An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

(2009) R. C. Carlisle et al.   BLOOD

CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies

(2009) S S Seregin et al.   GENE THERAPY

Adenovirus Activates Complement by Distinctly Different Mechanisms In Vitro and In Vivo: Indirect Complement Activation by Virions In Vivo

(2009) J. Tian et al.   JOURNAL OF VIROLOGY

Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

(2008) A Danielsson et al.   CANCER GENE THERAPY

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors

(2008) D M Appledorn et al.   GENE THERAPY

The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer

(2008) E Wisse et al.   GENE THERAPY

Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement

(2008) Z. Xu et al.   JOURNAL OF VIROLOGY

Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression

(2008) Sean E Hofherr et al.   MOLECULAR THERAPY

Current Status of Gene Therapy in Asia

(2007) Sunyoung Kim et al.   MOLECULAR THERAPY

Fully Detargeted Polyethylene Glycol-coated Adenovirus Vectors Are Potent Genetic Vaccines and Escape from Pre-existing Anti-adenovirus Antibodies

(2007) Andreas Wortmann et al.   MOLECULAR THERAPY

Modification of Adenovirus Gene Transfer Vectors With Synthetic Polymers: A Scientific Review and Technical Guide

(2007) Florian Kreppel et al.   MOLECULAR THERAPY