Article
Food Science & Technology
Chatsachee Chatpapamon, Dudsadee Uttapap, Yuree Wandee, Chureerat Puttanlek, Vilai Rungsardthong
Summary: The study found that the effects of glycerol on different types of starch during heat-moisture treatment varied, with B-type potato and canna starches being more susceptible compared to A-type rice and cassava starches. The type of plasticizer as well as the environment surrounding the crystalline region also play a role in altering the starch during HMT.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Applied
Han Guo, Keiichiro Shiraga, Naoshi Kondo, Siyao Chen, Yoshihisa Yamashige, Yuichi Ogawa
Summary: The potential of Fourier-transform terahertz (FT-THz) spectroscopy to monitor crystalline structure changes in rice starch after heat-moisture treatment (HMT) was investigated. Crystallinity was measured by X-ray diffraction (XRD) spectra and found to be correlated with THz spectra. A-type and Vh-type crystallinity in rice starch, based on the A-type crystal structure and Vh-type crystalline structure of amylose-lipid complex (ALC), were quantified using THz peaks, with the intensity at 9.0 THz highly correlated with both A-type and Vh-type crystallinity and three other peaks at 10.5 THz, 12.2 THz, and 13.1 THz sensitive to Vh-type crystalline structure.
Article
Food Science & Technology
Chunsen Wu, Guiying Ji, Fan Gao, Jian-Ya Qian, Liang Zhang, Qian Li, Chen Zhang
Summary: Heat-moisture treatment of small granule sand rice starch at different moisture contents resulted in structural changes and improved properties, such as greater thermal stability, lower viscosity, and enhanced resistance to digestion. Treatment at 20% moisture content yielded the highest levels of SDS and RS.
FOOD SCIENCE & NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Xiaoyao Ji, Liyuan Rong, Qiang Yu, Yi Chen, Jinwang Li, Jianhua Xie
Summary: The effects of gallic acid and heat moisture treatment on the gel properties and microstructure of yam starch/chitosan composite gels were investigated. It was found that gallic acid and heat moisture treatment could effectively alter the gel properties of the composite gels, making them more suitable for practical application in the food industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Guiyuan Xiang, Jiangtao Li, Qinlu Lin, Yili Zhang, Yuqin Ding, Xiaofeng Guo, Qianru Pan, Qiongxiang Liu, Xiangjin Fu, Ying Yang, Wenfang Han, Yong Fang
Summary: This study examined the impact of removing proteins, lipids, and starch on the structure, physicochemical properties, and digestion properties of rice flour processed with heat moisture treatment (HMT). The results revealed that HMT caused the rice flour to adhere and agglomerate, leading to the formation of complexes, particularly starch-lipid complexes. Removing lipids had minimal effects on the crystallinity, gelatinization temperature, and viscosity properties of the HMT treated rice flour. However, removing proteins significantly increased the crystallinity, peak viscosity, final viscosity, breakdown, and starch digestibility.
Article
Biochemistry & Molecular Biology
Chang-Seon Lee, Hyun-Jung Chung
Summary: The objective of this study was to increase the resistant starch (RS) content of high amylose rice starch through heat-moisture treatment (HMT) for industrial application. The optimized HMT condition for achieving the highest RS content was determined to be a temperature of 100 degrees C, moisture content of 24.2%, and a time of 11.5 h. HMT increased the RS content from 32.1% to 46.4%.
Article
Biochemistry & Molecular Biology
Xiaoxue Lu, Jinling Zhan, Rongrong Ma, Yaoqi Tian
Summary: Rice starch-protein hydrolysate complexes with high resistant starch content were prepared by heat-moisture treatment and annealing. The effects of different hydrothermal treatments on the structure and thermal stability of the complexes and their relationship with starch digestibility were discussed. The results showed that annealing treatment resulted in higher resistant starch content and improved stability and interaction of the complexes. The hydrothermal treatment also made the scatterers denser and the surface smoother, hindering starch digestion to some extent.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Polymer Science
Edy Subroto, Mahani, Rossi Indiarto, Vira Putri Yarlina, Afifah Nurul Izzati
Summary: This review discusses the hydrothermal modifications of starch and flour and their effects on five parameters. In general, physical modification can improve functional properties, increase crystallinity, and gelatinization temperature, but sometimes may have the opposite effect.
Article
Biochemistry & Molecular Biology
Jiajun Wang, Yuxuan Ye, Ziqi Chai, Huiyan Liu, Xiaobo Wei, Xingqian Ye, Jinhu Tian, Haitian Fang
Summary: Heat-moisture treatment (HMT) and annealing (ANN) were applied to modify the physicochemical properties and in vitro digestion of proso millet starch. Results showed that both processes did not change the typical A-type crystallinity, but caused cracks and dents on the granule surface. The gelatinization temperature increased while peak viscosity value, relative crystallinity, and gelatinization enthalpy decreased significantly. Moreover, a remarkable increase in the content of slowly digestible starch (SDS) and resistant starch (RS) was observed after HMT and ANN modification, suggesting the potential application in producing healthier starch food with lower digestion.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Malgorzata Piecyk, Katarzyna Domian
Summary: In this study, the starch of two field bean cultivars was modified using HMT to investigate its physicochemical properties and digestibility. The HMT treatment led to changes in starch properties such as swelling power, amylose leaching, and gelatinization temperature, as well as altered digestibility. The modifications showed variation based on moisture content and temperature levels, ultimately affecting the content of resistant starch.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Zhiyuan Li, Dongshu Guo, Xiao Li, Zhaocheng Tang, Xitie Ling, Tiantian Zhou, Baolong Zhang
Summary: A novel rice germplasm sbeIIb/Lgc1 has been developed through CRISPR/Cas9-mediated targeted mutagenesis to produce grains rich in resistant starch (RS) but low in glutelin, showing potential benefits for patients with diabetes and kidney diseases. Heat-moisture treatment (HMT) was identified as a simple and effective method to reinforce the nutritional benefits of sbeIIb/Lgc1 rice, leading to significant reductions in in vitro digestibility and enhancements in RS content. HMT also had impacts on a range of physicochemical properties of sbeIIb/Lgc1 rice flour, providing vital data for the food industry to utilize this dual-functional rice flour as a health food ingredient.
Article
Food Science & Technology
Yen-Chun Koh, Hung-Ju Liao
Summary: Starch nanoparticles were prepared by different treatments and their physicochemical properties were characterized. The results showed that the dual-modified starch nanoparticles had higher crystallinity and increased oil absorption capacity, water holding capacity, and solubility compared to the native starch. The modified starches also exhibited changes in crystal type and increased enzymatic resistance.
Article
Food Science & Technology
Yiming Lv, Sen Ma, Jingyao Yan, Binghua Sun, Xiaoxi Wang
Summary: This study investigated the effects of heat-moisture treatment on native highland barley flour. The results showed that the treatment improved the viscosity, gel strength, and crystallinity of the flour, while increasing the content of resistant starch.
Article
Food Science & Technology
Yangyang Sun, Renbing Qin, Jie Zeng, Guanglei Li
Summary: The objective of this study was to investigate the effect of temperature changes during heat-moisture treatment (HMT) on the appearance, structure, and digestibility of sweet potato starch (SPS). The results showed that HMT caused depressions, cavities, and fragments on the surface of SPS particles. The polarized crosses of SPS became irregular and partially blurred, and there were changes in crystallinity, short-range order, and thermal stability of SPS molecules. The resistant starch content of SPS reached its highest level (24.77%) after 4 hours of treatment at 110 degrees C and 25% moisture. These findings can serve as a reference for the modification of SPS.
Article
Biochemistry & Molecular Biology
Yuxiu Zhong, Xiuxiu Yin, Ying Yuan, Xiangli Kong, Shiguo Chen, Xingqian Ye, Jinhu Tian
Summary: This study investigated the effect of heat-moisture treatment (HMT) on the physiochemical properties and in vitro digestibility of corn starch. Different HMT conditions were applied and characterized for their impacts on various properties of corn starch. The results showed that HMT affected the pasting behavior, viscoelasticity, thermal properties, structure, morphology, and digestion of corn starch. The study also found that HMT could lead to the conversion of different starch fractions, potentially resulting in functional starches with improved health properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Laura Martins Fonseca, Natalia Pontes Bona, Rosane Lopes Crizel, Nathalia Stark Pedra, Francieli Moro Stefanello, Loong-Tak Lim, Neftali Lenin Villarreal Carreno, Alvaro Renato Guerra Dias, Elessandra da Rosa Zavareze
Summary: This study aims to produce starch nanofibers as delivery carriers for carvacrol to protect it and ensure optimal release, showing promise in resisting in-vitro digestion and reducing tumoral cells in C6 rat glioma cells without toxicity to astrocytes.
Article
Chemistry, Applied
Igor da Silva Lindemann, Gustavo Heinrich Lang, Cristian de Souza Batista, Shanise Lisie Mello El Halal, Jaqueline Pozzada dos Santos, Nathan Levien Vanier
Summary: This study compared the functional properties of soy protein isolates (SPIs) from stored and non-stored soybeans of different genotypes. Results showed that storage affected the extraction yield, protein hydrophobicity, absorption capacities, and emulsion stability of SPIs. Industries and researchers can use these findings to develop soybean and SPI products with specific characteristics.
Article
Environmental Sciences
Alexandre Lorini, Fernanda M. Damin, Diogo N. de Oliveira, Tassiana Ramires, Cesar V. Rombaldi, Elessandra da R. Zavareze, Alvaro R. G. Dias, Helena T. Godoy, Wladimir P. da Silva, Vanessa Galli, Adriana D. Meinhart
Summary: The study aimed to obtain an edible extract with high content of bioactive compounds and antimicrobial properties from the agricultural residue of Ilex paraguariensis. The optimized extraction conditions allowed for the extraction of 55 compounds, including 8 not previously reported, with high antioxidant activity and the capacity to inhibit Staphylococcus aureus. This method shows promise for valorizing unexplored natural resources.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES
(2022)
Article
Environmental Sciences
W. M. F. Silva, N. P. Bona, N. S. Pedra, K. F. Da Cunha, A. M. Fiorentini, F. M. Stefanello, E. R. Zavareze, A. R. G. Dias
Summary: The study showed that the essential oil of Mentha piperita L. has antioxidant, antibacterial, antitumor, and non-cytotoxic properties. It displayed significant antimicrobial activity against Staphylococcus aureus and Listeria monocytogenes, while also exhibiting cytotoxicity to human epidermal keratinocyte cells. Additionally, the oil showed potent antioxidant activity and antitumor effects on C6 rat glioma cells.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2022)
Article
Food Science & Technology
Felipe Nardo dos Santos, Estefania Julia Dierings de Souza, Tatiane Jessica Siebeneichler, Juliani Buchveitz Pires, Dianini Huttner Kringel, Adriana Dillenburg Meinhart, Alvaro Renato Guerra Dias, Elessandra da Rosa Zavareze
Summary: Jambolan fruit extract, rich in anthocyanins, showed strong antioxidant activity and a wide color variation at different pH values. The optimized extraction conditions resulted in a extract containing a high concentration of anthocyanins, with Del3,5D being the major compound. These findings suggest that jambolan fruit extract has potential as a natural substitute for synthetic dyes and for developing pH-sensitive smart packaging.
FOOD ANALYTICAL METHODS
(2022)
Review
Materials Science, Multidisciplinary
Mohammed Gagaoua, Vania Zanella Pinto, Gulden Goksen, Laura Alessandroni, Melisa Lamri, Amira Leila Dib, Fatma Boukid
Summary: This review discusses the application of electrospinning for quality and safety preservation of meat and processed meat products, including antioxidant and antimicrobial effects, shelf-life extension, and active and intelligent packaging properties. Electrospun fibres have flexibility and advantages, but still face challenges in real-time responsiveness, and are currently limited to research with limited commercial use.
Review
Food Science & Technology
Lara Franco dos Santos, Samuel Teixeira Lopes, Mateus Torres Nazari, Barbara Biduski, Vania Zanella Pinto, Jucilene Sena dos Santos, Telma Elita Bertolin, Luciana Ruschel dos Santos
Summary: The demand for replacing synthetic additives with natural compounds has generated interest in various sectors, particularly the scientific community. By-products such as fruit pomace have been explored as alternative sources for antimicrobial compounds, showing potential applications in food and packaging. This review summarizes the utilization of pomace from different fruits as a source of antibacterial compounds, as well as the extraction methods and applications of these compounds.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Vanderleia Volff, Jessica Kimie de Almeida Rosa Kurosaki, Milena Cia Retcheski, Luiz Vitor Maximovski, Keveen Jhonathan Soares Escorsin, Luciano Tormen, Silvia Romao, Vania Zanella Pinto, Thiago Bergler Bitencourt, Luisa Helena Cazarolli
Summary: This study found that adding Yarrowia lipolytica to the feed of Macrobrachium rosenbergii can improve the body composition of the shrimp and does not affect the quality parameters of the meat during storage. Adding 3% and 5% Yarrowia lipolytica can increase the content of mono- and polyunsaturated fatty acids.
JOURNAL OF AQUATIC FOOD PRODUCT TECHNOLOGY
(2022)
Article
Food Science & Technology
Eliane Lemke Figueiredo, Igor da Silva Lindemann, Shanise Lisie Mello El Halal, Barbara Biduski, Rosana Colussi, Moacir Cardoso Elias, Nathan Levien Vanier
Summary: The study found that glycine and sodium glutamate can effectively prevent browning in the parboiling process of rice, while also resulting in a lighter color. The degree of gelatinization is lower in parboiled rice treated with amino acids, and the percentage of broken grains only increases for certain genotypes.
JOURNAL OF CEREAL SCIENCE
(2022)
Article
Materials Science, Paper & Wood
Aline P. Dresch, Matheus Cavali, David F. Dos Santos, Odinei Fogolari, Vania Z. Pinto, Guilherme M. Mibielli, Joao P. Bender
Summary: The objective of this study was to recover cellulose from pearl millet biomass through chemical pretreatments. The cellulosic fraction was characterized by FTIR, XRD, and Raman spectroscopy. The results showed that the pretreatments effectively removed lignin and hemicelluloses from the pearl millet biomass, indicating their efficiency in improving the fractionation processes of lignocellulosic biomasses.
CELLULOSE CHEMISTRY AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Barbara Biduski, Jarine Amaral do Evangelho, Karina Oliveira Lima, Shanise Lisie de Mello El Halal, Elessandra da Rosa Zavareze, Alvaro Renato Guerra Dias, Vania Zanella Pinto
Summary: Using non-conventional starch with heat-moisture treatment (HMT) can improve film properties and present different properties. HMT causes changes in the structure of pinhao starch, reduces crystallinity, improves thermal stability, and leads to desirable changes in water vapor permeability, tensile strength, and elongation at the break of the starch films. This physical modification method is a promising alternative to chemical modifications.
Review
Food Science & Technology
Iraildo Francisco Soares, Michele Alves de Lima, Robson Alves da Silva, Rosana Colussi
Summary: This review study systematically reviewed the effects of the process in the preparation of kombucha. The results showed that variables such as type of herb, substrate, fermentation time, and temperature in the kombucha production process have an influence on the final product. Further studies are needed to optimize kombucha production by standardizing the amounts of herbs, substrates, fermentation time, and temperature.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Plant Sciences
David Fernando dos Santos, Vandressa Alves, Edlaine Costa, Andre Martins, Alexia Flavia Franca Vieira, Gustavo Henrique Fidelis dos Santos, Catia Tavares dos Passos Francisco, Vania Zanella Pinto
Summary: Ilex paraguariensis, a native tree from South America, is known for its bioactive compounds and its leaves are consumed as hot and cold infusions after a series of processing steps including harvest, flame blanching, drying, and milling. The study investigated the impact of processing on leaf composition by extracting major compounds using different solvent ratios. The solvent ratio EW 50:50 was found to be more effective in extracting chlorogenic acids. The successful extraction of chlorogenic acids from I. paraguariensis proved its promising potential beyond traditional use.
PLANT FOODS FOR HUMAN NUTRITION
(2023)
Article
Food Science & Technology
Leda Battestin Quast, Mariani Zanette, Vania Zanella Pinto, Catia Passos Francisco, Ernesto Quast, Marcos Alceu Felicetti, Marise Bonifacio Queiroz
Summary: This study aimed to obtain co-crystallized honey with sucrose and evaluate its storage characteristics, microbiological stability, and sensory acceptance. The results showed that the physico-chemical properties of co-crystallized honey were not affected by the packaging material used. Microbiological analysis met the regulatory standards. Pineapple juice sweetened with co-crystallized honey showed good sensory acceptance and purchase intention.
JOURNAL OF CULINARY SCIENCE & TECHNOLOGY
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
