标题
Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases
作者
关键词
Prostate cancer, Bone metastasis, Adipocytes, Inflammation, COX-2, CCL2
出版物
CANCER AND METASTASIS REVIEWS
Volume 33, Issue 2-3, Pages 527-543
出版商
Springer Nature
发表日期
2014-01-07
DOI
10.1007/s10555-013-9484-y
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms
- (2015) Mackenzie Herroon et al. Oncotarget
- The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment
- (2015) Kosuke Mizutani et al. NEOPLASIA
- Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
- (2013) Alicia Llorente et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The fat side of prostate cancer
- (2013) Giorgia Zadra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Adipose tissue and adipocytes support tumorigenesis and metastasis
- (2013) Kristin M. Nieman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
- (2013) Shahneen K. Sandhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Interleukin-1 Promotes Skeletal Colonization and Progression of Metastatic Prostate Cancer Cells with Neuroendocrine Features
- (2013) Q. Liu et al. CANCER RESEARCH
- Immunological Goings-on in Visceral Adipose Tissue
- (2013) Diane Mathis Cell Metabolism
- Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells
- (2013) Eiji Kashiwagi et al. ENDOCRINE-RELATED CANCER
- TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE2through Activation of PI3K/AKT/mTOR Pathway
- (2013) BaoHan T. Vo et al. ENDOCRINOLOGY
- Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
- (2013) A. B. Crujeiras et al. FREE RADICAL RESEARCH
- Marrow Fat and Bone—New Perspectives
- (2013) Pouneh K. Fazeli et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- New insights into osteoporosis: the bone-fat connection
- (2013) M. Kawai et al. JOURNAL OF INTERNAL MEDICINE
- Pathophysiology of Human Visceral Obesity: An Update
- (2013) André Tchernof et al. PHYSIOLOGICAL REVIEWS
- Understanding leptin-dependent regulation of skeletal homeostasis
- (2012) Katherine J. Motyl et al. BIOCHIMIE
- Prostate-specific antigen screening for prostate cancer and the risk of overt metastatic disease at presentation
- (2012) Emil Scosyrev et al. CANCER
- Genes associate with abnormal bone cell activity in bone metastasis
- (2012) G. David Roodman CANCER AND METASTASIS REVIEWS
- Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis
- (2012) S. I. Park et al. CANCER RESEARCH
- The Inflammasome Puts Obesity in the Danger Zone
- (2012) Rinke Stienstra et al. Cell Metabolism
- The relationship between adipose tissue and bone metabolism
- (2012) Jeffrey M. Gimble et al. CLINICAL BIOCHEMISTRY
- Marrow Fat and the Bone Microenvironment: Developmental, Functional, and Pathological Implications
- (2012) Clifford J. Rosen et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Adiponectin in Metabolic Bone Disease
- (2012) I. Kanazawa CURRENT MEDICINAL CHEMISTRY
- The inflammation highway: metabolism accelerates inflammatory traffic in obesity
- (2012) Amy R. Johnson et al. IMMUNOLOGICAL REVIEWS
- Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
- (2012) Kenneth J. Pienta et al. INVESTIGATIONAL NEW DRUGS
- Macrophage cathepsin K promotes prostate tumor progression in bone
- (2012) M K Herroon et al. ONCOGENE
- Regulation of COX2 Expression in Mouse Mammary Tumor Cells Controls Bone Metastasis and PGE2-Induction of Regulatory T Cell Migration
- (2012) John Karavitis et al. PLoS One
- Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice
- (2012) M. D. Trottier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Obesity, inflammation and the immune system
- (2012) Fátima Pérez de Heredia et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Lipids and prostate cancer
- (2012) Janel Suburu et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- A high-fat diet enhances proliferation of prostate cancer cells and activates MCP-1/CCR2 signaling
- (2012) Mingguo Huang et al. PROSTATE
- Cancer-Stimulated Mesenchymal Stem Cells Create a Carcinoma Stem Cell Niche via Prostaglandin E 2 Signaling
- (2012) Hua-Jung Li et al. Cancer Discovery
- Obesity is associated with castration-resistant disease and metastasis in men treated with androgen deprivation therapy after radical prostatectomy: results from the SEARCH database
- (2011) Christopher J. Keto et al. BJU INTERNATIONAL
- Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes
- (2011) A. Krings et al. BONE
- Marrow fat metabolism is linked to the systemic energy metabolism
- (2011) Beata Lecka-Czernik BONE
- Prostate cancer in the elderly
- (2011) Emil Scosyrev et al. CANCER
- Targeting apoptosis pathways by Celecoxib in cancer
- (2011) Verena Jendrossek CANCER LETTERS
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells
- (2011) M. Fujita et al. CANCER RESEARCH
- N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells
- (2011) Arun Kumar Nalla et al. EXPERIMENTAL CELL RESEARCH
- Adipokines and the risk of fracture in older adults
- (2011) Kamil E Barbour et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Obesity and fracture in men and women: An epidemiologic perspective
- (2011) Carrie M Nielson et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Absence of MCP-1 leads to elevated bone mass via impaired actin ring formation
- (2011) Ok-Joo Sul et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
- (2011) María Valcárcel et al. Journal of Translational Medicine
- TAK1-TAB2 Signaling Contributes to Bone Destruction by Breast Carcinoma Cells
- (2011) A. Safina et al. MOLECULAR CANCER RESEARCH
- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
- (2011) Bin-Zhi Qian et al. NATURE
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
- (2011) W. W. Pang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Advanced prostate cancer: reinforcing the strings between inflammation and the metastatic behavior
- (2011) G Gueron et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Effects of obesity on bone metabolism
- (2011) Jay J Cao Journal of Orthopaedic Surgery and Research
- From Prostate to Bone: Key Players in Prostate Cancer Bone Metastasis
- (2011) Megan N. Thobe et al. Cancers
- Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice
- (2010) Jay J. Cao et al. Annals of the New York Academy of Sciences
- Fat and bone
- (2010) Ian R. Reid ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Obesity, diabetes mellitus and last but not least, osteoporosis
- (2010) Francisco J. A. de Paula et al. Arquivos Brasileiros de Endocrinologia e Metabologia
- Skeletal aging and the adipocyte program
- (2010) Beata Lecka-Czernik et al. CELL CYCLE
- Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice
- (2010) Ganesh V. Halade et al. EXPERIMENTAL GERONTOLOGY
- Associations between adipokines and obesity-related cancer
- (2010) Gilberto Paz-Filho Frontiers in Bioscience-Landmark
- The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
- (2010) Yoshiki Omatsu et al. IMMUNITY
- Effects of adipocytes on the proliferation and differentiation of prostate cancer cells in a 3-D culture model
- (2010) Arata Kaneko et al. INTERNATIONAL JOURNAL OF UROLOGY
- Saturated fatty acids enhance osteoclast survival
- (2010) S. R. Oh et al. JOURNAL OF LIPID RESEARCH
- High fat diet-induced animal model of age-associated obesity and osteoporosis
- (2010) Ganesh V. Halade et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Obesity Reduces Bone Density Associated with Activation of PPARγ and Suppression of Wnt/β-Catenin in Rapidly Growing Male Rats
- (2010) Jin-Ran Chen et al. PLoS One
- Regression of prostate tumors upon combination of hormone ablation therapy and celecoxib in vivo
- (2010) Parisa Abedinpour et al. PROSTATE
- Leptin Functions Peripherally to Regulate Differentiation of Mesenchymal Progenitor Cells
- (2010) Erica L. Scheller et al. STEM CELLS
- Prostaglandins in bone: bad cop, good cop?
- (2010) Katherine A. Blackwell et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- PPARs in Bone: The Role in Bone Cell Differentiation and Regulation of Energy Metabolism
- (2010) Beata Lecka-Czernik Current Osteoporosis Reports
- Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo
- (2009) Roland Axmann et al. ARTHRITIS AND RHEUMATISM
- High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice
- (2009) Jay J. Cao et al. BONE
- A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone
- (2009) Xin Li et al. CANCER RESEARCH
- Blockade of a Chemokine, CCL2, Reduces Chronic Colitis-Associated Carcinogenesis in Mice
- (2009) B. K. Popivanova et al. CANCER RESEARCH
- Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer
- (2009) Yu-Chi Chen et al. CARCINOGENESIS
- CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
- (2009) Jian Zhang et al. CYTOKINE & GROWTH FACTOR REVIEWS
- In Vitroandin VivoEffects of Adiponectin on Bone
- (2009) Garry A. Williams et al. ENDOCRINOLOGY
- Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats
- (2009) P.-S. Hsieh et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- CCL2 and Interleukin-6 Promote Survival of Human CD11b+Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization
- (2009) Hernan Roca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells
- (2009) Keith R. Shockley et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers
- (2009) Emmanuel S. Antonarakis et al. JOURNAL OF CLINICAL ONCOLOGY
- Osteoclastogenesis by Bone Marrow-Derived Macrophages Is Enhanced in Obese Mice
- (2009) Tae-Wook Kyung et al. JOURNAL OF NUTRITION
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- Obese men have higher-grade and larger tumors: an analysis of the duke prostate center database
- (2009) S J Freedland et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Leptin and adiponectin interact in the regulation of prostate cancer cell growth via modulation of p53 and bcl-2 expression
- (2008) Tina Mistry et al. BJU INTERNATIONAL
- Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): a multi-arm, multistage randomized controlled trial
- (2008) Nicholas D. James et al. BJU INTERNATIONAL
- Continuous PGE2 leads to net bone loss while intermittent PGE2 leads to net bone gain in lumbar vertebral bodies of adult female rats
- (2008) X.Y. Tian et al. BONE
- Osteocytes, mechanosensing and Wnt signaling
- (2008) Lynda F. Bonewald et al. BONE
- Gene expression profile of the bone microenvironment in human fragility fracture bone
- (2008) B. Hopwood et al. BONE
- Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow
- (2008) Anthony Lucci et al. BREAST CANCER RESEARCH AND TREATMENT
- Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen
- (2008) Eric A. Singer et al. CANCER
- Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
- (2008) Yi Lu et al. CLINICAL & EXPERIMENTAL METASTASIS
- Bone and fat connection in aging bone
- (2008) Gustavo Duque CURRENT OPINION IN RHEUMATOLOGY
- Tumor-host interactions: the role of inflammation
- (2008) Marie-Aude Bitoux et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Reduced COX-2 Expression in Aged Mice Is Associated With Impaired Fracture Healing
- (2008) Amish A Naik et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Lipopolysaccharide Induces Macrophage Migration via Prostaglandin D2 and Prostaglandin E2
- (2008) T. Tajima et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The role of non-steroidal anti-inflammatory drugs in the risk of development and treatment of hematologic malignancies
- (2008) Pawel Robak et al. LEUKEMIA & LYMPHOMA
- Soluble EP2 neutralizes prostaglandin E2-induced cell signaling and inhibits osteolytic tumor growth
- (2008) T. Takahashi et al. MOLECULAR CANCER THERAPEUTICS
- Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin-1-Induced Granulocyte Colony-Stimulating Factor Inhibition
- (2008) Zakia Belaid-Choucair et al. STEM CELLS
- Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells
- (2007) Kenichi Miharada et al. JOURNAL OF CELLULAR PHYSIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started