Autophagy: an affair of the heart

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Mitofusins 1 and 2 Are Essential for Postnatal Metabolic Remodeling in Heart

(2012) Kyriakos N. Papanicolaou et al.   CIRCULATION RESEARCH

Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes

(2012) Ting Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress

(2012) Gladys A. Ngoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic homeostasis of the heart: Figure 1.

(2012) Robert S. Balaban   JOURNAL OF GENERAL PHYSIOLOGY

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes

(2011) Youngil Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy limits acute myocardial infarction induced by permanent coronary artery occlusion

(2011) Hiromitsu Kanamori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of autophagy emerging in postinfarction cardiac remodelling

(2011) Hiromitsu Kanamori et al.   CARDIOVASCULAR RESEARCH

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

(2011) Yun Chen et al.   CIRCULATION RESEARCH

CARDIOPROTECTIVE EFFECTS OF CHLORAMPHENICOL ARE MEDIATED BY AUTOPHAGY

(2011) Zoltan Giricz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

(2011) Chengqun Huang et al.   PLoS One

SLO-2 Is Cytoprotective and Contributes to Mitochondrial Potassium Transport

(2011) Andrew P. Wojtovich et al.   PLoS One

Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters

(2010) Sebastian J. Buss et al.   Autophagy

Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder—murine Pompe disease

(2010) Nina Raben et al.   Autophagy

Autophagosome maturation is impaired in Fabry disease

(2010) Marc Chévrier et al.   Autophagy

Inhibition of autophagy in the heart induces age-related cardiomyopathy

(2010) Manabu Taneike et al.   Autophagy

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning

(2010) D. J. Hausenloy et al.   CARDIOVASCULAR RESEARCH

Profound Cardioprotection With Chloramphenicol Succinate in the Swine Model of Myocardial Ischemia-Reperfusion Injury

(2010) J. A. Sala-Mercado et al.   CIRCULATION

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Is Autophagy in Response to Ischemia and Reperfusion Protective or Detrimental for the Heart?

(2010) Sebastiano Sciarretta et al.   PEDIATRIC CARDIOLOGY

Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection

(2010) Chengqun Huang et al.   Journal of Cardiovascular Translational Research

Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole

(2009) Chengqun Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Markers of Autophagy Are Downregulated in Failing Human Heart After Mechanical Unloading

(2009) C. Kassiotis et al.   CIRCULATION

Effects of Statin Therapy According to Plasma High-Sensitivity C-Reactive Protein Concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

(2009) John J.V. McMurray et al.   CIRCULATION

Beneficial Effects of Mammalian Target of Rapamycin Inhibition on Left Ventricular Remodeling After Myocardial Infarction

(2009) Sebastian J. Buss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Heart Disease and Stroke Statistics—2009 Update

(2008) et al.   CIRCULATION

Crosstalk Between Autophagy and Apoptosis in Heart Disease

(2008) Kazuhiko Nishida et al.   CIRCULATION RESEARCH

Autophagy in Load-Induced Heart Disease

(2008) Beverly A. Rothermel et al.   CIRCULATION RESEARCH

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

A PGC-1α-O-GlcNAc Transferase Complex Regulates FoxO Transcription Factor Activity in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Experimental and Clinical Basis for the Use of Statins in Patients With Ischemic and Nonischemic Cardiomyopathy

(2008) Kumudha Ramasubbu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Autophagy is an adaptive response in desmin-related cardiomyopathy

(2008) P. Tannous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of enzyme replacement therapy on the cardiomyopathy of Anderson Fabry disease: a randomised, double-blind, placebo-controlled clinical trial of agalsidase alfa

(2007) D A Hughes et al.   HEART

Ischemic preconditioning modulates mitochondrial respiration, irrespective of the employed signal transduction pathway

(2007) David A. Liem et al.   Translational Research