Identification of P-Rex1 as a Novel Rac1-Guanine Nucleotide Exchange Factor (GEF) That Promotes Actin Remodeling and GLUT4 Protein Trafficking in Adipocytes

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle

(2011) Tim T. Chiu et al.   CELLULAR SIGNALLING

Mapping Insulin/GLUT4 Circuitry

(2011) Alexander F. Rowland et al.   TRAFFIC

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

(2010) Shuji Ueda et al.   FASEB JOURNAL

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans

(2010) Joshua P. Lewis et al.   GENOMICS

Desialylation of insulin receptors and IGF-1 receptors by neuraminidase-1 controls the net proliferative response of L6 myoblasts to insulin

(2010) M. Arabkhari et al.   GLYCOBIOLOGY

P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer

(2010) J C Montero et al.   ONCOGENE

Changes in the signalling status of the small GTP-binding proteins Rac and Rho do not influence insulin-stimulated hexose transport

(2009) J. Dorrestijn et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Identification of a Distal GLUT4 Trafficking Event Controlled by Actin Polymerization

(2009) Jamie A. Lopez et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidylinositol 3,4,5-Triphosphate-Dependent Rac Exchanger 1 (P-Rex-1), a Guanine Nucleotide Exchange Factor for Rac, Mediates Angiogenic Responses to Stromal Cell-Derived Factor-1/Chemokine Stromal Cell Derived Factor-1 (SDF-1/CXCL-12) Linked to Rac Activation, Endothelial Cell Migration, and in Vitro Angiogenesis

(2009) J. Carretero-Ortega et al.   MOLECULAR PHARMACOLOGY

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1

(2008) J.L. Bento et al.   GENOMICS

P-Rex1 - a multidomain protein that regulates neurite differentiation

(2008) J. E. Waters et al.   JOURNAL OF CELL SCIENCE