Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

An SCF complex containing Fbxl12 mediates DNA damage-induced Ku80 ubiquitylation

(2013) Lisa Postow et al.   CELL CYCLE

Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling

(2013) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

(2012) Moumita Chaki et al.   CELL

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

(2012) Mallikarjun Patil et al.   CELL CYCLE

Cell cycle regulation by the NEK family of protein kinases

(2012) A. M. Fry et al.   JOURNAL OF CELL SCIENCE

Nek4 Regulates Entry into Replicative Senescence and the Response to DNA Damage in Human Fibroblasts

(2012) C. L. Nguyen et al.   MOLECULAR AND CELLULAR BIOLOGY

NEK1 Mutations Cause Short-Rib Polydactyly Syndrome Type Majewski

(2011) Christian Thiel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chromatin dynamics and the repair of DNA double strand breaks

(2011) Ye Xu et al.   CELL CYCLE

Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR

(2011) Yumay Chen et al.   CELL CYCLE

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

(2011) Navjotsingh Pabla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nek1 and TAZ Interact to Maintain Normal Levels of Polycystin 2

(2011) H. Yim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

(2011) Yumay Chen et al.   Molecular Cancer

Physiological Relevance of Cell Cycle Kinases

(2011) Marcos Malumbres   PHYSIOLOGICAL REVIEWS

Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

(2011) N. Pabla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NEK11−Linking CHK1 and CDC25A in DNA damage checkpoint signaling

(2010) Claus Storgaard Sørensen et al.   CELL CYCLE

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

The NIMA-related kinase NEK1 cycles through the nucleus

(2009) Laura K. Hilton et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC

(2009) Daniel C. F. Lanza et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint

(2009) Marina Melixetian et al.   NATURE CELL BIOLOGY

The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis

(2008) Mark C White et al.   BMC CELL BIOLOGY

Ku is involved in cell growth, DNA replication and G1-S transition

(2008) E. Rampakakis et al.   JOURNAL OF CELL SCIENCE