Article
Biology
Logan S. James, A. Leonie Baier, Rachel A. Page, Paul Clements, Kimberly L. Hunter, Ryan C. Taylor, Michael J. Ryan
Summary: Stimulation in one sensory modality can affect perception in another modality, resulting in diverse effects including illusions. This study found that cross-modal stimulation can rescue a species-typical acoustic preference in the presence of background noise.
Article
Neurosciences
Luca Ronconi, Andrea Vitale, Alessandra Federici, Noemi Mazzoni, Luca Battaglini, Massimo Molteni, Luca Casartelli
Summary: Audio-visual integration is crucial for social functions and communication in autism spectrum disorder (ASD). Studies have found that oscillatory brain activity in different frequencies play a role in AV integration, with a focus on individual alpha frequency (IAF), pre-/peri-stimulus theta oscillations, and post-stimulus oscillatory phase reset. This study investigates the neural correlates of AV integration in children with ASD and typically developing peers, finding that AV integration dynamics differ between the two groups, suggesting an atypical AV integration process in autism.
Article
Psychology, Multidisciplinary
Chengyao Guo, Nicolas Dupuis-Roy, Jun Jiang, Miaomiao Xu, Xiao Xiao
Summary: This experiment investigated the processing of tactile-visual information conflict in a tactile-visual pairing task, and how it is modulated by tactile-induced emotional states. The results suggest that a positive emotional state induced by tactile stimulation can improve conflict processing abilities in the task.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Biological
Elkan G. Akyurek, Gulsen Balta
Summary: This study investigated visual temporal integration, specifically how multiple stimuli appearing in rapid succession are perceived as a single event. The results showed that both intrinsic and extrinsic factors have an interactive effect on integration performance, with distinct effects on the event-related potential components. This study provides important insights into the neural mechanisms underlying temporal integration and its impact on perception of longer episodic events.
Article
Clinical Neurology
Patrick Dwyer, Xiaodong Wang, Rosanna De Meo-Monteil, Fushing Hsieh, Clifford D. Saron, Susan M. Rivera
Summary: This study examined individual differences in sensory event-related potential (ERP) responses between autistic and typically-developing children, finding substantial heterogeneity in the results. While atypical response morphologies were observed in some autistic participants, there was also considerable overlap between the two groups in terms of brain responses. The utility of using clustering to explore individual differences in brain responses was emphasized as it can expand on and clarify the results of analyses of group mean differences.
Article
Medicine, General & Internal
Krystian Mross, Marta Jankowska, Agnieszka Meller, Karolina Machowska-Sempruch, Przemyslaw Nowacki, Marta Masztalewicz, Wioletta Pawlukowska
Summary: This study investigated sensory integration disorder in patients with multiple sclerosis (MS) and found that these disorders are more severe in MS patients. Additionally, MS patients have more specific sensorimotor abilities.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Teresa A. May-Benson, Alison Teasdale
Summary: The study aimed to examine the inter-rater and test-retest reliability of Sensory Integration Clinical Observations. The findings showed excellent reliability for total score and section scores, indicating that the measure can be administered reliably by multiple raters of varying levels of experience and results are stable over an average two-week interval.
PHYSICAL & OCCUPATIONAL THERAPY IN PEDIATRICS
(2021)
Article
Psychiatry
Ting Lu, Jingjing Yang, Xinyu Zhang, Zihan Guo, Shengnan Li, Weiping Yang, Ying Chen, Nannan Wu
Summary: This study investigated the difference in audiovisual emotional integration between depressed and non-depressed college students. The results showed differences in crossmodal emotional processing mechanisms between the two groups, with the depression group exhibiting larger amplitudes in several brain areas and significantly lower LPP amplitudes in the frontocentral lobe compared to the normal group.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Nanoscience & Nanotechnology
Lin Shao, Xinzhao Xu, Yunqi Liu, Yan Zhao
Summary: The study introduces a multi-modal artificial sensory synapse (MASS) based on an organic synapse to achieve sensory fusion and adaptive memory. The MASS can receive optical, electrical, and pressure information and generate typical synaptic behaviors, resembling multi-sensory neurons in the brain. The research represents a significant step towards next-generation artificial neural networks with adaptive memory capabilities.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Neurosciences
Tomoyo Isoguchi Shiramatsu, Kanato Mori, Kotaro Ishizu, Hirokazu Takahashi
Summary: The study demonstrated that visual MMN exhibited deviance detection properties, with the first-generation focus of visual MMN localized in the visual cortex. Additionally, cross-modal information processing influenced MMN, showing a non-linear relationship between single-modal and cross-modal MMNs.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Neurosciences
Moa G. Peter, Gustav Martensson, Elbrich M. Postma, Love Engstrom Nordin, Eric Westman, Sanne Boesveldt, Johan N. Lundstrom
Summary: Individuals with congenital anosmia showed enhanced multisensory integration performance, suggesting potential reorganization of multisensory processing in the brain. However, no significant group differences were found in olfactory associated regions compared to controls. The results tentatively suggest enhanced processing of audio-visual stimuli in individuals with congenital anosmia may be mediated by multisensory, and not primary sensory, cerebral regions.
Article
Psychology, Biological
Tjerk T. Dercksen, Maria V. Stuckenberg, Erich Schroger, Nicole Wetzel, Andreas Widmann
Summary: This study investigated the influence of stimulus repetition on the elicitation of the prediction error signal and found that higher-level associations applied in a top-down manner are involved in the generation of the prediction error signal, independent from local contingencies.
Article
Pediatrics
Ann Natasja Nielsen, Karen la Cour, Ase Brandt
Summary: The study found that recruitment and introductory materials were effective, but outcome measurements, diaries, and pulse measurements were not working well and needed modifications. Future research may need to focus more on children's subjective experiences and involve teachers more in the study.
Article
Health Care Sciences & Services
Giulia Purpura, Cynthia Y. Y. Lai, Giulia Previtali, Ivan Neil B. Gomez, Trevor W. K. Yung, Luca Tagliabue, Francesco Cerroni, Marco Carotenuto, Renata Nacinovich
Summary: Sensory processing abilities are crucial for child learning, behavioral and emotional regulation, and motor development. Children with neurodevelopmental disabilities often exhibit differences in sensory processing abilities and self-regulation compared to typical children. Therefore, it is important to conduct a comprehensive evaluation of early symptoms and utilize specific tools to better understand and identify these difficulties during childhood.
Article
Mathematics
Pavel Kraikivski
Summary: Perceptual binding, the brain's ability to integrate information from multiple perception pathways to create a unified conscious representation, remains a mechanism that is not well understood. This study presents a computational model that utilizes coupled oscillatory processes to explain the mechanisms behind perceptual binding. The model demonstrates how these processes can modulate each other and reach temporal synchrony, providing insights into the dynamic behavior of perception pathways involved in perceptual binding.
Article
Neurosciences
Xiaomei Lin, Tianyuyi Feng, Erheng Cui, Yunfei Li, Zhang Qin, Xiaohu Zhao
Summary: This study successfully established a rat model based on the genetic-environmental interaction, which exhibited phenotype characteristics similar to human AD in terms of cognitive function, brain microstructure, and immunohistochemistry. The genetic factor (APP mutation) and the environmental factor (acrolein exposure) accounted for 39.74% and 33.3% of the AD-like phenotypes in the model, respectively.
Article
Neurosciences
Gustavo Guimara Guerrero, Giovanna Bignoto Minhoto, Camilla dos Santos Tiburcio-Machado, Itza Amarisis Ribeiro Pinto, Claudio Antonio Federico, Marcia Carneiro Valera
Summary: The present study evaluated the influence of head and neck radiotherapy on the behavior and body weight gain in Wistar rats. The results demonstrated that different doses of radiation induced depressive behavior in the animals, and that the weight gain tended to be lower in the irradiated groups.
Article
Neurosciences
Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei Wu
Summary: This study reveals the underlying mechanisms of the rapid antidepressant effects of merazin hydrate (MH), which activates CaMKII to promote neuronal activities and proliferation in the hippocampus.
Article
Neurosciences
Kathleen E. Murray, Whitney A. Ratliff, Vedad Delic, Bruce A. Citron
Summary: Gulf War Illness (GWI) is a chronic disorder that affects approximately 30% of Veterans deployed to the Persian Gulf. This study found that exposure to toxicants during the Gulf War resulted in long-term changes in the morphology of dentate granule cells and that treatment with Nrf2 activator could improve neuronal health in the hippocampus.
Article
Neurosciences
Jing Li, Yan Zou, Xiangchuang Kong, Yangming Leng, Fan Yang, Guofeng Zhou, Bo Liu, Wenliang Fan
Summary: This study examines the functional connectivity changes in individuals with sudden sensorineural hearing loss (SSNHL) at the integrity, network, and edge levels. The findings reveal reduced intranetwork connectivity strength and increased internetwork connectivity in SSNHL patients. These alterations are associated with the duration of SSNHL and Tinnitus Handicap Inventory scores. The study provides crucial insights into the neural mechanisms of SSNHL and the brain's network-level responses to sensory loss.
Review
Neurosciences
Didier Majou, Anne-Lise Dermenghem
Summary: In the early stages of SAD, memory impairment is strongly correlated with cortical levels of soluble amyloid-beta peptide oligomers. A beta disrupts glutamatergic synaptic function and leads to cognitive deficits. This article describes the pathogenic mechanisms underlying cerebral amyloidosis, involving amyloid precursor protein synthesis, A beta residue clearance processes, and the role of specific molecules.
Article
Neurosciences
Jing Li, Yi Shan, Xiaojing Zhao, Guixiang Shan, Peng-Hu Wei, Lin Liu, Changming Wang, Hang Wu, Weiqun Song, Yi Tang, Guo-Guang Zhao, Jie Lu
Summary: This study investigates changes in brain anatomical structures and functional network connectivity after chronic complete thoracic spinal cord injury (cctSCI) and their impact on clinical outcomes. The findings reveal alterations in gray matter volume and functional connectivity in specific brain regions, indicating potential therapeutic targets and methods for tracking treatment outcomes.
Article
Neurosciences
Anllely Fernandez, Katherine Corvalan, Octavia Santis, Maxs Mendez-Ruette, Ariel Caviedes, Matias Pizarro, Maria -Teresa Gomez, Luis Federico Batiz, Peter Landgraf, Thilo Kahne, Alejandro Rojas-Fernandez, Ursula Wyneken
Summary: This study reveals the importance of SUMOylation in modulating the protein cargo of astrocyte-derived small extracellular vesicles (sEVs) and its potential impact on neurons.
Article
Neurosciences
Anika Luettig, Stefanie Perl, Maria Zetsche, Franziska Richter, Denise Franz, Marco Heerdegen, Ruediger Koehling, Angelika Richter
Summary: This study found that changes in c-Fos activity during short-term stimulation of the entopeduncular nucleus (EPN) are associated with improvement in dystonia, and also discovered that the cerebellum may be involved in the antidystonic effects.
Article
Neurosciences
Yanlin Tao, Wei Shen, Houyuan Zhou, Zikang Li, Ting Pi, Hui Wu, Hailian Shi, Fei Huang, Xiaojun Wu
Summary: Depression has a higher incidence in women compared to men, and this study investigated the impact of sex on depressive behaviors and underlying mechanisms using a corticosterone-induced depression model in mice. The results showed sex-specific anxiety and depression behaviors in the model group, as well as differences in protein expression and neurotransmitter levels between male and female mice. These findings enhance our understanding of sex-specific differences in depression and support tailored interventions.
Review
Neurosciences
Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Chandrakant R. Kokare
Summary: This article discusses the characteristics and importance of the tight junctions of endothelial cells in the CNS, which act as a biological barrier known as the blood-brain barrier (BBB). It focuses on overcoming the challenges of delivering therapeutic agents to the brain in neurodegenerative disorders, particularly multiple sclerosis, through the use of biomaterials. The article also highlights the current limitations of animal models for studying multiple sclerosis and suggests a potential future research direction.
Article
Neurosciences
Li-Min Mao, Khyathi Thallapureddy, John Q. Wang
Summary: Propofol can enhance synapsin phosphorylation and modulate synaptic transmission in the mouse brain. The study reveals the potential role of synapsin as a substrate of propofol and its effects on neurotransmitter release machinery.
Article
Neurosciences
Syed Maaz Ahmed Rizvi, Abdul Baseer Buriro, Irfan Ahmed, Abdul Aziz Memon
Summary: This study explores the effects of prolonged mask usage on the human brain by analyzing EEG and physiological parameters. The results show that the mean EEG spectral power in alpha, beta, and gamma sub-bands of individuals wearing masks is smaller than those without masks. The performances on cognitive tasks and oxygen saturation level differ between the two groups, while blood pressure, body temperature, and heart rate are similar. The analysis also reveals that the occipital and frontal lobes exhibit the greatest variability in channel measurements.
Article
Neurosciences
Rui-Fang Ma, Lu-Lu Xue, Jin-Xiang Liu, Li Chen, Liu-Lin Xiong, Ting-Hua Wang, Fei Liu
Summary: This study observed changes in brain infarction and blood vessels in rats during neonatal hypoxic ischemic encephalopathy (NHIE) modeling using Transcranial Doppler Ultrasonography (TCD). Longer duration of hypoxia was associated with more severe nerve damage. TCD can dynamically monitor cerebral infarction after NHIE modeling, which may serve as a useful auxiliary method for evaluating animal experimental models.
Article
Neurosciences
Yuxiang Dai, Chen Yu, Lu Zhou, Longyang Cheng, Hongbin Ni, Weibang Liang
Summary: Overexpression of CXCR4 in glioma is correlated with patient survival, and its inhibition can reduce invasion and migration of glioma cells. Inhibiting Nur77 also decreases cancer progression associated with CXCR4.