Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway

Intake of coffee, caffeine and other methylxanthines and risk of Type I vs Type II endometrial cancer

(2013) S Uccella et al.   BRITISH JOURNAL OF CANCER

Coffee Reduces Risk for Hepatocellular Carcinoma: An Updated Meta-analysis

(2013) Francesca Bravi et al.   Clinical Gastroenterology and Hepatology

Caffeine intake and risk of basal cell and squamous cell carcinomas of the skin in an 11-year prospective study

(2013) Kyoko Miura et al.   EUROPEAN JOURNAL OF NUTRITION

Chemopreventive strategies in hepatocellular carcinoma

(2013) Siddharth Singh et al.   Nature Reviews Gastroenterology & Hepatology

Coffee, Tea, and Fatal Oral/Pharyngeal Cancer in a Large Prospective US Cohort

(2012) J. S. Hildebrand et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Resistance to paclitaxel in hepatoma cells is related to static JNK activation and prohibition into entry of mitosis

(2012) Sunyoung Chae et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Targeting Phosphoinositide 3-Kinase Pathways in Pancreatic Cancer – from Molecular Signalling to Clinical Trials

(2012) Marco Falasca et al.   Anti-Cancer Agents in Medicinal Chemistry

Regulation and cellular functions of class II phosphoinositide 3-kinases

(2012) Marco Falasca et al.   BIOCHEMICAL JOURNAL

Caffeine Increases the Antitumor Effect of Cisplatin in Human Hepatocellular Carcinoma Cells

(2012) Yohei Kawano et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling

(2012) Shun Fujimaki et al.   CANCER LETTERS

Increased Caffeine Intake Is Associated with Reduced Risk of Basal Cell Carcinoma of the Skin

(2012) F. Song et al.   CANCER RESEARCH

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Coffee consumption and reduced risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

(2011) Shane Johnson et al.   CANCER CAUSES & CONTROL

Editorial [Hot Topic: Phosphoinositide 3-Kinase Pathway Inhibitors: Pharmacology, Metabolism & Drug Development (Guest Editor: Marco Falasca)]

(2011) Marco Falasca   CURRENT MEDICINAL CHEMISTRY

PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

(2011) Francesco Dituri et al.   INTERNATIONAL JOURNAL OF CANCER

A Sensitized RNA Interference Screen Identifies a Novel Role for the PI3K p110  Isoform in Medulloblastoma Cell Proliferation and Chemoresistance

(2011) A. S. Guerreiro et al.   MOLECULAR CANCER RESEARCH

Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis

(2011) J A Brazzatti et al.   ONCOGENE

Key Role of Phosphoinositide 3-Kinase Class IB in Pancreatic Cancer

(2010) C. E. Edling et al.   CLINICAL CANCER RESEARCH

PI3K/Akt Signalling Pathway Specific Inhibitors: A Novel Strategy to Sensitize Cancer Cells to Anti-Cancer Drugs

(2010) Marco Falasca   CURRENT PHARMACEUTICAL DESIGN

Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting

(2010) Melanie B. Thomas et al.   JOURNAL OF CLINICAL ONCOLOGY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Systemic Therapy for Hepatocellular Carcinoma: Cytotoxic Chemotherapy, Targeted Therapy and Immunotherapy

(2008) Melanie B. Thomas et al.   ANNALS OF SURGICAL ONCOLOGY

Caffeine Inhibits the Proliferation of Liver Cancer Cells and Activates the MEK/ERK/EGFR Signalling Pathway

(2008) Jun-ichi Okano et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Tenets of PTEN Tumor Suppression

(2008) Leonardo Salmena et al.   CELL

The role of PTEN signaling perturbations in cancer and in targeted therapy

(2008) M Keniry et al.   ONCOGENE

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE