Roles of Pim-3, a novel survival kinase, in tumorigenesis

Pim3 negatively regulates glucose-stimulated insulin secretion

(2011) Gregory Vlacich et al.   Islets

The Akt/PKB Family of Protein Kinases: A Review of Small Molecule Inhibitors and Progress Towards Target Validation: A 2009 Update

(2010) Craig Lindsley   CURRENT TOPICS IN MEDICINAL CHEMISTRY

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

(2010) L. Brault et al.   HAEMATOLOGICA

Cell-permeable Carboxyl-terminal p27Kip1Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 Kinase

(2010) Daisuke Morishita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver

(2010) Y Wu et al.   ONCOGENE

The Pim protein kinases regulate energy metabolism and cell growth

(2010) Z. Beharry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma

(2009) Y.-W. Lin et al.   BLOOD

Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells

(2009) L. S. Chen et al.   BLOOD

Pim-3 protects against hepatic failure in D-galactosamine (D-GalN)-sensitized rats

(2009) L.-M. Liu et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Pim-3 protects against cardiomyocyte apoptosis in anoxia/reoxygenation injury via p38-mediated signal pathway

(2009) Dan Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pim-3 is expressed in endothelial cells and promotes vascular tube formation

(2009) Peng Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Synthesis, Kinase Inhibitory Potencies, and in Vitro Antiproliferative Evaluation of New Pim Kinase Inhibitors

(2009) Rufine Akué-Gédu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor

(2009) Alex N. Bullock et al.   PLoS One

Pim Kinases Promote Cell Cycle Progression by Phosphorylating and Down-regulating p27Kip1 at the Transcriptional and Posttranscriptional Levels

(2008) D. Morishita et al.   CANCER RESEARCH

Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells

(2008) Ying-Yi Li et al.   CANCER SCIENCE

Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases

(2008) Zuping Xia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pim kinase-dependent inhibition of c-Myc degradation

(2008) Y Zhang et al.   ONCOGENE