A fresh look at zebrafish from the perspective of cancer research

Rapid reverse genetic screening using CRISPR in zebrafish

(2015) Arish N Shah et al.   NATURE METHODS

Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development

(2014) J. Wang et al.   CANCER RESEARCH

Zebrafish Model in Drug Safety Assessment

(2014) Jyotshna Kanungo et al.   CURRENT PHARMACEUTICAL DESIGN

An In Vivo Antilymphatic Screen in Zebrafish Identifies Novel Inhibitors of Mammalian Lymphangiogenesis and Lymphatic-Mediated Metastasis

(2014) J. W. Astin et al.   MOLECULAR CANCER THERAPEUTICS

Zebrafish as an emerging model for studying complex brain disorders

(2014) Allan V. Kalueff et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells

(2013) Y. Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluating human cancer cell metastasis in zebrafish

(2013) Yong Teng et al.   BMC CANCER

New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis

(2013) Miwa Kuroyanagi et al.   BMC GENOMICS

Anti-angiogenesis in cancer therapy: Hercules and hydra

(2013) S. Bellou et al.   CANCER LETTERS

Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis

(2013) N. Y. Storer et al.   DEVELOPMENT

A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening

(2013) M. M. J. Da Costa et al.   Disease Models & Mechanisms

Orthotopic transplantation of retinoblastoma cells into vitreous cavity of zebrafish for screening of anticancer drugs

(2013) Dong Jo et al.   Molecular Cancer

Developing zebrafish models of autism spectrum disorder (ASD)

(2013) Adam Michael Stewart et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

(2013) Sander G. Basten et al.   PLoS Genetics

Fish pharming: zebrafish antileukemia screening

(2012) W. K. Clements et al.   BLOOD

Zebrafish screen identifies novel compound with selective toxicity against leukemia

(2012) S. Ridges et al.   BLOOD

Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis

(2012) Shizhen Zhu et al.   CANCER CELL

A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis

(2012) Kirankumar Santhakumar et al.   CANCER RESEARCH

Zebrafish in the Study of Early Cardiac Development

(2012) Jiandong Liu et al.   CIRCULATION RESEARCH

A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors

(2012) Z. Li et al.   Disease Models & Mechanisms

TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

(2012) R. Espin et al.   Disease Models & Mechanisms

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

(2012) J. Shin et al.   Disease Models & Mechanisms

Think Small: Zebrafish as a Model System of Human Pathology

(2012) J. R. Goldsmith et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Hooked! Modeling human disease in zebrafish

(2012) Cristina Santoriello et al.   JOURNAL OF CLINICAL INVESTIGATION

Reverse Genetic Approaches in Zebrafish

(2012) Peng Huang et al.   Journal of Genetics and Genomics

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

(2012) Shuning He et al.   JOURNAL OF PATHOLOGY

An affective disorder in zebrafish with mutation of the glucocorticoid receptor

(2012) L Ziv et al.   MOLECULAR PSYCHIATRY

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis

(2011) Leda Mirbahai et al.   BMC GENOMICS

Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells

(2011) Grace GL Yue et al.   BRITISH JOURNAL OF PHARMACOLOGY

Zebrafish as a model to study cardiac development and human cardiac disease

(2011) J. Bakkers   CARDIOVASCULAR RESEARCH

An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening

(2011) A. T. Nguyen et al.   Disease Models & Mechanisms

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

(2011) S. W. Leacock et al.   Disease Models & Mechanisms

Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma

(2011) S. Choorapoikayil et al.   Disease Models & Mechanisms

Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish

(2011) Ayca Cinaroglu et al.   HEPATOLOGY

Zebrafish embryo, a tool to study tumor angiogenesis

(2011) Chiara Tobia et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Hair Cell Toxicity in Anti-cancer Drugs: Evaluating an Anti-cancer Drug Library for Independent and Synergistic Toxic Effects on Hair Cells Using the Zebrafish Lateral Line

(2011) Yoshinobu Hirose et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile

(2011) Ardian Latifi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia

(2011) Alejandro Gutierrez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish

(2011) Zhen Li et al.   JOURNAL OF HEPATOLOGY

DHODH modulates transcriptional elongation in the neural crest and melanoma

(2011) Richard Mark White et al.   NATURE

High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope

(2011) Jessica S Blackburn et al.   Nature Protocols

Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish

(2011) S Camus et al.   ONCOGENE

Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay

(2011) Karni S. Moshal et al.   Cancers

The in vivo performance of plasmonic nanobubbles as cell theranostic agents in zebrafish hosting prostate cancer xenografts

(2010) Daniel S. Wagner et al.   BIOMATERIALS

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia

(2010) A. C. H. Smith et al.   BLOOD

Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer

(2010) Chunyang Wang et al.   EUROPEAN UROLOGY

In vivo analysis of gut function and disease changes in a zebrafish larvae model of inflammatory bowel disease

(2010) Angeleen Fleming et al.   INFLAMMATORY BOWEL DISEASES

Generation of clonal zebrafish lines and transplantable hepatic tumors

(2010) Igor Mizgirev et al.   Nature Protocols

brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis

(2010) H. R. Shive et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LIMK1 and LIMK2 Are Important for Metastatic Behavior and Tumor Cell-Induced Angiogenesis of Pancreatic Cancer Cells

(2010) Danielle H. Vlecken et al.   Zebrafish

Identification of a Heritable Model of Testicular Germ Cell Tumor in the Zebrafish

(2010) Joanie C. Neumann et al.   Zebrafish

Zebrafish Models of p53 Functions

(2010) N. Y. Storer et al.   Cold Spring Harbor Perspectives in Biology

Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model

(2009) Ines J Marques et al.   BMC CANCER

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer

(2009) Frank Ulrich Weiss et al.   GASTROENTEROLOGY

Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish

(2009) Bensheng Ju et al.   Molecular Cancer

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model

(2009) S. L. C. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic NRAS Cooperates with p53 Loss to Generate Melanoma in Zebrafish

(2009) Michael Dovey et al.   Zebrafish

Lgl2 Executes Its Function as a Tumor Suppressor by Regulating ErbB Signaling in the Zebrafish Epidermis

(2009) Sven Reischauer et al.   PLoS Genetics

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Oncogenic KRAS Induces Progenitor Cell Expansion and Malignant Transformation in Zebrafish Exocrine Pancreas

(2008) Seung Woo Park et al.   GASTROENTEROLOGY

Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation

(2008) Michael J. Passeri et al.   HEPATOLOGY

Zebrafish as a Cancer Model

(2008) H. Feitsma et al.   MOLECULAR CANCER RESEARCH

Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio

(2007) Ravikumar Deepa Rekha et al.   TOXICOLOGY