Metformin, an Antidiabetic Agent Reduces Growth of Cutaneous Squamous Cell Carcinoma by Targeting mTOR Signaling Pathway†

The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In Vivo

(2012) K. Kato et al.   MOLECULAR CANCER THERAPEUTICS

Nitric Oxide Donor Exisulind Is an Effective Inhibitor of Murine Photocarcinogenesis†

(2012) Tripti Singh et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Cancer Prevention With a Diabetes Pill?

(2012) G. Taubes   SCIENCE

Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

(2011) Charbel Darido et al.   CANCER CELL

Rapamycin Is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate

(2011) L. Allyson Checkley et al.   Cancer Prevention Research

Rapamycin and mTORC1 Inhibition in the Mouse: Skin Cancer Prevention

(2011) Mohammad Athar et al.   Cancer Prevention Research

A Phase I Pharmacokinetic and Pharmacodynamic Study of Dalotuzumab (MK-0646), an Anti-Insulin-like Growth Factor-1 Receptor Monoclonal Antibody, in Patients with Advanced Solid Tumors

(2011) F. Atzori et al.   CLINICAL CANCER RESEARCH

Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models

(2011) J.-H. Cheong et al.   MOLECULAR CANCER THERAPEUTICS

PIK3CA Mutations in Patients with Advanced Cancers Treated with PI3K/AKT/mTOR Axis Inhibitors

(2011) F. Janku et al.   MOLECULAR CANCER THERAPEUTICS

Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153

(2011) N. WU et al.   NEOPLASMA

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

(2011) T Tomic et al.   Cell Death & Disease

Metformin as an antitumor agent in cancer prevention and treatment

(2011) Donghui LI   Journal of Diabetes

Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis

(2010) R. M. Memmott et al.   Cancer Prevention Research

Metformin and Other Biguanides in Oncology: Advancing the Research Agenda

(2010) M. Pollak   Cancer Prevention Research

Crosstalk between Insulin/Insulin-like Growth Factor-1 Receptors and G Protein-Coupled Receptor Signaling Systems: A Novel Target for the Antidiabetic Drug Metformin in Pancreatic Cancer

(2010) E. Rozengurt et al.   CLINICAL CANCER RESEARCH

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

(2010) I. Ben Sahra et al.   MOLECULAR CANCER THERAPEUTICS

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of the mammalian target of rapamycin signalling pathway in epidermal tumours and its correlation with cyclin-dependent kinase 2

(2009) S-J. Chen et al.   BRITISH JOURNAL OF DERMATOLOGY

Akt-dependent and -independent mechanisms of mTOR regulation in cancer

(2009) Regan M. Memmott et al.   CELLULAR SIGNALLING

New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes

(2009) G. Libby et al.   DIABETES CARE

The IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer

(2009) D A Lewis et al.   ONCOGENE

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

(2008) S. Gurumurthy et al.   CANCER RESEARCH

Inhibition of Mammalian Target of Rapamycin by Rapamycin Causes the Regression of Carcinogen-Induced Skin Tumor Lesions

(2008) P. Amornphimoltham et al.   CLINICAL CANCER RESEARCH

Insulin, the Insulin-Like Growth Factor Axis, and Mortality in Patients With Nonmetastatic Colorectal Cancer

(2008) Brian M. Wolpin et al.   JOURNAL OF CLINICAL ONCOLOGY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

LKB1; linking cell structure and tumor suppression

(2008) A F Hezel et al.   ONCOGENE

Cyclooxygenase-2 Inhibitor Nimesulide Blocks Ultraviolet B-induced Photocarcinogenesis in SKH-1 Hairless Mice

(2008) Xiuwei Tang et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Metformin induces apoptosis of pancreatic cancer cells

(2008) Luo-Wei Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY