Atorvastatin prevents ATP-driven invasiveness via P2X7 and EHBP1 signaling in PTEN-expressing prostate cancer cells

Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells

(2013) Ingrid Espinoza et al.   CANCER LETTERS

Drosophila EHBP1 regulates Scabrous secretion during Notch-mediated lateral inhibition

(2013) N. Giagtzoglou et al.   JOURNAL OF CELL SCIENCE

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

(2013) Liuqing Yang et al.   NATURE

Genetic Susceptibility Loci, Pesticide Exposure and Prostate Cancer Risk

(2013) Stella Koutros et al.   PLoS One

Statin Use in Relation to Prostate Cancer Outcomes in a Population-based Patient Cohort Study

(2013) Milan S. Geybels et al.   PROSTATE

The emerging multiple roles of nuclear Akt

(2012) Alberto M. Martelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The differential effects of statins on the metastatic behaviour of prostate cancer

(2012) M Brown et al.   BRITISH JOURNAL OF CANCER

Expression of P2X7 Receptor Increases In Vivo Tumor Growth

(2012) E. Adinolfi et al.   CANCER RESEARCH

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

(2012) William A. Freed-Pastor et al.   CELL

TNF-α triggers rapid membrane insertion of Ca2+ permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury

(2012) Hong Z. Yin et al.   EXPERIMENTAL NEUROLOGY

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Statin Use and Risk of Prostate Cancer: A Meta-Analysis of Observational Studies

(2012) Dipika Bansal et al.   PLoS One

Rho GEFs and Cancer: Linking Gene Expression and Metastatic Dissemination

(2012) L. Barrio-Real et al.   Science Signaling

Silencing p110β prevents rapid depletion of nuclear pAkt

(2011) Zhi-wei Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comparative effects of high and low-dose simvastatin on prostate epithelial cells: The role of LDL

(2011) Teemu J. Murtola et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Epigenetic Regulation of Phosphatidylinositol 3,4,5-Triphosphate-dependent Rac Exchanger 1 Gene Expression in Prostate Cancer Cells

(2011) Chuu-Yun A. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of P-Rex1 as a Novel Rac1-Guanine Nucleotide Exchange Factor (GEF) That Promotes Actin Remodeling and GLUT4 Protein Trafficking in Adipocytes

(2011) Demis Balamatsias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statins and Prostate Cancer Diagnosis and Grade in a Veterans Population

(2011) W. R. Farwell et al.   JNCI-Journal of the National Cancer Institute

P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness

(2011) B Jelassi et al.   ONCOGENE

Extracellular ATP enhances in vitro invasion of prostate cancer cells by activating Rho GTPase and upregulating MMPs expression

(2010) Yang Zhang et al.   CANCER LETTERS

Purinergic Receptor-mediated Rapid Depletion of Nuclear Phosphorylated Akt Depends on Pleckstrin Homology Domain Leucine-rich Repeat Phosphatase, Calcineurin, Protein Phosphatase 2A, and PTEN Phosphatases

(2010) Oras Mistafa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

(2010) M. P. Lees et al.   JOURNAL OF IMMUNOLOGY

Anticancer Efficacy of Simvastatin on Prostate Cancer Cells and Tumor Xenografts Is Associated with Inhibition of Akt and Reduced Prostate-Specific Antigen Expression

(2010) S. T. Kochuparambil et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

EHBP-1 Functions with RAB-10 during Endocytic Recycling in Caenorhabditis elegans

(2010) Anbing Shi et al.   MOLECULAR BIOLOGY OF THE CELL

A constitutively activated form of the p110  isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice

(2010) S. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells

(2009) Oras Mistafa et al.   BIOCHEMICAL PHARMACOLOGY

Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice

(2009) R.A. Mans et al.   NEUROSCIENCE

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

Activation of the PI3K Pathway in Cancer Through Inhibition of PTEN by Exchange Factor P-REX2a

(2009) B. Fine et al.   SCIENCE

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

(2008) Julius Gudmundsson et al.   NATURE GENETICS

Statins and ATP regulate nuclear pAkt via the P2X7 purinergic receptor in epithelial cells

(2007) Oras Mistafa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS