Heat shock proteins and high mobility group box 1 protein lack cytokine function

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

(2014) Y. Sha et al.   JOURNAL OF IMMUNOLOGY

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-  Production in Human Monocytes

(2014) J. H. Youn et al.   JOURNAL OF IMMUNOLOGY

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

(2010) S Ben Mkaddem et al.   CELL DEATH AND DIFFERENTIATION

Mycobacterial 65-kD heat shock protein induces release of proinflammatory cytokines from human monocytic cells

(2010) J. S. FRIEDLAND et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

(2010) Emmanuel Lorne et al.   INTENSIVE CARE MEDICINE

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular high mobility group box-1 inhibits R5 and X4 HIV-1 strains replication in mononuclear phagocytes without induction of chemokines and cytokines

(2009) Luca Cassetta et al.   AIDS

Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling

(2009) Clett Erridge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants

(2009) Brian Henderson et al.   CELL STRESS & CHAPERONES

HMGB1 Enhances the Proinflammatory Activity of Lipopolysaccharide by Promoting the Phosphorylation of MAPK p38 through Receptor for Advanced Glycation End Products

(2009) Y.-H. Qin et al.   JOURNAL OF IMMUNOLOGY

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Heat shock proteins and immune system

(2009) Min-Fu Tsan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Factors associated with serum high mobility group box 1 (HMGB1) levels in a general population

(2009) Ako Fukami et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Differential activation of the Toll-like receptor 2/6 complex by lipoproteins of Streptococcus suis serotypes 2 and 9

(2009) Paul J. Wichgers Schreur et al.   VETERINARY MICROBIOLOGY

Chaperone machines in action

(2008) Helen R Saibil   CURRENT OPINION IN STRUCTURAL BIOLOGY

TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

(2008) Ulrich Zähringer et al.   IMMUNOBIOLOGY

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

(2008) Henriette Bendz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The dual immunoregulatory roles of stress proteins

(2008) Alan Graham Pockley et al.   TRENDS IN BIOCHEMICAL SCIENCES