From Prostate to Bone: Key Players in Prostate Cancer Bone Metastasis

How Do Bisphosphonates Inhibit Bone Metastasis In Vivo

(2015) Pierrick G. Fournier et al.   NEOPLASIA

The crossover of bisphosphonates to cancer therapy

(2010) Merry Sun et al.   Annals of the New York Academy of Sciences

Final safety and efficacy analysis of the specific endothelin A receptor antagonist zibotentan (ZD4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: a double-blind,

(2010) Nicholas D. James et al.   BJU INTERNATIONAL

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach

(2010) Yifei Xing et al.   CANCER BIOLOGY & THERAPY

CXCL12-induced chemotaxis is impaired in T cells from patients with ZAP-70-negative chronic lymphocytic leukemia

(2010) M. Borge et al.   HAEMATOLOGICA

Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

(2010) Katarzyna Grymula et al.   INTERNATIONAL JOURNAL OF CANCER

CXCR7 Protein Is Not Expressed on Human or Mouse Leukocytes

(2010) R. D. Berahovich et al.   JOURNAL OF IMMUNOLOGY

Loss of PTEN Permits CXCR4-Mediated Tumorigenesis through ERK1/2 in Prostate Cancer Cells

(2010) M. A. Chetram et al.   MOLECULAR CANCER RESEARCH

CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

(2010) Ulrike Naumann et al.   PLoS One

Prostate cancer cells modulate osteoblast mineralisation and osteoclast differentiation through Id-1

(2009) H-F Yuen et al.   BRITISH JOURNAL OF CANCER

Independent and cooperative roles of tumor necrosis factor-α, nuclear factor-κB, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of MC3T3-E1 osteoblast-like cell

(2009) Tisheeka R. Graham et al.   CANCER SCIENCE

Denosumab Treatment of Prostate Cancer With Bone Metastases and Increased Urine N-Telopeptide Levels After Therapy With Intravenous Bisphosphonates: Results of a Randomized Phase II Trial

(2009) Karim Fizazi et al.   JOURNAL OF UROLOGY

Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cellsin Vitro

(2009) Daniel E. Frigo et al.   MOLECULAR ENDOCRINOLOGY

 -arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

(2009) S. Rajagopal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth

(2009) Stacy Porvasnik et al.   PROSTATE

Tumor–stroma co-evolution in prostate cancer progression and metastasis

(2009) Sajni Josson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer

(2008) Joel B. Nelson et al.   CANCER

The role of CXC chemokines and their receptors in cancer

(2008) Jo Vandercappellen et al.   CANCER LETTERS

CXCR6 Induces Prostate Cancer Progression by the AKT/Mammalian Target of Rapamycin Signaling Pathway

(2008) J. Wang et al.   CANCER RESEARCH

Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

(2008) Takuya Akashi et al.   CANCER SCIENCE

CXCR6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of PC3 and LNCap cells

(2008) Weidong Hu et al.   CANCER SCIENCE

CXCL16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro

(2008) Y. Lu et al.   MOLECULAR CANCER RESEARCH