Cardiac anaplerosis in health and disease: food for thought

Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization

(2010) David N. Brindley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice

(2010) Outi M. Hyyti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate

(2010) Karlos X. Moreno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of insulin secretion: role of mitochondrial signalling

(2010) S. Jitrapakdee et al.   DIABETOLOGIA

Modification of myocardial substrate utilisation: a new therapeutic paradigm in cardiovascular disease

(2010) R. M. Beadle et al.   HEART

Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice

(2010) Preeti Ahuja et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dipropionylcysteine Ethyl Ester Compensates for Loss of Citric Acid Cycle Intermediates During Post Ischemia Reperfusion in the Pig Heart

(2009) Takhar Kasumov et al.   CARDIOVASCULAR DRUGS AND THERAPY

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Substrate–Enzyme Competition Attenuates Upregulated Anaplerotic Flux Through Malic Enzyme in Hypertrophied Rat Heart and Restores Triacylglyceride Content

(2009) Kayla M. Pound et al.   CIRCULATION RESEARCH

Alterations in mitochondrial function as a harbinger of cardiomyopathy: Lessons from the dystrophic heart

(2009) Yan Burelle et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiomyopathies in Propionic Aciduria are Reversible After Liver Transplantation

(2009) Stéphane Romano et al.   JOURNAL OF PEDIATRICS

Micronutrient Deficiencies

(2009) Victor Soukoulis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Adrenergic-Fatty Acid Load in Heart Failure

(2009) Lionel H. Opie et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Multiple OXPHOS Deficiency in the Liver, Kidney, Heart, and Skeletal Muscle of Patients With Methylmalonic Aciduria and Propionic Aciduria

(2009) Yves de Keyzer et al.   PEDIATRIC RESEARCH

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Alterations in carbohydrate metabolism and its regulation in PPARα null mouse hearts

(2008) Roselle Gélinas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion

(2008) Aaron K. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Succination of Proteins by Fumarate

(2008) Matthew Blatnik et al.   Annals of the New York Academy of Sciences

Metabolic (In)Flexibility of the Diabetic Heart

(2008) Terje S. Larsen et al.   CARDIOVASCULAR DRUGS AND THERAPY

Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease

(2008) François Labarthe et al.   CARDIOVASCULAR DRUGS AND THERAPY

Role of diet and fuel overabundance in the development and progression of heart failure

(2008) D. J. Chess et al.   CARDIOVASCULAR RESEARCH

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

(2008) Mariana G. Rosca et al.   CARDIOVASCULAR RESEARCH

Energy metabolism in heart failure and remodelling

(2008) J. S. Ingwall   CARDIOVASCULAR RESEARCH

Nonischemic heart failure in diabetes mellitus

(2008) Ashrith Guha et al.   CURRENT OPINION IN CARDIOLOGY

Mitochondrial fatty acid oxidation defects—remaining challenges

(2008) Niels Gregersen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulation

(2008) Ramzi J. Khairallah et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tackling heart failure in the twenty-first century

(2008) James O. Mudd et al.   NATURE

Carnitine palmitoyltransferase II deficiency: Successful anaplerotic diet therapy

(2008) C. R. Roe et al.   NEUROLOGY

Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency

(2008) M. Khairallah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

(2008) D. R. Wise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA