Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

Both Radioresistant and Hemopoietic Cells Promote Innate and Adaptive Immune Responses to Flagellin

(2014) C. J. Sanders et al.   JOURNAL OF IMMUNOLOGY

Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation

(2014) M. Vijay-Kumar et al.   JOURNAL OF IMMUNOLOGY

Antibiotic Treatment Suppresses Rotavirus Infection and Enhances Specific Humoral Immunity

(2014) Robin Uchiyama et al.   JOURNAL OF INFECTIOUS DISEASES

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria

(2012) Rajatava Basu et al.   IMMUNITY

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges

(2012) F A Carvalho et al.   Mucosal Immunology

NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8+ T cells

(2012) Andreas Kupz et al.   NATURE IMMUNOLOGY

Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis

(2012) Jelena M Kezic et al.   ARTHRITIS RESEARCH & THERAPY

Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity

(2011) R. M. Jones et al.   GUT

The Reovirus  1s Protein Is a Determinant of Hematogenous but Not Neural Virus Dissemination in Mice

(2011) K. W. Boehme et al.   JOURNAL OF VIROLOGY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

(2010) Matam Vijay-Kumar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Post-entry Step in the Mammalian Orthoreovirus Replication Cycle Is a Determinant of Cell Tropism

(2010) Laura S. Ooms et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa

(2010) L. Van Maele et al.   JOURNAL OF IMMUNOLOGY

Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components

(2010) A H Frias et al.   Mucosal Immunology

Induction of adaptive immunity by flagellin does not require robust activation of innate immunity

(2009) Catherine J. Sanders et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rotaviruses: From Pathogenesis to Vaccination

(2009) Harry B. Greenberg et al.   GASTROENTEROLOGY

IRF3 Inhibition by Rotavirus NSP1 Is Host Cell and Virus Strain Dependent but Independent of NSP1 Proteasomal Degradation

(2009) A. Sen et al.   JOURNAL OF VIROLOGY

Flagellin: key target of mucosal innate immunity

(2009) M Vijay-Kumar et al.   Mucosal Immunology

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Qualitative and Quantitative Characteristics of Rotavirus-Specific CD8 T Cells Vary Depending on the Route of Infection

(2008) J. Q. Jiang et al.   JOURNAL OF VIROLOGY

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

(2008) L. G. Burdelya et al.   SCIENCE