Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism

Requirement of Nuclear Factor κB for Smac Mimetic–Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis

(2015) Dominic Stadel et al.   NEOPLASIA

Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells

(2012) Bisrat G. Debeb et al.   BREAST CANCER RESEARCH AND TREATMENT

Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy

(2012) P. U. Emeagi et al.   CANCER RESEARCH

Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF- -Independent Apoptosis

(2012) G. Eschenburg et al.   CANCER RESEARCH

Smac mimetic enables the anticancer action of BCG-stimulated neutrophils through TNF-α but not through TRAIL and FasL

(2012) Goodwin Jinesh G. et al.   JOURNAL OF LEUKOCYTE BIOLOGY

XIAP Inhibition and Generation of Reactive Oxygen Species Enhances TRAIL Sensitivity in Inflammatory Breast Cancer Cells

(2012) J. L. Allensworth et al.   MOLECULAR CANCER THERAPEUTICS

Targeting IAP proteins for therapeutic intervention in cancer

(2012) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner

(2012) L Wagner et al.   ONCOGENE

ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells

(2011) Katherine M. Aird et al.   BREAST CANCER RESEARCH AND TREATMENT

In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death and induction of FLIP by NF-κB is required to prevent it

(2011) D M Moujalled et al.   CELL DEATH AND DIFFERENTIATION

Correlation of Smac/DIABLO protein expression with the clinico-pathological features of breast cancer patients

(2011) P. PLUTA et al.   NEOPLASMA

Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer

(2010) Takayuki Iwamoto et al.   BREAST CANCER RESEARCH AND TREATMENT

Inflammatory Breast Cancer: The Disease, the Biology, the Treatment

(2010) Fredika M. Robertson et al.   CA-A CANCER JOURNAL FOR CLINICIANS

X-linked Inhibitor of Apoptosis: A Chemoresistance Factor or a Hollow Promise

(2010) H. Kashkar   CLINICAL CANCER RESEARCH

Prognostic value of the X-linked inhibitor of apoptosis protein for invasive ductal breast cancer with triple-negative phenotype

(2010) Jinjing Wang et al.   HUMAN PATHOLOGY

X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor

(2010) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

XIAP impairs Smac release from the mitochondria during apoptosis

(2010) L Flanagan et al.   Cell Death & Disease

Attenuating Smac mimetic compound 3-induced NF-κB activation by luteolin leads to synergistic cytotoxicity in cancer cells

(2009) Lang Bai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer

(2009) Deborah Silvera et al.   NATURE CELL BIOLOGY

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

(2008) Monzur Rahman et al.   BREAST CANCER RESEARCH AND TREATMENT

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

(2008) J. Lu et al.   CANCER RESEARCH

Acquired Resistance to Small Molecule ErbB2 Tyrosine Kinase Inhibitors

(2008) F. L. Chen et al.   CLINICAL CANCER RESEARCH

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

(2008) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL