Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases
Authors
Keywords
Prostate cancer, Bone metastasis, Adipocytes, Inflammation, COX-2, CCL2
Journal
CANCER AND METASTASIS REVIEWS
Volume 33, Issue 2-3, Pages 527-543
Publisher
Springer Nature
Online
2014-01-07
DOI
10.1007/s10555-013-9484-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms
- (2015) Mackenzie Herroon et al. Oncotarget
- The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment
- (2015) Kosuke Mizutani et al. NEOPLASIA
- Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
- (2013) Alicia Llorente et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The fat side of prostate cancer
- (2013) Giorgia Zadra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Adipose tissue and adipocytes support tumorigenesis and metastasis
- (2013) Kristin M. Nieman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
- (2013) Shahneen K. Sandhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Interleukin-1 Promotes Skeletal Colonization and Progression of Metastatic Prostate Cancer Cells with Neuroendocrine Features
- (2013) Q. Liu et al. CANCER RESEARCH
- Immunological Goings-on in Visceral Adipose Tissue
- (2013) Diane Mathis Cell Metabolism
- Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells
- (2013) Eiji Kashiwagi et al. ENDOCRINE-RELATED CANCER
- TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE2through Activation of PI3K/AKT/mTOR Pathway
- (2013) BaoHan T. Vo et al. ENDOCRINOLOGY
- Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
- (2013) A. B. Crujeiras et al. FREE RADICAL RESEARCH
- Marrow Fat and Bone—New Perspectives
- (2013) Pouneh K. Fazeli et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- New insights into osteoporosis: the bone-fat connection
- (2013) M. Kawai et al. JOURNAL OF INTERNAL MEDICINE
- Pathophysiology of Human Visceral Obesity: An Update
- (2013) André Tchernof et al. PHYSIOLOGICAL REVIEWS
- Understanding leptin-dependent regulation of skeletal homeostasis
- (2012) Katherine J. Motyl et al. BIOCHIMIE
- Prostate-specific antigen screening for prostate cancer and the risk of overt metastatic disease at presentation
- (2012) Emil Scosyrev et al. CANCER
- Genes associate with abnormal bone cell activity in bone metastasis
- (2012) G. David Roodman CANCER AND METASTASIS REVIEWS
- Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis
- (2012) S. I. Park et al. CANCER RESEARCH
- The Inflammasome Puts Obesity in the Danger Zone
- (2012) Rinke Stienstra et al. Cell Metabolism
- The relationship between adipose tissue and bone metabolism
- (2012) Jeffrey M. Gimble et al. CLINICAL BIOCHEMISTRY
- Marrow Fat and the Bone Microenvironment: Developmental, Functional, and Pathological Implications
- (2012) Clifford J. Rosen et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Adiponectin in Metabolic Bone Disease
- (2012) I. Kanazawa CURRENT MEDICINAL CHEMISTRY
- The inflammation highway: metabolism accelerates inflammatory traffic in obesity
- (2012) Amy R. Johnson et al. IMMUNOLOGICAL REVIEWS
- Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
- (2012) Kenneth J. Pienta et al. INVESTIGATIONAL NEW DRUGS
- Macrophage cathepsin K promotes prostate tumor progression in bone
- (2012) M K Herroon et al. ONCOGENE
- Regulation of COX2 Expression in Mouse Mammary Tumor Cells Controls Bone Metastasis and PGE2-Induction of Regulatory T Cell Migration
- (2012) John Karavitis et al. PLoS One
- Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice
- (2012) M. D. Trottier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Obesity, inflammation and the immune system
- (2012) Fátima Pérez de Heredia et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Lipids and prostate cancer
- (2012) Janel Suburu et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- A high-fat diet enhances proliferation of prostate cancer cells and activates MCP-1/CCR2 signaling
- (2012) Mingguo Huang et al. PROSTATE
- Cancer-Stimulated Mesenchymal Stem Cells Create a Carcinoma Stem Cell Niche via Prostaglandin E 2 Signaling
- (2012) Hua-Jung Li et al. Cancer Discovery
- Obesity is associated with castration-resistant disease and metastasis in men treated with androgen deprivation therapy after radical prostatectomy: results from the SEARCH database
- (2011) Christopher J. Keto et al. BJU INTERNATIONAL
- Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes
- (2011) A. Krings et al. BONE
- Marrow fat metabolism is linked to the systemic energy metabolism
- (2011) Beata Lecka-Czernik BONE
- Prostate cancer in the elderly
- (2011) Emil Scosyrev et al. CANCER
- Targeting apoptosis pathways by Celecoxib in cancer
- (2011) Verena Jendrossek CANCER LETTERS
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells
- (2011) M. Fujita et al. CANCER RESEARCH
- N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells
- (2011) Arun Kumar Nalla et al. EXPERIMENTAL CELL RESEARCH
- Adipokines and the risk of fracture in older adults
- (2011) Kamil E Barbour et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Obesity and fracture in men and women: An epidemiologic perspective
- (2011) Carrie M Nielson et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Absence of MCP-1 leads to elevated bone mass via impaired actin ring formation
- (2011) Ok-Joo Sul et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
- (2011) María Valcárcel et al. Journal of Translational Medicine
- TAK1-TAB2 Signaling Contributes to Bone Destruction by Breast Carcinoma Cells
- (2011) A. Safina et al. MOLECULAR CANCER RESEARCH
- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
- (2011) Bin-Zhi Qian et al. NATURE
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
- (2011) W. W. Pang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Advanced prostate cancer: reinforcing the strings between inflammation and the metastatic behavior
- (2011) G Gueron et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Effects of obesity on bone metabolism
- (2011) Jay J Cao Journal of Orthopaedic Surgery and Research
- From Prostate to Bone: Key Players in Prostate Cancer Bone Metastasis
- (2011) Megan N. Thobe et al. Cancers
- Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice
- (2010) Jay J. Cao et al. Annals of the New York Academy of Sciences
- Fat and bone
- (2010) Ian R. Reid ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Obesity, diabetes mellitus and last but not least, osteoporosis
- (2010) Francisco J. A. de Paula et al. Arquivos Brasileiros de Endocrinologia e Metabologia
- Skeletal aging and the adipocyte program
- (2010) Beata Lecka-Czernik et al. CELL CYCLE
- Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice
- (2010) Ganesh V. Halade et al. EXPERIMENTAL GERONTOLOGY
- Associations between adipokines and obesity-related cancer
- (2010) Gilberto Paz-Filho Frontiers in Bioscience-Landmark
- The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
- (2010) Yoshiki Omatsu et al. IMMUNITY
- Effects of adipocytes on the proliferation and differentiation of prostate cancer cells in a 3-D culture model
- (2010) Arata Kaneko et al. INTERNATIONAL JOURNAL OF UROLOGY
- Saturated fatty acids enhance osteoclast survival
- (2010) S. R. Oh et al. JOURNAL OF LIPID RESEARCH
- High fat diet-induced animal model of age-associated obesity and osteoporosis
- (2010) Ganesh V. Halade et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Obesity Reduces Bone Density Associated with Activation of PPARγ and Suppression of Wnt/β-Catenin in Rapidly Growing Male Rats
- (2010) Jin-Ran Chen et al. PLoS One
- Regression of prostate tumors upon combination of hormone ablation therapy and celecoxib in vivo
- (2010) Parisa Abedinpour et al. PROSTATE
- Leptin Functions Peripherally to Regulate Differentiation of Mesenchymal Progenitor Cells
- (2010) Erica L. Scheller et al. STEM CELLS
- Prostaglandins in bone: bad cop, good cop?
- (2010) Katherine A. Blackwell et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- PPARs in Bone: The Role in Bone Cell Differentiation and Regulation of Energy Metabolism
- (2010) Beata Lecka-Czernik Current Osteoporosis Reports
- Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo
- (2009) Roland Axmann et al. ARTHRITIS AND RHEUMATISM
- High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice
- (2009) Jay J. Cao et al. BONE
- A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone
- (2009) Xin Li et al. CANCER RESEARCH
- Blockade of a Chemokine, CCL2, Reduces Chronic Colitis-Associated Carcinogenesis in Mice
- (2009) B. K. Popivanova et al. CANCER RESEARCH
- Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer
- (2009) Yu-Chi Chen et al. CARCINOGENESIS
- CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
- (2009) Jian Zhang et al. CYTOKINE & GROWTH FACTOR REVIEWS
- In Vitroandin VivoEffects of Adiponectin on Bone
- (2009) Garry A. Williams et al. ENDOCRINOLOGY
- Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats
- (2009) P.-S. Hsieh et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- CCL2 and Interleukin-6 Promote Survival of Human CD11b+Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization
- (2009) Hernan Roca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells
- (2009) Keith R. Shockley et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers
- (2009) Emmanuel S. Antonarakis et al. JOURNAL OF CLINICAL ONCOLOGY
- Osteoclastogenesis by Bone Marrow-Derived Macrophages Is Enhanced in Obese Mice
- (2009) Tae-Wook Kyung et al. JOURNAL OF NUTRITION
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- Obese men have higher-grade and larger tumors: an analysis of the duke prostate center database
- (2009) S J Freedland et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Leptin and adiponectin interact in the regulation of prostate cancer cell growth via modulation of p53 and bcl-2 expression
- (2008) Tina Mistry et al. BJU INTERNATIONAL
- Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): a multi-arm, multistage randomized controlled trial
- (2008) Nicholas D. James et al. BJU INTERNATIONAL
- Continuous PGE2 leads to net bone loss while intermittent PGE2 leads to net bone gain in lumbar vertebral bodies of adult female rats
- (2008) X.Y. Tian et al. BONE
- Osteocytes, mechanosensing and Wnt signaling
- (2008) Lynda F. Bonewald et al. BONE
- Gene expression profile of the bone microenvironment in human fragility fracture bone
- (2008) B. Hopwood et al. BONE
- Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow
- (2008) Anthony Lucci et al. BREAST CANCER RESEARCH AND TREATMENT
- Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen
- (2008) Eric A. Singer et al. CANCER
- Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
- (2008) Yi Lu et al. CLINICAL & EXPERIMENTAL METASTASIS
- Bone and fat connection in aging bone
- (2008) Gustavo Duque CURRENT OPINION IN RHEUMATOLOGY
- Tumor-host interactions: the role of inflammation
- (2008) Marie-Aude Bitoux et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Reduced COX-2 Expression in Aged Mice Is Associated With Impaired Fracture Healing
- (2008) Amish A Naik et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Lipopolysaccharide Induces Macrophage Migration via Prostaglandin D2 and Prostaglandin E2
- (2008) T. Tajima et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The role of non-steroidal anti-inflammatory drugs in the risk of development and treatment of hematologic malignancies
- (2008) Pawel Robak et al. LEUKEMIA & LYMPHOMA
- Soluble EP2 neutralizes prostaglandin E2-induced cell signaling and inhibits osteolytic tumor growth
- (2008) T. Takahashi et al. MOLECULAR CANCER THERAPEUTICS
- Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin-1-Induced Granulocyte Colony-Stimulating Factor Inhibition
- (2008) Zakia Belaid-Choucair et al. STEM CELLS
- Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells
- (2007) Kenichi Miharada et al. JOURNAL OF CELLULAR PHYSIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now