ADAR Enzyme and miRNA Story: A Nucleotide that Can Make the Difference

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing

(2013) T. Lei et al.   JOURNAL OF GENERAL VIROLOGY

ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding

(2013) Q. Wang et al.   RNA

Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs

(2012) C. Vesely et al.   GENOME RESEARCH

A-to-I editing of microRNAs in the mammalian brain increases during development

(2012) Y. Ekdahl et al.   GENOME RESEARCH

Systematic identification of edited microRNAs in the human brain

(2012) S. Alon et al.   GENOME RESEARCH

Effects of ADARs on small RNA processing pathways in C. elegans

(2012) M. B. Warf et al.   GENOME RESEARCH

Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells

(2012) Yukti Choudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

(2012) Zhiyu Peng et al.   NATURE BIOTECHNOLOGY

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

Canonical A-to-I and C-to-U RNA Editing Is Enriched at 3′UTRs and microRNA Target Sites in Multiple Mouse Tissues

(2012) Tongjun Gu et al.   PLoS One

c-Jun Amino-Terminal Kinase-1 Mediates Glucose-Responsive Upregulation of the RNA Editing Enzyme ADAR2 in Pancreatic Beta-Cells

(2012) Liu Yang et al.   PLoS One

Mechanistic insights into editing-site specificity of ADARs

(2012) A. Kuttan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tudor-SN and ADAR1 are components of cytoplasmic stress granules

(2012) R. Weissbach et al.   RNA

Epigenetic Regulation by Long Noncoding RNAs

(2012) J. T. Lee   SCIENCE

miRNA regulates noncoding RNA: a noncanonical function model

(2012) Xi Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

ADARs: allies or enemies? The importance of A-to-I RNA editing in human disease: from cancer to HIV-1

(2011) Angela Gallo et al.   BIOLOGICAL REVIEWS

Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system

(2011) Rui Tang et al.   CELL RESEARCH

A-to-I RNA editing: The “ADAR” side of human cancer

(2011) Federica Galeano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Viruses, microRNAs, and Host Interactions

(2010) Rebecca L. Skalsky et al.   Annual Review of Microbiology

DARNED: a DAtabase of RNa EDiting in humans

(2010) A. Kiran et al.   BIOINFORMATICS

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Cross-mapping and the identification of editing sites in mature microRNAs in high-throughput sequencing libraries

(2010) M. J.L. de Hoon et al.   GENOME RESEARCH

Human BLCAP transcript: new editing events in normal and cancerous tissues

(2010) Federica Galeano et al.   INTERNATIONAL JOURNAL OF CANCER

Editing of Epstein-Barr Virus-encoded BART6 MicroRNAs Controls Their Dicer Targeting and Consequently Affects Viral Latency

(2010) Hisashi Iizasa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome

(2010) Masayuki Sakurai et al.   Nature Chemical Biology

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Editing independent effects of ADARs on the miRNA/siRNA pathways

(2009) Bret S E Heale et al.   EMBO JOURNAL

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

(2009) H. Wahlstedt et al.   GENOME RESEARCH

ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication

(2009) G. Clerzius et al.   JOURNAL OF VIROLOGY

RNA-Regulated Interaction of Transportin-1 and Exportin-5 with the Double-Stranded RNA-Binding Domain Regulates Nucleocytoplasmic Shuttling of ADAR1

(2009) J. Fritz et al.   MOLECULAR AND CELLULAR BIOLOGY

Viral and cellular messenger RNA targets of viral microRNAs

(2009) Bryan R. Cullen   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a selective nuclear import signal in adenosine deaminases acting on RNA

(2009) Stefan Maas et al.   NUCLEIC ACIDS RESEARCH

Novel Exon of Mammalian ADAR2 Extends Open Reading Frame

(2009) Stefan Maas et al.   PLoS One

Down-regulation of RNA Editing in Pediatric Astrocytomas

(2008) Caterina Cenci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Primary microRNA transcripts are processed co-transcriptionally

(2008) Mariangela Morlando et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Frequency and fate of microRNA editing in human brain

(2008) Y. Kawahara et al.   NUCLEIC ACIDS RESEARCH

The Mechanism Selecting the Guide Strand from Small RNA Duplexes is Different Among Argonaute Proteins

(2008) Atsushi Takeda et al.   PLANT AND CELL PHYSIOLOGY

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5′-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon

(2008) Cyril X. George et al.   VIROLOGY

Intronic Alus Influence Alternative Splicing

(2008) Galit Lev-Maor et al.   PLoS Genetics