Twenty-first century mast cell stabilizers

Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions

(2012) Dina S. El-Agamy   EUROPEAN JOURNAL OF PHARMACOLOGY

Evidence questioning cromolyn’s effectiveness and selectivity as a ‘mast cell stabilizer’ in mice

(2012) Tatsuya Oka et al.   LABORATORY INVESTIGATION

Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization

(2012) Meichun Yuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Theanine is a candidate amino acid for pharmacological stabilization of mast cells

(2011) N. H. Kim et al.   AMINO ACIDS

Multiple roles of phosphoinositide-specific phospholipase C isozymes

(2011) Pann-Ghill Suh et al.   BMB Reports

Synthesis of novel mast cell-stabilising and anti-allergic 1,2,3,4-tetrahydro-1-naphthalenols and related compounds

(2011) James W. Barlow et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Novel Imidazo[1,5-b]isoquinolinone Derivative, U63A05, Inhibits Syk Activation in Mast Cells to Suppress IgE-Mediated Anaphylaxis in Mice

(2011) Do Kyun Kim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Novel Mast Cell-Stabilising Amine Derivatives of 3,4-Dihydronaphthalen-1(2H)-one and 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-5-one

(2011) James W. Barlow et al.   Medicinal Chemistry

Phenolic constituents isolated from Fragaria ananassa Duch. inhibit antigen-stimulated degranulation through direct inhibition of spleen tyrosine kinase activation

(2010) Masayuki Ninomiya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and pharmacological evaluation of the individual stereoisomers of 3-[methyl(1,2,3,4-tetrahydro-2-naphthalenyl)amino]-1-indanone, a potent mast cell stabilising agent

(2010) Adam J. Byrne et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A New Class of Human Mast Cell and Peripheral Blood Basophil Stabilizers that Differentially Control Allergic Mediator Release

(2010) Sarah K. Norton et al.   CTS-Clinical and Translational Science

(E,Z)-3-(3′,5′-Dimethoxy-4′-hydroxy-benzylidene)-2-indolinone blocks mast cell degranulation

(2010) S. Kiefer et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Epigallocatechin-3-gallate inhibits mast cell degranulation, leukotriene C4 secretion, and calcium influx via mitochondrial calcium dysfunction

(2010) Toshio Inoue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quercetin and kaempferol suppress immunoglobulin E-mediated allergic inflammation in RBL-2H3 and Caco-2 cells

(2010) Eun-Ju Lee et al.   INFLAMMATION RESEARCH

Morin inhibits Fyn kinase in mast cells and IgE-mediated type I hypersensitivity response in vivo

(2009) Jie Wan Kim et al.   BIOCHEMICAL PHARMACOLOGY

Silibinin Attenuates Mast Cell-Mediated Anaphylaxis-Like Reactions

(2009) Yun Ho Choi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Ellagic Acid Attenuates Immunoglobulin E-Mediated Allergic Response in Mast Cells

(2009) Yun Ho Choi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibitory effects of sesquiterpene lactones isolated from Eupatorium chinense L. on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice

(2009) Tomohiro Itoh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Diastereoisomers of 2-benzyl-2, 3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol: Potential anti-inflammatory agents

(2009) Helen Sheridan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vacuolin-1-modulated exocytosis and cell resealing in mast cells

(2009) Gouse M. Shaik et al.   CELLULAR SIGNALLING

Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cells

(2009) M.-T. Krauth et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A series of 1, 2-coupled indane dimers with mast cell stabilisation and smooth muscle relaxation properties

(2009) H. Sheridan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of dimeric 1,2,3,4-Tetrahydro-naphthalenylamine and Indan-1-ylamine derivatives with mast cell-stabilising and anti-allergic activity

(2009) James W. Barlow et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel anti-ulcer α,β-unsaturated lactones inhibit compound 48/80-induced mast cell degranulation

(2009) Alicia B. Penissi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: Pivotal roles of NF-κB and MAPK

(2009) Ok-Hwa Kang et al.   PHARMACOLOGICAL RESEARCH

Anti-allergic effects of scoparone on mast cell-mediated allergy model

(2009) Y.H. Choi et al.   PHYTOMEDICINE

Suppression of the Antigen-Stimulated RBL-2H3 Mast Cell Activation by Artekeiskeanol A

(2009) JangJa Hong et al.   PLANTA MEDICA

5-Methoxy-8-(2-hydroxy-3-buthoxy-3-methylbutyloxy)-psoralen isolated from Angelica dahurica inhibits cyclooxygenase-2 and 5-Lipoxygenase in mouse bone marrow-derived mast cells

(2008) Jin Mei Hua et al.   ARCHIVES OF PHARMACAL RESEARCH

Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells

(2008) Hyo-Hyun Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Selinidin Suppresses IgE-Mediated Mast Cell Activation by Inhibiting Multiple Steps of FcεRI Signaling

(2008) Sachiko Kishiro et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation

(2008) Tomohiro Itoh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effective Mast Cell Degranulating Peptide Inhibitors of the IgE/FcɛRI Receptor Interaction

(2008) Angeliki Buku et al.   Chemical Biology & Drug Design

Synthesis and evaluation of 4-amino-3,4-dihydro-2H-naphthalen-1-one derivatives as mast cell stabilising and anti-inflammatory compounds

(2008) James W. Barlow et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluvastatin inhibits mast cell degranulation without changing the cytoplasmic Ca2+ level

(2008) Masanori Fujimoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

C3a-derived peptide binds to the type I Fc R and inhibits proximal-coupling signal processes and cytokine secretion by mast cells

(2008) H. Peterfy et al.   INTERNATIONAL IMMUNOLOGY

Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells

(2008) Naoko Miyata et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of the antigen-induced activation of RBL-2H3 cells by sinomenine

(2008) Feng Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

(2008) Elsa Mazuc et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk

(2008) Jun Ho Lee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Na-Tosyl-Phe chloromethyl ketone prevents granule movement and mast cell synergistic degranulation elicited by costimulation of antigen and adenosine

(2008) Satoshi Nunomura et al.   LIFE SCIENCES

Synthesis and pharmacological activity of aminoindanone dimers and related compounds

(2007) H. Sheridan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibitory mechanism of anti-allergic peptides in RBL2H3 cells

(2007) Kyungjong Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis

(2007) Stephen J. Galli et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells

(2007) Hisashi Matsuda et al.   PHYTOMEDICINE

Syk inhibitors as treatment for allergic rhinitis

(2007) Esteban S. Masuda et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS