Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?

Sympathetic Nervous System-Immune Interactions in Autoimmune Lymphoproliferative Diseases

(2014) Adriana del Rey et al.   NEUROIMMUNOMODULATION

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

The changing scene of amyotrophic lateral sclerosis

(2013) Wim Robberecht et al.   NATURE REVIEWS NEUROSCIENCE

Pathophysiological amyloid concentrations induce sustained upregulation of readthrough acetylcholinesterase mediating anti-apoptotic effects

(2013) G. Li et al.   NEUROSCIENCE

Donepezil for dementia with Lewy bodies: A randomized, placebo-controlled trial

(2012) Etsuro Mori et al.   ANNALS OF NEUROLOGY

Pathobiology of injury after stroke: the neurovascular unit and beyond

(2012) Ulrich Dirnagl   Annals of the New York Academy of Sciences

Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target

(2012) G. Shaltiel et al.   Brain Structure & Function

Butyrylcholinesterase radioligands to image Alzheimer’s disease brain

(2012) Sultan Darvesh   CHEMICO-BIOLOGICAL INTERACTIONS

Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

(2012) Amit Berson et al.   EMBO Molecular Medicine

Acetylcholinesterase inhibitors: a patent review (2008 – present)

(2012) Miroslav Pohanka   EXPERT OPINION ON THERAPEUTIC PATENTS

Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer’s disease

(2012) Paul T Francis et al.   Expert Review of Neurotherapeutics

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(2012) Vladimir Farar et al.   JOURNAL OF NEUROCHEMISTRY

Galantamine administration in chronic post-stroke aphasia

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Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Tangle Formation, Amyloid-β, and Microglia in Alzheimer’s Disease

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The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

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Staurosporine-induced apoptosis presents with unexpected cholinergic effects in a differentiated neuroblastoma cell line

(2012) Guangfeng Li et al.   NEUROCHEMISTRY INTERNATIONAL

Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4

(2012) B. S. Sailaja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-opting Functions of Cholinesterases in Neural, Limb and Stem Cell Development

(2012) Paul G. Layer   PROTEIN AND PEPTIDE LETTERS

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Assembly of Proline-rich Membrane Anchor (PRiMA)-linked Acetylcholinesterase Enzyme

(2011) Vicky P. Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane targeting, shedding and protein interactions of brain acetylcholinesterase

(2011) David Hicks et al.   JOURNAL OF NEUROCHEMISTRY

Enhancing Recovery After Acute Ischemic Stroke with Donepezil as an Adjuvant Therapy to Standard Medical Care: Results of a Phase IIa Clinical Trial

(2011) Kevin M. Barrett et al.   Journal of Stroke & Cerebrovascular Diseases

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   Nature Reviews Neurology

Alternative splicing of mRNA in the molecular pathology of neurodegenerative diseases

(2011) James Dominic Mills et al.   NEUROBIOLOGY OF AGING

Adaptive Alternative Splicing Correlates with Less Environmental Risk of Parkinsonism

(2011) Liat BenMoyal-Segal et al.   Neurodegenerative Diseases

Neural correlates of donepezil-induced cognitive improvement in patients with right hemisphere stroke: A pilot study

(2011) Won Hyuk Chang et al.   NEUROPSYCHOLOGICAL REHABILITATION

A meta-analysis of voxel-based morphometry studies of white matter volume alterations in Alzheimer's disease

(2011) JianPeng Li et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection

(2010) Gregor Zündorf et al.   ANTIOXIDANTS & REDOX SIGNALING

Acetylcholine prevents angiotensin II-induced oxidative stress and apoptosis in H9c2 cells

(2010) Jin-Jun Liu et al.   APOPTOSIS

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway

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PRiMA directs a restricted localization of tetrameric AChE at synapses

(2010) Heidi Q. Xie et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Contributions of selective knockout studies to understanding cholinesterase disposition and function

(2010) Shelley Camp et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of melatonin on neuroinflammation and acetylcholinesterase activity induced by LPS in rat brain

(2010) Ethika Tyagi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The pulse of inflammation: heart rate variability, the cholinergic anti-inflammatory pathway and implications for therapy

(2010) J. M. Huston et al.   JOURNAL OF INTERNAL MEDICINE

Dramatic increase in readthrough acetylcholinesterase in a cellular model of oxidative stress

(2010) Ricarda Härtl et al.   JOURNAL OF NEUROCHEMISTRY

Acetylcholinesterase Variants in Alzheimer’s Disease: From Neuroprotection to Programmed Cell Death

(2010) David S. Greenberg et al.   Neurodegenerative Diseases

Dementia in life writing: our health care system in the words of the sufferer

(2010) Martina Zimmermann   NEUROLOGICAL SCIENCES

Structural and Functional MRI in Mild Cognitive Impairment

(2009) Maija Pihlajamaki et al.   Current Alzheimer Research

Cholinesterases and the basal lamina at vertebrate neuromuscular junctions

(2009) Jean Massoulié et al.   CURRENT OPINION IN PHARMACOLOGY

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

(2009) Morten Thomsen et al.   CURRENT PHARMACEUTICAL DESIGN

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

The Butyrylcholinesterase K Variant Confers Structurally Derived Risks for Alzheimer Pathology♦

(2009) Erez Podoly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Neuroprotective Effects of Nicotine and Acetylcholinesterase Inhibitors: Role of α4 and α7 Receptors in Neuroprotection

(2009) Akinori Akaike et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions

(2009) Ari Meerson et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pro-apoptotic protein–protein interactions of the extended N-AChE terminus

(2009) Debra Toiber et al.   JOURNAL OF NEURAL TRANSMISSION

Targeting of Acetylcholinesterase in Neurons In Vivo: A Dual Processing Function for the Proline-Rich Membrane Anchor Subunit and the Attachment Domain on the Catalytic Subunit

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Changing perspectives regarding late-life dementia

(2009) Majid Fotuhi et al.   Nature Reviews Neurology

Upregulation of α7 Nicotinic Receptors by Acetylcholinesterase C-Terminal Peptides

(2009) Cherie E. Bond et al.   PLoS One

Antisense Treatment for Myasthenia Gravis

(2008) Jon D. Sussman et al.   Annals of the New York Academy of Sciences

Impact of detergents on the activity of acetylcholinesterase and on the effectiveness of its inhibitors

(2008) Martina Zimmermann et al.   BIOLOGICAL CHEMISTRY

A pilot study of rivastigmine in the treatment of delirium after stroke: A safe alternative

(2008) Annemarie W Oldenbeuving et al.   BMC Neurology

An Open-Label Pilot Study of Acetylcholinesterase Inhibitors to Promote Functional Recovery in Elderly Cognitively Impaired Stroke Patients

(2008) Ellen M. Whyte et al.   CEREBROVASCULAR DISEASES

Old and new questions about cholinesterases

(2008) Jean Massoulié et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

(2008) Elliott J Mufson et al.   Expert Review of Neurotherapeutics

Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase

(2008) Dong Liang et al.   FEBS Journal

Non-hydrolytic functions of acetylcholinesterase

(2008) Susan A. Greenfield et al.   FEBS Journal

Amyloid-cholinesterase interactions

(2008) Nibaldo C. Inestrosa et al.   FEBS Journal

The epithelial cholinergic system of the airways

(2008) W. Kummer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility

(2008) I. Mor et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Potent β-Amyloid Modulators

(2008) E. García-Palomero et al.   Neurodegenerative Diseases

N-Acetylcholinesterase-Induced Apoptosis in Alzheimer's Disease

(2008) Debra Toiber et al.   PLoS One

Influence of differential expression of acetylcholinesterase in brain and muscle on respiration

(2008) Eliane Boudinot et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Oxidative stress and erythrocyte acetylcholinesterase (AChE) in hypertensive and ischemic patients of both acute and chronic stages

(2007) Maísa de Carvalho Corrêa et al.   BIOMEDICINE & PHARMACOTHERAPY

Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice

(2007) Gunjan Saxena et al.   EUROPEAN JOURNAL OF PHARMACOLOGY