Recent advances on the δ opioid receptor: from trafficking to function

A mu–delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks

(2014) Eric Erbs et al.   Brain Structure & Function

Challenges for opioid receptor nomenclature: IUPHAR Review 9

(2014) Brian M Cox et al.   BRITISH JOURNAL OF PHARMACOLOGY

Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

(2014) Rita Bardoni et al.   NEURON

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The multiple facets of opioid receptor function: implications for addiction

(2013) Pierre-Eric Lutz et al.   CURRENT OPINION IN NEUROBIOLOGY

Effect of δ-Opioid Receptor Activation on BDNF-TrkB vs. TNF-α in the Mouse Cortex Exposed to Prolonged Hypoxia

(2013) Xuesong Tian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spinal   and   Opioids Inhibit Both Thermal and Mechanical Pain in Rats

(2013) A. Normandin et al.   JOURNAL OF NEUROSCIENCE

Bradykinin Controls Pool Size of Sensory Neurons Expressing Functional  -Opioid Receptors

(2013) L. Pettinger et al.   JOURNAL OF NEUROSCIENCE

Learning-Related Translocation of  -Opioid Receptors on Ventral Striatal Cholinergic Interneurons Mediates Choice between Goal-Directed Actions

(2013) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Delta-Opioid Receptors Mediate Unique Plasticity onto Parvalbumin-Expressing Interneurons in Area CA2 of the Hippocampus

(2013) R. A. Piskorowski et al.   JOURNAL OF NEUROSCIENCE

Protein Kinase C  Is Required for Spinal Analgesic Synergy between Delta Opioid and Alpha-2A Adrenergic Receptor Agonist Pairs

(2013) D. J. Schuster et al.   JOURNAL OF NEUROSCIENCE

Differential Control of Opioid Antinociception to Thermal Stimuli in a Knock-In Mouse Expressing Regulator of G-Protein Signaling-Insensitive G o Protein

(2013) J. T. Lamberts et al.   JOURNAL OF NEUROSCIENCE

Role of endogenous opioid peptides in the infarct size-limiting effect of adaptation to chronic continuous hypoxia

(2013) Leonid N. Maslov et al.   LIFE SCIENCES

Chronic Inflammatory Injury Results in Increased Coupling of Delta Opioid Receptors to Voltage-Gated Ca2+ Channels

(2013) Amynah Pradhan et al.   Molecular Pain

15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse

(2013) Pauline Charbogne et al.   NEUROPHARMACOLOGY

Synergistic activity between the delta-opioid agonist SNC80 and amphetamine occurs via a glutamatergic NMDA-receptor dependent mechanism

(2013) Kelly E. Bosse et al.   NEUROPHARMACOLOGY

β-Endorphin via the Delta Opioid Receptor is a Major Factor in the Incubation of Cocaine Craving

(2013) Yahav Dikshtein et al.   NEUROPSYCHOPHARMACOLOGY

Impaired Hippocampus-Dependent and Facilitated Striatum-Dependent Behaviors in Mice Lacking the Delta Opioid Receptor

(2013) Julie Le Merrer et al.   NEUROPSYCHOPHARMACOLOGY

Characterization of a novel model of chronic migraine

(2013) Amynah A. Pradhan et al.   PAIN

Involvement of delta and mu opioid receptors in the acute and sensitized locomotor action of cocaine in mice

(2013) J.H. Kotlinska et al.   PEPTIDES

Endogenous opiates and behavior: 2012

(2013) Richard J. Bodnar   PEPTIDES

δ-Opioid Receptor Activation Modified MicroRNA Expression in the Rat Kidney under Prolonged Hypoxia

(2013) Xiaozhou He et al.   PLoS One

Mu Opioid Receptors on Primary Afferent Nav1.8 Neurons Contribute to Opiate-Induced Analgesia: Insight from Conditional Knockout Mice

(2013) Raphaël Weibel et al.   PLoS One

Delta Opioid Receptors Regulate Temporoammonic-Activated Feedforward Inhibition to the Mouse CA1 Hippocampus

(2013) Xavier Rezai et al.   PLoS One

Identification of a  -  opioid receptor heteromer-biased agonist with antinociceptive activity

(2013) I. Gomes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulator of G protein signaling 4 is a crucial modulator of antidepressant drug action in depression and neuropathic pain models

(2013) M. Stratinaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological traits of delta opioid receptors: pitfalls or opportunities?

(2013) Richard M. van Rijn et al.   PSYCHOPHARMACOLOGY

Select G-Protein-Coupled Receptors Modulate Agonist-Induced Signaling via a ROCK, LIMK, and β-Arrestin 1 Pathway

(2013) Nitish Mittal et al.   Cell Reports

The δ Opioid Receptor Agonist SNC80 Selectively Activates Heteromeric μ–δ Opioid Receptors

(2012) Matthew D. Metcalf et al.   ACS Chemical Neuroscience

Alcohol self-administration, anxiety, and cortisol levels predict changes in delta opioid receptor function in the ventral tegmental area.

(2012) Jennifer M. Mitchell et al.   BEHAVIORAL NEUROSCIENCE

Mouse Delta Opioid Receptors are Located on Presynaptic Afferents to Hippocampal Pyramidal Cells

(2012) Xavier Rezaï et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Selective interactions of spinophilin with the C-terminal domains of the δ- and μ-opioid receptors and G proteins differentially modulate opioid receptor signaling

(2012) Danai-Dionysia Fourla et al.   CELLULAR SIGNALLING

Non-Analgesic Effects of Opioids: Neuroprotection in the Retina

(2012) Shahid Husain et al.   CURRENT PHARMACEUTICAL DESIGN

Case–control association analysis of polymorphisms in the delta-opioid receptor, OPRD1, with cocaine and opioid addicted populations

(2012) R.C. Crist et al.   DRUG AND ALCOHOL DEPENDENCE

Fast Modulation of μ-Opioid Receptor (MOR) Recycling Is Mediated by Receptor Agonists

(2012) Cristina Roman-Vendrell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Opioid Receptor Function in the Dorsal Striatum Plays a Role in High Levels of Ethanol Consumption in Rats

(2012) C. K. Nielsen et al.   JOURNAL OF NEUROSCIENCE

Differential Association of Receptor-G   Complexes with  -Arrestin2 Determines Recycling Bias and Potential for Tolerance of Delta Opioid Receptor Agonists

(2012) N. Audet et al.   JOURNAL OF NEUROSCIENCE

 - and  -Opioid-Related Processes in the Accumbens Core and Shell Differentially Mediate the Influence of Reward-Guided and Stimulus-Guided Decisions on Choice

(2012) V. Laurent et al.   JOURNAL OF NEUROSCIENCE

Distribution of delta opioid receptor-expressing neurons in the mouse hippocampus

(2012) E. Erbs et al.   NEUROSCIENCE

δ-Opioid Receptor Activation and MicroRNA Expression of the Rat Cortex in Hypoxia

(2012) Yilin Yang et al.   PLoS One

Cues predicting drug or food reward restore morphine-induced place conditioning in mice lacking delta opioid receptors

(2012) Julie Le Merrer et al.   PSYCHOPHARMACOLOGY

The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions

(2011) Akiyoshi Saitoh et al.   BEHAVIOURAL BRAIN RESEARCH

Delta opioid receptor analgesia

(2011) Claire Gavériaux-Ruff et al.   BEHAVIOURAL PHARMACOLOGY

Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors

(2011) Urszula Golebiewska et al.   BIOCHEMISTRY

Emergence of Functional Spinal Delta Opioid Receptors After Chronic Ethanol Exposure

(2011) Richard M. van Rijn et al.   BIOLOGICAL PSYCHIATRY

Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies

(2011) Christian Doll et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons

(2011) Vu C Dang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transport of receptors, receptor signaling complexes and ion channels via neuropeptide-secretory vesicles

(2011) Bo Zhao et al.   CELL RESEARCH

The Other Side of Opioid Receptor Signalling: Regulation by Protein-Protein Interaction

(2011) Zafiroula Georgoussi et al.   CURRENT DRUG TARGETS

A Unique Role of RGS9-2 in the Striatum as a Positive or Negative Regulator of Opiate Analgesia

(2011) K. Psigfogeorgou et al.   JOURNAL OF NEUROSCIENCE

Cellular Morphine Tolerance Produced by  Arrestin-2-Dependent Impairment of  -Opioid Receptor Resensitization

(2011) V. C. Dang et al.   JOURNAL OF NEUROSCIENCE

Recovery from  -Opioid Receptor Desensitization after Chronic Treatment with Morphine and Methadone

(2011) N. Quillinan et al.   JOURNAL OF NEUROSCIENCE

Heteromerization of the  - and  -Opioid Receptors Produces Ligand-Biased Antagonism and Alters  -Receptor Trafficking

(2011) L. Milan-Lobo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Preclinical Pharmacology of AZD2327: A Highly Selective Agonist of the  -Opioid Receptor

(2011) T. J. Hudzik et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

(2011) Shao-Qiu He et al.   NEURON

Differential regulation of RGS proteins in the prefrontal cortex of short- and long-term human opiate abusers

(2011) Guadalupe Rivero et al.   NEUROPHARMACOLOGY

Spinal activation of delta opioid receptors alleviates cancer-related bone pain

(2011) V. Otis et al.   NEUROSCIENCE

Hypoxic preconditioning attenuates global cerebral ischemic injury following asphyxial cardiac arrest through regulation of delta opioid receptor system

(2011) C.-J. Gao et al.   NEUROSCIENCE

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia

(2011) Claire Gaveriaux-Ruff et al.   PAIN

The delta opioid receptor: an evolving target for the treatment of brain disorders

(2011) Amynah A. Pradhan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Deletion of the δ Opioid Receptor Gene Impairs Place Conditioning But Preserves Morphine Reinforcement

(2010) Julie Le Merrer et al.   BIOLOGICAL PSYCHIATRY

Agonists at the δ-opioid receptor modify the binding of µ-receptor agonists to the µ-δ receptor hetero-oligomer

(2010) N Kabli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structural organization of the Golgi apparatus

(2010) Martin Lowe   CURRENT OPINION IN CELL BIOLOGY

Disruption of morphine-conditioned place preference by a δ2-opioid receptor antagonist: study of μ-opioid and δ-opioid receptor expression at the synapse

(2010) Sophie K. Billa et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice

(2010) Dave Dubois et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Anti-allodynic effect of the flavonoid myricetin in a rat model of neuropathic pain: Involvement of p38 and protein kinase C mediated modulation of Ca2+ channels

(2010) Tim Hagenacker et al.   EUROPEAN JOURNAL OF PAIN

Human δ opioid receptor biogenesis is regulated via interactions with SERCA2b and calnexin

(2010) Jussi T. Tuusa et al.   FEBS Journal

β-Arrestins Scaffold Cofilin with Chronophin to Direct Localized Actin Filament Severing and Membrane Protrusions Downstream of Protease-activated Receptor-2

(2010) Maria Zoudilova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid Delivery of Internalized Signaling Receptors to the Somatodendritic Surface by Sequence-Specific Local Insertion

(2010) Y. J. Yu et al.   JOURNAL OF NEUROSCIENCE

Multi-component signaling complexes of the δ-opioid receptor with STAT5B and G proteins

(2010) Eirini-Maria Georganta et al.   NEUROPHARMACOLOGY

Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat

(2010) E.K. Joseph et al.   NEUROSCIENCE

Coexpression of  - and  -opioid receptors in nociceptive sensory neurons

(2010) H.-B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global phosphorylation analysis of  -arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)

(2010) K. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors

(2010) Jovita F. Randall-Thompson et al.   PSYCHOPHARMACOLOGY

Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration

(2010) A. Gupta et al.   Science Signaling

The Role of Ubiquitination in Lysosomal Trafficking of δ-Opioid Receptors

(2010) Anastasia G. Henry et al.   TRAFFIC

Molecular modeling studies to predict the possible binding modes of endomorphin analogs in μ opioid receptor

(2009) Xin Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

(2009) Grégory Scherrer et al.   CELL

Regulator of G protein signaling 4 confers selectivity to specific G proteins to modulate μ- and δ-opioid receptor signaling

(2009) Leonidas J. Leontiadis et al.   CELLULAR SIGNALLING

Opioid-receptor-heteromer-specific trafficking and pharmacology

(2009) Richard M van Rijn et al.   CURRENT OPINION IN PHARMACOLOGY

Coexpression of α2A-adrenergic and δ-opioid receptors in substance P-containing terminals in rat dorsal horn

(2009) Maureen S. Riedl et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Autoantibodies to the δ-opioid receptor function as opioid agonists and display immunomodulatory activity

(2009) Parvathi Ranganathan et al.   JOURNAL OF NEUROIMMUNOLOGY

Protein Kinase C Mediates the Synergistic Interaction Between Agonists Acting at  2-Adrenergic and Delta-Opioid Receptors in Spinal Cord

(2009) A. C. Overland et al.   JOURNAL OF NEUROSCIENCE

Disruption of Cdk5-Associated Phosphorylation of Residue Threonine-161 of the  -Opioid Receptor: Impaired Receptor Function and Attenuated Morphine Antinociceptive Tolerance

(2009) W.-Y. Xie et al.   JOURNAL OF NEUROSCIENCE

 -Opioid Receptor Cell Surface Expression Is Regulated by Its Direct Interaction with Ribophorin I

(2009) X. Ge et al.   MOLECULAR PHARMACOLOGY

  Receptors Are Required for Full Inhibitory Coupling of   Receptors to Voltage-Dependent Ca2+ Channels in Dorsal Root Ganglion Neurons

(2009) W. Walwyn et al.   MOLECULAR PHARMACOLOGY

Chronic morphine treatment induces functional delta-opioid receptors in amygdala neurons that project to periaqueductal grey

(2009) Billy Chieng et al.   NEUROPHARMACOLOGY

Role of Mu- and Delta-Opioid Receptors in the Nucleus Accumbens in Cocaine-Seeking Behavior

(2009) Diana Simmons et al.   NEUROPSYCHOPHARMACOLOGY

Differential noxious and motor tolerance of chronic delta opioid receptor agonists in rodents

(2009) H. Beaudry et al.   NEUROSCIENCE

The novel delta opioid receptor agonist UFP-512 dually modulates motor activity in hemiparkinsonian rats via control of the nigro-thalamic pathway

(2009) O.S. Mabrouk et al.   NEUROSCIENCE

Supraspinal role of protein kinase C in oxaliplatin-induced neuropathy in rat

(2009) M. Norcini et al.   PAIN

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

In Vivo Delta Opioid Receptor Internalization Controls Behavioral Effects of Agonists

(2009) Amynah A. A. Pradhan et al.   PLoS One

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sorting of neuropeptides and neuropeptide receptors into secretory pathways

(2009) Xu Zhang et al.   PROGRESS IN NEUROBIOLOGY

Delta-Opioid Receptor Antagonists Prevent Sensitization to the Conditioned Rewarding Effects of Morphine

(2008) Toni S. Shippenberg et al.   BIOLOGICAL PSYCHIATRY

Coexistence and upregulation of three types of opioid receptors, mu, delta and kappa, in human hypertrophic scars

(2008) B. Cheng et al.   BRITISH JOURNAL OF DERMATOLOGY

Ligand stabilization of CXCR4/δ-opioid receptor heterodimers reveals a mechanism for immune response regulation

(2008) Oscar M. Pello et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Peripheral delta opioid receptors require priming for functional competence in vivo

(2008) Matthew P. Rowan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Novel role for the δ-opioid receptor in hypoxic preconditioning in rat retinas

(2008) Pai-Huei Peng et al.   JOURNAL OF NEUROCHEMISTRY

Delta opioid receptors mediate chemotaxis in bone marrow-derived dendritic cells

(2008) Alan Bénard et al.   JOURNAL OF NEUROIMMUNOLOGY

 -Opioid Receptor Expression in the Ventral Tegmental Area Protects Against Elevated Alcohol Consumption

(2008) E. B. Margolis et al.   JOURNAL OF NEUROSCIENCE

In vivo trafficking of endogenous opioid receptors

(2008) Yulin Wang et al.   LIFE SCIENCES

LIM Kinase 1 and Cofilin Regulate Actin Filament Population Required for Dynamin-dependent Apical Carrier Fission from the Trans-Golgi Network

(2008) Susana B. Salvarezza et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct Subcellular Distribution of δ-Opioid Receptor Fused with Various Tags in PC12 Cells

(2008) Hai-Bo Wang et al.   NEUROCHEMICAL RESEARCH

Augmentation of Morphine-Induced Sensitization but Reduction in Morphine Tolerance and Reward in Delta-Opioid Receptor Knockout Mice

(2008) V I Chefer et al.   NEUROPSYCHOPHARMACOLOGY

Cell surface targeting of  -  opioid receptor heterodimers by RTP4

(2008) F. M. Decaillot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE

Opioid and Progesterone Signaling is Obligatory for Early Human Embryogenesis

(2008) Miguel J. Gallego et al.   STEM CELLS AND DEVELOPMENT

An escort for GPCRs: implications for regulation of receptor density at the cell surface

(2008) Lamia Achour et al.   TRENDS IN PHARMACOLOGICAL SCIENCES