Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Effect of Fibrates on Lipid Profiles and Cardiovascular Outcomes: A Systematic Review

(2009) Samuel Abourbih et al.   AMERICAN JOURNAL OF MEDICINE

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5

(2009) Martina Schweiger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

(2009) Kazuharu Takeuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats

(2009) Arend Bonen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Diabetes and apoptosis: lipotoxicity

(2009) Christine M. Kusminski et al.   APOPTOSIS

Sarcolemmal fatty acid uptake vs. mitochondrial β-oxidation as target to regress cardiac insulin resistanceThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Joost J.F.P. Luiken   Applied Physiology Nutrition and Metabolism

Triglyceride lipases alter fuel metabolism and mitochondrial gene expressionThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Matthew J. Watt   Applied Physiology Nutrition and Metabolism

Suppression of cardiac phosphatidate phosphohydrolase 1 activity and lipin mRNA expression in Zucker diabetic fatty rats and humans with type 2 diabetes mellitus

(2009) Christof Burgdorf et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

As a Matter of Fat

(2009) Rita T. Brookheart et al.   Cell Metabolism

Paradoxical Coupling of Triglyceride Synthesis and Fatty Acid Oxidation in Skeletal Muscle Overexpressing DGAT1

(2009) L. Liu et al.   DIABETES

DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity

(2009) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac Expression of Microsomal Triglyceride Transfer Protein Is Increased in Obesity and Serves to Attenuate Cardiac Triglyceride Accumulation

(2009) Emil D. Bartels et al.   PLoS One

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

(2008) Masami Ueno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Thiazolidinediones in Type 2 Diabetes: A Cardiology Perspective

(2008) Ujjaini Khanderia et al.   ANNALS OF PHARMACOTHERAPY

Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition

(2008) Tal M. Lewin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Reassessing the Cardiovascular Risks and Benefits of Thiazolidinediones

(2008) Andrew Zinn et al.   CLINICAL CARDIOLOGY

Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: A role for combination fibrate therapy

(2008) Sergio Fazio   CLINICAL THERAPEUTICS

Muscle-Specific IRS-1 Ser->Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

(2008) K. Morino et al.   DIABETES

The Double Role of Epicardial Adipose Tissue as Pro- and Anti-inflammatory Organ

(2008) G. Iacobellis et al.   HORMONE AND METABOLIC RESEARCH

Oleate Reverses Palmitate-induced Insulin Resistance and Inflammation in Skeletal Muscle Cells

(2008) Teresa Coll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis

(2008) Peixiang Zhang et al.   JOURNAL OF LIPID RESEARCH

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

(2008) Rudolf Zechner et al.   JOURNAL OF LIPID RESEARCH

Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically

(2008) Boripont Manmontri et al.   JOURNAL OF LIPID RESEARCH

Thematic Review Series: Glycerolipids.Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism

(2008) Karen Reue et al.   JOURNAL OF LIPID RESEARCH

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

Adipose Triglyceride Lipase Regulation of Skeletal Muscle Lipid Metabolism and Insulin Responsiveness

(2008) Matthew J. Watt et al.   MOLECULAR ENDOCRINOLOGY

Triglyceride Deposit Cardiomyovasculopathy

(2008) Ken-ichi Hirano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diacylglycerol acyltransferases: Potential roles as pharmacological targets

(2008) Victor A. Zammit et al.   PHARMACOLOGY & THERAPEUTICS

Cardiac Remodeling in Obesity

(2008) E. Dale Abel et al.   PHYSIOLOGICAL REVIEWS

Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice

(2007) Ellen Aasum et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lipid accumulation in non-adipose tissue and lipotoxicity

(2007) N.A. van Herpen et al.   PHYSIOLOGY & BEHAVIOR