mRNP granules

MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis

(2014) Xiaojie Zhang et al.   Autophagy

Is there quality control of localized mRNAs?

(2014) Robert Walters et al.   JOURNAL OF CELL BIOLOGY

mRNA localization to Pbodies in yeast is biphasic with many mRNAs captured in a late Bfr1pdependent wave

(2014) C. E. Simpson et al.   JOURNAL OF CELL SCIENCE

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse

(2014) H. Y. Park et al.   SCIENCE

Molecular Mechanisms of RNA Interference

(2013) Ross C. Wilson et al.   Annual Review of Biophysics

Quality control systems for aberrant mRNAs induced by aberrant translation elongation and termination

(2013) Toshifumi Inada   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum

(2013) Matthew Thomas et al.   BRAIN

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

(2013) Mani Ramaswami et al.   CELL

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Coordination of Translational Control and Protein Homeostasis during Severe Heat Stress

(2013) Valeria Cherkasov et al.   CURRENT BIOLOGY

Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis

(2013) P. S. Estes et al.   Disease Models & Mechanisms

mRNA cycles through hypoxia-induced stress granules in live Drosophila embryonic muscles

(2013) Annelies M.A. van der Laan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules

(2013) Kyota Yasuda et al.   JOURNAL OF CELL BIOLOGY

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

(2013) Hyung-Jun Kim et al.   NATURE GENETICS

The P Body Protein Dcp1a Is Hyper-phosphorylated during Mitosis

(2013) Adva Aizer et al.   PLoS One

Structural organization of the polysomes adjacent to mammalian processing bodies (P-bodies)

(2013) Nicolas Cougot et al.   RNA Biology

Specificity factors in cytoplasmic polyadenylation

(2013) Amanda Charlesworth et al.   Wiley Interdisciplinary Reviews-RNA

Regulation of stress granules and P-bodies during RNA virus infection

(2013) Richard E. Lloyd   Wiley Interdisciplinary Reviews-RNA

Microtubule-based motor-mediated mRNA localization inDrosophilaoocytes and embryos

(2012) Imre Gaspar   BIOCHEMICAL SOCIETY TRANSACTIONS

TDP-43 aggregation in neurodegeneration: Are stress granules the key?

(2012) Colleen M. Dewey et al.   BRAIN RESEARCH

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Paraspeckle nuclear bodies—useful uselessness?

(2012) Shinichi Nakagawa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells

(2012) Ippei Nagamori et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of the Eukaryotic Translation Initiation Factor 4E-Transporter (4E-T) by c-Jun N-Terminal Kinase Promotes Stress-Dependent P-Body Assembly

(2012) M. Cargnello et al.   MOLECULAR AND CELLULAR BIOLOGY

Transient Sequestration of TORC1 into Stress Granules during Heat Stress

(2012) Terunao Takahara et al.   MOLECULAR CELL

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

Neuronal mRNAs travel singly into dendrites

(2012) M. Batish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Fragile X Mental Retardation Protein granules formation and dynamics in Drosophila

(2012) C. Gareau et al.   Biology Open

Hsp90 is involved in the formation of P-bodies and stress granules

(2011) Ken Matsumoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nuage morphogenesis becomes more complex: two translocation pathways and two forms of nuage coexist in Drosophila germline syncytia

(2011) Mariusz K. Jaglarz et al.   CELL AND TISSUE RESEARCH

MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline

(2011) Toshiaki Watanabe et al.   DEVELOPMENTAL CELL

piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling

(2011) Huiyan Huang et al.   DEVELOPMENTAL CELL

Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers

(2011) Martin Mikl et al.   EMBO REPORTS

TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

(2011) Tao Zhang et al.   HUMAN MOLECULAR GENETICS

PGL proteins self associate and bind RNPs to mediate germ granule assembly inC. elegans

(2011) Momoyo Hanazawa et al.   JOURNAL OF CELL BIOLOGY

c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies

(2011) Katharina Rzeczkowski et al.   JOURNAL OF CELL BIOLOGY

Dynamic association-dissociation and harboring of endogenous mRNAs in stress granules

(2011) J. Zhang et al.   JOURNAL OF CELL SCIENCE

Cytoplasmic mRNP granules at a glance

(2011) S. L. Erickson et al.   JOURNAL OF CELL SCIENCE

Local RNA Translation at the Synapse and in Disease

(2011) L. Liu-Yesucevitz et al.   JOURNAL OF NEUROSCIENCE

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

RNA Granules in Germ Cells

(2011) E. Voronina et al.   Cold Spring Harbor Perspectives in Biology

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

(2011) Zhihui Sun et al.   PLOS BIOLOGY

The chemotherapeutic agent bortezomib induces the formation of stress granules

(2010) Marie-Josée Fournier et al.   Cancer Cell International

RNA granules: The good, the bad and the ugly

(2010) María Gabriela Thomas et al.   CELLULAR SIGNALLING

Perinuclear P granules are the principal sites of mRNA export in adult C. elegans germ cells

(2010) U. Sheth et al.   DEVELOPMENT

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

(2010) Daryl A. Bosco et al.   HUMAN MOLECULAR GENETICS

Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay inSaccharomyces cerevisiae

(2010) Je-Hyun Yoon et al.   JOURNAL OF CELL BIOLOGY

TDP-43 Mediates Degeneration in a Novel Drosophila Model of Disease Caused by Mutations in VCP/p97

(2010) G. P. Ritson et al.   JOURNAL OF NEUROSCIENCE

Dendritically Localized Transcripts Are Sorted into Distinct Ribonucleoprotein Particles That Display Fast Directional Motility along Dendrites of Hippocampal Neurons

(2010) F. Tubing et al.   JOURNAL OF NEUROSCIENCE

Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing Bodies

(2010) S. Ozgur et al.   MOLECULAR AND CELLULAR BIOLOGY

Decapping Activators in Saccharomyces cerevisiae Act by Multiple Mechanisms

(2010) Tracy Nissan et al.   MOLECULAR CELL

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

(2010) Andrew C. Elden et al.   NATURE

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Multimerization of Staufen1 in live cells

(2010) C. Martel et al.   RNA

Regulation of mRNA decapping

(2010) You Li et al.   Wiley Interdisciplinary Reviews-RNA

Selective autophagic degradation of maternally-loaded germline P granule components in somatic cells duringC. elegansembryogenesis

(2009) Yu Zhao et al.   Autophagy

SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans

(2009) Yuxia Zhang et al.   CELL

mRNA Localization: Gene Expression in the Spatial Dimension

(2009) Kelsey C. Martin et al.   CELL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Translational control from head to tail

(2009) Rachel Groppo et al.   CURRENT OPINION IN CELL BIOLOGY

A Genomewide RNAi Screen for Genes That Affect the Stability, Distribution and Function of P Granules in Caenorhabditis elegans

(2009) Dustin L. Updike et al.   GENETICS

Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1Translation

(2009) Xian Jin Lian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

(2009) Brian S. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in theDrosophilagermline

(2009) Ai Khim Lim et al.   JOURNAL OF CELL BIOLOGY

Dynein and kinesin regulate stress-granule and P-body dynamics

(2009) M. Loschi et al.   JOURNAL OF CELL SCIENCE

Uncoupling Stress Granule Assembly and Translation Initiation Inhibition

(2009) Sophie Mokas et al.   MOLECULAR BIOLOGY OF THE CELL

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Temporally Regulated Traffic of HuR and Its Associated ARE-Containing mRNAs from the Chromatoid Body to Polysomes during Mouse Spermatogenesis

(2009) Mai Nguyen Chi et al.   PLoS One

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization

(2009) Y. Kirino et al.   RNA

Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice

(2009) Alexei A. Aravin et al.   PLoS Genetics

Translational control in early development: CPEB, P-bodies and germinal granules

(2008) Nancy Standart et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos

(2008) Christopher M. Gallo et al.   DEVELOPMENTAL BIOLOGY

Regulation of stress granule dynamics by Grb7 and FAK signalling pathway

(2008) Nien-Pei Tsai et al.   EMBO JOURNAL

Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP

(2008) Bastian Linder et al.   HUMAN MOLECULAR GENETICS

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

(2008) I. Goulet et al.   HUMAN MOLECULAR GENETICS

Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) duringCaenorhabditis elegansoogenesis

(2008) Peter R. Boag et al.   JOURNAL OF CELL BIOLOGY

P bodies promote stress granule assembly inSaccharomyces cerevisiae

(2008) J. Ross Buchan et al.   JOURNAL OF CELL BIOLOGY

A role for Q/N-rich aggregation-prone regions in P-body localization

(2008) M. A. M. Reijns et al.   JOURNAL OF CELL SCIENCE

Dynamic Interaction between P-Bodies and Transport Ribonucleoprotein Particles in Dendrites of Mature Hippocampal Neurons

(2008) M. Zeitelhofer et al.   JOURNAL OF NEUROSCIENCE

Multiplexed Dendritic Targeting of α Calcium Calmodulin-dependent Protein Kinase II, Neurogranin, and Activity-regulated Cytoskeleton-associated Protein RNAs by the A2 Pathway

(2008) Yuanzheng Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Translationally Repressed mRNA Transiently Cycles through Stress Granules during Stress

(2008) Stephanie Mollet et al.   MOLECULAR BIOLOGY OF THE CELL

PRG-1 and 21U-RNAs Interact to Form the piRNA Complex Required for Fertility in C. elegans

(2008) Pedro J. Batista et al.   MOLECULAR CELL

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

Lithium delays progression of amyotrophic lateral sclerosis

(2008) F. Fornai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body

(2008) W. Chang et al.   RNA

Simultaneous Transport of Different Localized mRNA Species Revealed by Live-Cell Imaging

(2008) Susanne Lange et al.   TRAFFIC

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES