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Title
Metformin targets c-MYC oncogene to prevent prostate cancer
Authors
Keywords
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Journal
CARCINOGENESIS
Volume 34, Issue 12, Pages 2823-2832
Publisher
Oxford University Press (OUP)
Online
2013-10-16
DOI
10.1093/carcin/bgt307
References
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Related references
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- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
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- (2012) Giovanni Blandino et al. Nature Communications
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- (2011) Li Zhao et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- A prospective, randomized pilot study evaluating the effects of metformin and lifestyle intervention on patients with prostate cancer receiving androgen deprivation therapy
- (2011) Jenny P. Nobes et al. BJU INTERNATIONAL
- Metformin and the Incidence of Prostate Cancer in Patients with Type 2 Diabetes
- (2011) L. Azoulay et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland
- (2011) X. Wang et al. CANCER RESEARCH
- The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells
- (2011) Alejandro Vazquez-Martin et al. CELL CYCLE
- New Hormonal Therapies for Castration-Resistant Prostate Cancer
- (2011) Elahe A. Mostaghel et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors
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- The combination of metformin and 2 deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells
- (2010) Issam Ben Sahra et al. Autophagy
- Cancer Statistics, 2010
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- Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells
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- MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells
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- Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
- (2010) E. Kickstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
- (2009) C. V. Dang et al. CLINICAL CANCER RESEARCH
- The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
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- Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
- (2008) Bora Gurel et al. MODERN PATHOLOGY
- The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
- (2008) I Ben Sahra et al. ONCOGENE
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