Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy

A method to measure cardiac autophagic flux in vivo

(2014) Eri Iwai-Kanai et al.   Autophagy

Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses

(2014) Satoshi Okumura et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiovascular autophagy

(2013) Sergio Lavandero et al.   Autophagy

Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle

(2013) Olivier Roger Joassard et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Staphylococcus aureus promotes autophagy by decreasing intracellular cAMP levels

(2012) María Belén Mestre et al.   Autophagy

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Mechanisms of Autophagosome Biogenesis

(2012) David C. Rubinsztein et al.   CURRENT BIOLOGY

Dissociation of Bcl-2-Beclin1 Complex by Activated AMPK Enhances Cardiac Autophagy and Protects Against Cardiomyocyte Apoptosis in Diabetes

(2012) C. He et al.   DIABETES

Autophagy: an affair of the heart

(2012) Roberta A. Gottlieb et al.   HEART FAILURE REVIEWS

Identification of a Tetrahydroquinoline Analog as a Pharmacological Inhibitor of the cAMP-binding Protein Epac

(2012) Delphine Courilleau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rap-linked cAMP signaling Epac proteins: Compartmentation, functioning and disease implications

(2011) Magali Breckler et al.   CELLULAR SIGNALLING

Epac enhances excitation–transcription coupling in cardiac myocytes

(2011) Laetitia Pereira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

(2010) C Muller et al.   CELL DEATH AND DIFFERENTIATION

Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway

(2010) Mélanie Métrich et al.   CELLULAR SIGNALLING

Role of Inositol Trisphosphate Receptors in Autophagy in DT40 Cells

(2010) M. Tariq Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Adrenergic stimulation and myocardial function in the failing heart

(2009) Ali El-Armouche et al.   HEART FAILURE REVIEWS

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy

(2008) Paul Tannous et al.   CIRCULATION

Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy

(2008) Mélanie Métrich et al.   CIRCULATION RESEARCH

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

(2008) Andrea Williams et al.   Nature Chemical Biology

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology