ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells

Activation of AMPK is necessary for killing cancer cells and sparing cardiac cells

(2010) Scott A. Shell et al.   CELL CYCLE

Protective role ofortho-substituted Mn(III)N-alkylpyridylporphyrins against the oxidative injury induced bytert-butylhydroperoxide

(2010) Ana S. Fernandes et al.   FREE RADICAL RESEARCH

Resistance to ErbB2 Tyrosine Kinase Inhibitors in Breast Cancer Is Mediated by Calcium-Dependent Activation of RelA

(2010) W. Xia et al.   MOLECULAR CANCER THERAPEUTICS

X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor

(2010) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

Adaptation to Oxidative Stress, Chemoresistance, and Cell Survival

(2009) Matteo Landriscina et al.   ANTIOXIDANTS & REDOX SIGNALING

Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm

(2009) Gazala Khan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Regulation of superoxide dismutase genes: Implications in disease

(2009) Lu Miao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tumor suppressors and cell metabolism: a recipe for cancer growth

(2009) R. G. Jones et al.   GENES & DEVELOPMENT

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Inflammatory Breast Cancer

(2009) Wendy A. Woodward et al.   SEMINARS IN RADIATION ONCOLOGY

Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas

(2008) C. M. Contreras et al.   CANCER RESEARCH

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

(2008) C.-l. Dai et al.   CANCER RESEARCH

Acquired Resistance to Small Molecule ErbB2 Tyrosine Kinase Inhibitors

(2008) F. L. Chen et al.   CLINICAL CANCER RESEARCH

UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

(2008) Alvaro Elorza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blockade of the erbB2 Receptor Induces Cardiomyocyte Death through Mitochondrial and Reactive Oxygen Species-dependent Pathways

(2008) Leo I. Gordon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Study of Predictive Biomarker Profiles for Response Targeting Human Epidermal Growth Factor Receptor 2 (HER-2) in Advanced Inflammatory Breast Cancer With Lapatinib Monotherapy

(2008) Stephen Johnston et al.   JOURNAL OF CLINICAL ONCOLOGY

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

(2008) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

Lapatinib Resistance in HCT116 Cells Is Mediated by Elevated MCL-1 Expression and Decreased BAK Activation and Not by ERBB Receptor Kinase Mutation

(2008) A. P. Martin et al.   MOLECULAR PHARMACOLOGY

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY