Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Interleukin-22 Induces Interleukin-18 Expression from Epithelial Cells during Intestinal Infection

(2015) Melba Muñoz et al.   IMMUNITY

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4+ T cells

(2015) M. R. Hepworth et al.   SCIENCE

Development and regulation of RORγt+ innate lymphoid cells

(2014) Sascha Cording et al.   FEBS LETTERS

Innate Lymphoid Cells in Inflammation and Immunity

(2014) Andrew N.J. McKenzie et al.   IMMUNITY

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

(2014) Christopher J. Oliphant et al.   IMMUNITY

Anatomical localization of commensal bacteria in immune cell homeostasis and disease

(2014) Thomas C. Fung et al.   IMMUNOLOGICAL REVIEWS

Regulation of intestinal health and disease by innate lymphoid cells

(2014) G. F. Sonnenberg   INTERNATIONAL IMMUNOLOGY

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis

(2014) Mario Noti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The intestinal epithelium is an integral component of a communications network

(2014) Martin F. Kagnoff   JOURNAL OF CLINICAL INVESTIGATION

Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells

(2014) E Macho-Fernandez et al.   Mucosal Immunology

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

(2014) Nozomi Takahashi et al.   NATURE

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

(2014) Marius Dannappel et al.   NATURE

Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

(2014) B. Zhang et al.   SCIENCE

Innate lymphoid cells regulate intestinal epithelial cell glycosylation

(2014) Y. Goto et al.   SCIENCE

A20 controls intestinal homeostasis through cell-specific activities

(2014) Lars Vereecke et al.   Nature Communications

Thymic Stromal Lymphopoietin-Mediated Extramedullary Hematopoiesis Promotes Allergic Inflammation

(2013) Mark C. Siracusa et al.   IMMUNITY

Intestinal epithelial cells as mediators of the commensal-host immune crosstalk

(2013) Yoshiyuki Goto et al.   IMMUNOLOGY AND CELL BIOLOGY

Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

(2013) Stefanie Kirchberger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection

(2013) S. Ivanov et al.   JOURNAL OF VIROLOGY

IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites

(2013) A Bonnegarde-Bernard et al.   Mucosal Immunology

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

(2013) Hongbo Hu et al.   NATURE

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

(2013) Ben Roediger et al.   NATURE IMMUNOLOGY

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TSLP Elicits IL-33-Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation

(2013) B. S. Kim et al.   Science Translational Medicine

Innate Lymphoid Cells: Emerging Insights in Development, Lineage Relationships, and Function

(2012) Hergen Spits et al.   Annual Review of Immunology

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

(2012) Alan M. Hanash et al.   IMMUNITY

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells

(2012) Jenny Mjösberg et al.   IMMUNITY

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4

(2012) M. Iseki et al.   INTERNATIONAL IMMUNOLOGY

CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

(2012) C Manta et al.   Mucosal Immunology

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection

(2012) N R Klatt et al.   Mucosal Immunology

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

(2012) C J Kim et al.   Mucosal Immunology

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

(2012) G. F. Sonnenberg et al.   SCIENCE

Lymphotoxin Controls the IL-22 Protection Pathway in Gut Innate Lymphoid Cells during Mucosal Pathogen Challenge

(2011) Alexei V. Tumanov et al.   Cell Host & Microbe

Identity, regulation andin vivofunction of gut NKp46+RORγt+and NKp46+RORγt−lymphoid cells

(2011) Ana Reynders et al.   EMBO JOURNAL

Thymic Stromal Lymphopoetin-Induced Expression of the Endogenous Inhibitory Enzyme SLPI Mediates Recovery from Colonic Inflammation

(2011) Colin Reardon et al.   IMMUNITY

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

(2011) Katerina Vlantis et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease

(2011) Alessandra Geremia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

(2011) Monica Guma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

(2011) Patrick-Simon Welz et al.   NATURE

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

(2011) Mark C. Siracusa et al.   NATURE

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

(2011) Naruhisa Ota et al.   NATURE IMMUNOLOGY

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

(2011) E. A. Kiss et al.   SCIENCE

The intestinal epithelial barrier in the control of homeostasis and immunity

(2011) Maria Rescigno   TRENDS IN IMMUNOLOGY

Epithelial Barriers in Homeostasis and Disease

(2010) Amanda M. Marchiando et al.   Annual Review of Pathology-Mechanisms of Disease

Lymphotoxin Beta Receptor Signaling in Intestinal Epithelial Cells Orchestrates Innate Immune Responses against Mucosal Bacterial Infection

(2010) Yugang Wang et al.   IMMUNITY

Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes

(2010) Cedric Vonarbourg et al.   IMMUNITY

Interleukin-1β Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue

(2010) Tiffany Hughes et al.   IMMUNITY

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

(2010) Gregory F. Sonnenberg et al.   IMMUNITY

Novel Changes in NF-κB Activity during Progression and Regression Phases of Hyperplasia

(2010) Parthasarathy Chandrakesan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

(2010) Sofia Buonocore et al.   NATURE

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

(2010) Li-Chung Hsu et al.   NATURE IMMUNOLOGY

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

(2009) I D Iliev et al.   GUT

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

(2009) Betsy C. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The NF-κB-independent functions of IKK subunits in immunity and cancer

(2009) Alain Chariot   TRENDS IN CELL BIOLOGY

IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer

(2008) Bigang Liu et al.   CANCER CELL

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE

IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut

(2008) M Pasparakis   Mucosal Immunology

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Compensatory IKK  activation of classical NF- B signaling during IKK  inhibition identified by an RNA interference sensitization screen

(2008) L. T. Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing functions of IKK  during acute and chronic intestinal inflammation

(2008) L. Eckmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Citrobacter rodentium-induced NF-κB activation in hyperproliferating colonic epithelia: role of p65 (Ser536) phosphorylation

(2006) Yu Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY