The essential role of PIM kinases in sarcoma growth and bone invasion

Roles of Pim-3, a novel survival kinase, in tumorigenesis

(2011) Naofumi Mukaida et al.   CANCER SCIENCE

The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells

(2011) D. Xu et al.   CARCINOGENESIS

Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition

(2010) Carmen Blanco-Aparicio et al.   CANCER LETTERS

Why target PIM1 for cancer diagnosis and treatment?

(2010) Nancy S Magnuson et al.   Future Oncology

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

(2010) L. Brault et al.   HAEMATOLOGICA

Regulation of GSK3 isoforms by phosphatases PP1 and PP2A

(2010) Félix Hernández et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

(2010) Niina M Santio et al.   Molecular Cancer

Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver

(2010) Y Wu et al.   ONCOGENE

Hypoxia-Mediated Up-Regulation of Pim-1 Contributes to Solid Tumor Formation

(2009) Jian Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

The PKB/AKT Pathway in Cancer

(2009) Amancio Carnero   CURRENT PHARMACEUTICAL DESIGN

PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications

(2009) Min En Nga et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Pim-3 is expressed in endothelial cells and promotes vascular tube formation

(2009) Peng Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration

(2009) Rebekka Grundler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes

(2009) S. M. Mumenthaler et al.   MOLECULAR CANCER THERAPEUTICS

Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells

(2009) Z. Beharry et al.   MOLECULAR CANCER THERAPEUTICS

Pim-1 plays a pivotal role in hypoxia-induced chemoresistance

(2009) J Chen et al.   ONCOGENE

Pim Kinases Promote Cell Cycle Progression by Phosphorylating and Down-regulating p27Kip1 at the Transcriptional and Posttranscriptional Levels

(2008) D. Morishita et al.   CANCER RESEARCH

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Potential roles for the PIM1 kinase in human cancer – A molecular and therapeutic appraisal

(2008) Nilesh Shah et al.   EUROPEAN JOURNAL OF CANCER