The RNA editing enzymes ADARs: mechanism of action and human disease

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma

(2013) Y.-R. Qin et al.   CANCER RESEARCH

The Long and Short of MicroRNA

(2013) Luke A. Yates et al.   CELL

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2delivery to motor neurons

(2013) Takenari Yamashita et al.   EMBO Molecular Medicine

ADAR Enzyme and miRNA Story: A Nucleotide that Can Make the Difference

(2013) Sara Tomaselli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

(2013) Leilei Chen et al.   NATURE MEDICINE

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing

(2013) M. F. Montiel-Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA editing regulates transposon-mediated heterochromatic gene silencing

(2013) Yiannis A. Savva et al.   Nature Communications

Systematic identification of edited microRNAs in the human brain

(2012) S. Alon et al.   GENOME RESEARCH

Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells

(2012) Yukti Choudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Accurate identification of human Alu and non-Alu RNA editing sites

(2012) Gokul Ramaswami et al.   NATURE METHODS

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

ADARs: allies or enemies? The importance of A-to-I RNA editing in human disease: from cancer to HIV-1

(2011) Angela Gallo et al.   BIOLOGICAL REVIEWS

A-to-I RNA editing: The “ADAR” side of human cancer

(2011) Federica Galeano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2

(2010) Hitoshi Aizawa et al.   ACTA NEUROPATHOLOGICA

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

(2010) T. Hideyama et al.   JOURNAL OF NEUROSCIENCE

AMPA receptor-mediated neuronal death in sporadic ALS

(2010) Shin Kwak et al.   NEUROPATHOLOGY

Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide

(2010) Nicole T. Schirle et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Editing independent effects of ADARs on the miRNA/siRNA pathways

(2009) Bret S E Heale et al.   EMBO JOURNAL

ADAR1 is required for hematopoietic progenitor cell survival via RNA editing

(2009) R. XuFeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down-regulation of RNA Editing in Pediatric Astrocytomas

(2008) Caterina Cenci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond DNA: RNA Editing and Steps Toward Alu Exonization in Primates

(2008) Maren Möller-Krull et al.   JOURNAL OF MOLECULAR BIOLOGY

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

Frequency and fate of microRNA editing in human brain

(2008) Y. Kawahara et al.   NUCLEIC ACIDS RESEARCH