottschald et al.   Journal of Molecular Cell Biology

The role of BRCA1 in DNA damage response

(2010) Jiaxue Wu et al.   Protein & Cell

Posttranscriptional Regulation of the Breast Cancer Susceptibility Gene BRCA1 by the RNA Binding Protein HuR

(2008) J. M. Saunus et al.   CANCER RESEARCH

The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

(2008) Yi Wen Kong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis

(2007) A. M. Eiring et al.   BLOOD