Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers

Evolution of oncolytic adenovirus for cancer treatment

(2011) Joung-Woo Choi et al.   ADVANCED DRUG DELIVERY REVIEWS

Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF

(2011) K-J Choi et al.   GENE THERAPY

Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα

(2011) I-K Choi et al.   GENE THERAPY

A Novel Combination Treatment of Armed Oncolytic Adenovirus Expressing IL-12 and GM-CSF with Radiotherapy in Murine Hepatocarcinoma

(2011) Wonwoo KIM et al.   JOURNAL OF RADIATION RESEARCH

Optimizing DC Vaccination by Combination With Oncolytic Adenovirus Coexpressing IL-12 and GM-CSF

(2011) Song-Nan Zhang et al.   MOLECULAR THERAPY

A phase I study of KH901, a conditionally replicating granulocyte-macrophage colony-stimulating factor: Armed oncolytic adenovirus for the treatment of head and neck cancers

(2010) Jianhua Chang et al.   CANCER BIOLOGY & THERAPY

Local Radiation Therapy Inhibits Tumor Growth through the Generation of Tumor-Specific CTL: Its Potentiation by Combination with Th1 Cell Therapy

(2010) Tsuguhide Takeshima et al.   CANCER RESEARCH

Oncolytic (replication-competent) adenoviruses as anticancer agents

(2010) Karoly Toth et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

(2010) A Danielsson et al.   GENE THERAPY

Oncolytic Adenoviruses for the Treatment of Human Cancer: Focus on Translational and Clinical Data

(2010) Sari Pesonen et al.   MOLECULAR PHARMACEUTICS

Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

(2009) Y. Lee et al.   BLOOD

Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis

(2009) J-N Zheng et al.   CANCER GENE THERAPY

Armed replicating adenoviruses for cancer virotherapy

(2009) J J Cody et al.   CANCER GENE THERAPY

Antitumoral Immune Response by Recruitment and Expansion of Dendritic Cells in Tumors Infected with Telomerase-Dependent Oncolytic Viruses

(2009) Edukulla Ramakrishna et al.   CANCER RESEARCH

Cytokine gene-mediated immunotherapy: Current status and future perspectives

(2009) Masahisa Jinushi et al.   CANCER SCIENCE

Targeting the Intratumoral Dendritic Cells by the Oncolytic Adenoviral Vaccine Expressing RANTES Elicits Potent Antitumor Immunity

(2009) Natalia Lapteva et al.   JOURNAL OF IMMUNOTHERAPY

Treatment of Pancreatic Cancer With an Oncolytic Adenovirus Expressing Interleukin-12 in Syrian Hamsters

(2009) Sergia Bortolanza et al.   MOLECULAR THERAPY

Therapeutic and Tumor-specific Immunity Induced by Combination of Dendritic Cells and Oncolytic Adenovirus Expressing IL-12 and 4-1BBL

(2009) Jing-Hua Huang et al.   MOLECULAR THERAPY

Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study

(2008) M. Di Nicola et al.   BLOOD

T-Cell Responses to Survivin in Cancer Patients Undergoing Radiation Therapy

(2008) D. Schaue et al.   CLINICAL CANCER RESEARCH

A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients

(2008) J-L Li et al.   GENE THERAPY