Purinergic Receptor-mediated Rapid Depletion of Nuclear Phosphorylated Akt Depends on Pleckstrin Homology Domain Leucine-rich Repeat Phosphatase, Calcineurin, Protein Phosphatase 2A, and PTEN Phosphatases

C/EBP  targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression

(2010) S. A. Pawar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells

(2009) Oras Mistafa et al.   BIOCHEMICAL PHARMACOLOGY

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

p85 Associates with Unphosphorylated PTEN and the PTEN-Associated Complex

(2009) R. Rabinovsky et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

(2009) M. Marques et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4

(2008) Younghee Ahn et al.   BIOCHEMICAL JOURNAL

Calcineurin mediates AKT dephosphorylation in the ischemic rat retina

(2008) Chang Hwan Park et al.   BRAIN RESEARCH

Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers

(2008) Q Zhu et al.   ONCOGENE

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis

(2008) J Liu et al.   ONCOGENE

The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

(2008) F. Fouladkou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rationale for statins in the chemoprevention of prostate cancer

(2008) Robert J. Hamilton et al.   Current Urology Reports

Statins and ATP regulate nuclear pAkt via the P2X7 purinergic receptor in epithelial cells

(2007) Oras Mistafa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS