Role of hypoxia-inducible factors in the dexrazoxane-mediated protection of cardiomyocytes from doxorubicin-induced toxicity

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Hypoxia-inducible factor signaling in the development of tissue fibrosis

(2011) Debra F. Higgins et al.   CELL CYCLE

Iron Regulatory Proteins: From Molecular Mechanisms to Drug Development

(2010) Stefania Recalcati et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of the hypoxia inducible factors HIF in iron metabolism

(2010) Carole Peyssonnaux et al.   CELL CYCLE

Survivin as a global  target of intrinsic tumor suppression networks

(2010) Minakshi Guha et al.   CELL CYCLE

Effects of Iron Deprivation on Multidrug Resistance of Leukemic K562 Cells

(2010) Dingzhu Fang et al.   CHEMOTHERAPY

Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial

(2010) Steven E Lipshultz et al.   LANCET ONCOLOGY

Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection

(2009) Sarah K. Harten et al.   ANTIOXIDANTS & REDOX SIGNALING

Therapeutic Manipulation of the HIF Hydroxylases

(2009) Simon Nagel et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron Homeostasis and Its Interaction with Prolyl Hydroxylases

(2009) David R. Mole   ANTIOXIDANTS & REDOX SIGNALING

Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death

(2009) O Popelová et al.   BRITISH JOURNAL OF CANCER

Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats

(2009) Karol L. Thompson et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death

(2009) Satoru Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The iron chelator Dp44mT does not protect myocytes against doxorubicin

(2009) Brian B. Hasinoff et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes

(2009) Rong Shi et al.   BMC Pharmacology & Toxicology

Iron Depletion by Deferoxamine Up-Regulates Glucose Uptake and Insulin Signaling in Hepatoma Cells and in Rat Liver

(2008) Paola Dongiovanni et al.   AMERICAN JOURNAL OF PATHOLOGY

Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: Role for heme oxygenase-1 down-modulation

(2008) Francesca Bernuzzi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Survivin Determines Cardiac Function by Controlling Total Cardiomyocyte Number

(2008) Bodo Levkau et al.   CIRCULATION

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1 

(2008) C. Riganti et al.   EUROPEAN RESPIRATORY JOURNAL

Differences in doxorubicin-induced apoptotic signaling in adult and immature cardiomyocytes

(2008) Eugene A. Konorev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of HIF-1 and NF-κB Transcription Factors in the Modulation of Transferrin Receptor by Inflammatory and Anti-inflammatory Signals

(2008) Lorenza Tacchini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deferiprone Does Not Protect against Chronic Anthracycline Cardiotoxicity in Vivo

(2008) O. Popelova et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL