Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors

HDAC inhibitors in parasitic diseases

(2011) Katherine T Andrews et al.   IMMUNOLOGY AND CELL BIOLOGY

Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components

(2010) Nicole C. Wheatley et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New insights into the blood-stage transcriptome ofPlasmodium falciparumusing RNA-Seq

(2010) Thomas D. Otto et al.   MOLECULAR MICROBIOLOGY

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery

(2010) C. Garcia-Estrada et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Histone Deacetylases Play a Major Role in the Transcriptional Regulation of the Plasmodium falciparum Life Cycle

(2010) Balbir K. Chaal et al.   PLoS Pathogens

Targeting Histone Deacetylase Inhibitors for Anti-Malarial Therapy

(2009) Katherine Andrews et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase fromPlasmodium falciparum

(2009) Vishal Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

(2009) Guangan Hu et al.   NATURE BIOTECHNOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

(2009) Christopher J Tonkin et al.   PLOS BIOLOGY

Antimalarial Activity of Phenylthiazolyl-Bearing Hydroxamate-Based Histone Deacetylase Inhibitors

(2008) G. S. Dow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues

(2008) K. T. Andrews et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

(2008) Onguma Natalang et al.   BMC GENOMICS

A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum

(2008) Karine G Le Roch et al.   BMC GENOMICS

The Structure and Function of Histone Deacetylases: The Target for Anti-cancer Therapy

(2008) Yingjie Zhang et al.   CURRENT MEDICINAL CHEMISTRY

PlasmoDB: a functional genomic database for malaria parasites

(2008) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates

(2008) Karthikeyan Ganesan et al.   PLoS Pathogens

Isotype expression, post-translational modification and stage-dependent production of tubulins in erythrocytic Plasmodium falciparum

(2007) B.J. Fennell et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY